Mast cell tumor classification: Difference between revisions
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==Overview== | ==Overview== | ||
Based on the affected organ(s), mast cell tumor may be classified into | Based on the affected organ(s), mast cell tumor may be classified into two subtypes: cutaneous mastocytosis and systemic mastocytosis. | ||
==Classification== | ==Classification== | ||
Based on the affected organ(s), mast cell tumor may be classified into two subtypes: | Based on the affected organ(s), mast cell tumor may be classified into two subtypes: | ||
Revision as of 00:29, 4 March 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Based on the affected organ(s), mast cell tumor may be classified into two subtypes: cutaneous mastocytosis and systemic mastocytosis.
Classification
Based on the affected organ(s), mast cell tumor may be classified into two subtypes:
- Cutaneous mastocytosis
- Limited to the skin where mast cells infiltrate the skin
- Systemic mastocytosis
- Systemic mastocytosis is caused by mast cells accumulating in the tissues and can affect organs such as the liver, spleen, bone marrow, and small intestine
Mast cell tumor may be classified according to WHO classification into seven subtypes:[1]
- Cutaneous mastocytosis
- Urticaria pigmentosa
- Maculopapular cutaneous mastocytosis
- Diffuse cutaneous mastocytosis
- Mastocytoma of skin
- Indolent systemic mastocytosis
- Smoldering systemic mastocytosis
- Isolated bone marrow mastocytosis
- Systemic mastocytosis with an associated (clonal) hematologic non–mast cell lineage disease
- Aggressive systemic mastocytosis
- Lymphadenopathic systemic mastocytosis with eosinophilia
- Mast cell leukemia
- Typical mast cell leukemia
- Aleukemic mast cell leukemia
- Mast cell sarcoma
- Extracutaneous mastocytoma
References
- ↑ Patnaik MM, Rindos M, Kouides PA, Tefferi A, Pardanani A (2007). "Systemic mastocytosis: a concise clinical and laboratory review". Arch Pathol Lab Med. 131 (5): 784–91. doi:10.1043/1543-2165(2007)131[784:SMACCA]2.0.CO;2. PMID 17488167.