Seminoma differential diagnosis: Difference between revisions
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Testicular seminoma must be differentiated from:<ref name=Unilateraltesticularlesions1>Unilateral testicular lesions. Dr Yuranga Weerakkody and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/unilateral-testicular-lesions. Accessed on February 25, 2016</ref><ref name=Bilateraltesticularlesions1>Bilateral testicular lesions. Dr Matt A. Morgan and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/bilateral-testicular-lesions. Accessed on February 25, 2016</ref> | Testicular seminoma must be differentiated from:<ref name=Unilateraltesticularlesions1>Unilateral testicular lesions. Dr Yuranga Weerakkody and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/unilateral-testicular-lesions. Accessed on February 25, 2016</ref><ref name=Bilateraltesticularlesions1>Bilateral testicular lesions. Dr Matt A. Morgan and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/bilateral-testicular-lesions. Accessed on February 25, 2016</ref> | ||
{{familytree/start |summary=Testicular mass}} | {{familytree/start |summary=Testicular mass}} | ||
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{{familytree |boxstyle=background: #DCDCDC;| | | | | | | B01 | | | | | | | | | | B02 | | | | | | |B01=<div style="width: 12em; padding:0em;">'''Unilateral testicular mass''' </div>|B02=<div style="width: 12em; padding:0em;">'''Bilateral testicular mass'''</div>}} | {{familytree |boxstyle=background: #DCDCDC;| | | | | | | B01 | | | | | | | | | | B02 | | | | | | |B01=<div style="width: 12em; padding:0em;">'''Unilateral testicular mass''' </div>|B02=<div style="width: 12em; padding:0em;">'''Bilateral testicular mass'''</div>}} | ||
{{familytree |boxstyle=background: #DCDCDC;| | | F01 |-|-|^|-|-| F02 | | F03 |-|-|^|-|-| F04 |F01=<div style="width: 12em; padding:0em;">❑'''Neoplastic'''</div>|F02=<div style="width: 12em; padding:0em;">❑'''Non neoplastic'''</div>|F03=<div style="width: 12em; padding:0em;">❑'''Neoplastic'''</div>|F04=<div style="width: 12em; padding:0em;">❑'''Non neoplastic'''</div>}} | {{familytree |boxstyle=background: #DCDCDC;| | | F01 |-|-|^|-|-| F02 | | F03 |-|-|^|-|-| F04 |F01=<div style="width: 12em; padding:0em;">❑'''Neoplastic'''</div>|F02=<div style="width: 12em; padding:0em;">❑'''Non neoplastic'''</div>|F03=<div style="width: 12em; padding:0em;">❑'''Neoplastic'''</div>|F04=<div style="width: 12em; padding:0em;">❑'''Non neoplastic'''</div>}} | ||
{{familytree |boxstyle=background: #DCDCDC;| | | E01 | | | | | | E02 | | E03 | | | | | | E04 | {{familytree |boxstyle=background: #DCDCDC;| | | E01 | | | | | | E02 | | E03 | | | | | | E04 | |E01=<div style="width: 12em; padding:0em;">Non seminomatous germ cell tumor | ||
*Testicular teratoma | *Testicular teratoma | ||
*Testicular epidermoid (teratoma with ectodermal elements only) | *Testicular epidermoid (teratoma with ectodermal elements only) | ||
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*Yolk sac tumor (endodermal sinus tumor) | *Yolk sac tumor (endodermal sinus tumor) | ||
*Mixed germ cell tumor<br> | *Mixed germ cell tumor<br> | ||
Sex cord/stromal | Sex cord/stromal tumors (~2% of testicular malignancies) | ||
*[[Leydig cell tumor]] | *[[Leydig cell tumor]] | ||
*[[Sertoli cell tumor]]> | *[[Sertoli cell tumor]]<br> | ||
[[Metastasis]] to testis|E02=<div style="width: 12em; padding:0em;"> | [[Metastasis]] to testis/div>|E02=<div style="width: 12em; padding:0em;"> | ||
*Testicular cyst | *Testicular cyst | ||
*Tubular ectasia of rete testes (can be bilateral) | *Tubular ectasia of rete testes (can be bilateral) | ||
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*Yolk sac tumor (endodermal sinus tumor) | *Yolk sac tumor (endodermal sinus tumor) | ||
*Mixed germ cell tumor<br> | *Mixed germ cell tumor<br> | ||
Sex cord/stromal | Sex cord/stromal tumors (~2% of testicular malignancies) | ||
*[[Leydig cell tumor]] | *[[Leydig cell tumor]] | ||
*[[Sertoli cell tumor]]<br> | *[[Sertoli cell tumor]]<br> |
Revision as of 16:38, 25 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Differentiating Seminoma from other Diseases
The most common presentation of testicular seminoma is a painless testicular mass.[1] The main differential for testicular mass in young adults is non-seminomatous germ cell tumor (NGCT) which usually appear more heterogenous, often with cysts and calcification.[2] Lymphadenopathy of non-seminomatous germ cell tumor may enhance more heterogenously. Testicular lymphoma is the main differential diagnosis to consider when para-aortic lymphadenopathy is the presenting finding or in the setting of bilateral testicular lesions.[2]
Testicular seminoma must be differentiated from:[3][4]
Differential diagnosis of testicular seminoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Unilateral testicular mass | Bilateral testicular mass | ||||||||||||||||||||||||||||||||||||||||||||||||||||
❑Neoplastic | ❑Non neoplastic | ❑Neoplastic | ❑Non neoplastic | ||||||||||||||||||||||||||||||||||||||||||||||||||
Non seminomatous germ cell tumor
Sex cord/stromal tumors (~2% of testicular malignancies) Metastasis to testis/div> |
| Non seminomatous germ cell tumor
Sex cord/stromal tumors (~2% of testicular malignancies) Metastasis to testis | Non seminomatous germ cell tumor
Sex cord/stromal tumours (~2% of testicular malignancies) Metastasis to testis | ||||||||||||||||||||||||||||||||||||||||||||||||||
References
- ↑ Clinical presentation of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
- ↑ 2.0 2.1 Differential diagnosis of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
- ↑ Unilateral testicular lesions. Dr Yuranga Weerakkody and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/unilateral-testicular-lesions. Accessed on February 25, 2016
- ↑ Bilateral testicular lesions. Dr Matt A. Morgan and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/bilateral-testicular-lesions. Accessed on February 25, 2016