Intravascular large B-cell lymphoma: Difference between revisions

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==Treatment==
==Treatment==
===Medical Therapy===
===Medical Therapy===
 
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
 
|+ '''Treatment of intravascular large B-cell lymphoma<ref name= canadiancancer>Intravascular large B-cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/intravascular-large-b-cell-lymphoma/?region=nb. Accessed on March 9, 2016 </ref>
! style="background: #4479BA; color:#FFF;" | Therapy
! style="background: #4479BA; color:#FFF;" | Description
|-
| style="padding: 5px 5px; background: #DCDCDC;" | [[Chemotherapy]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* Combination therapy :
:* CHOP – [[Cyclophosphamide]] {{and}} [[Doxorubicin]] {{and}} [[Vincristine]] {{and}} [[Prednisone]]
|-
| style="padding: 5px 5px; background: #DCDCDC;" | [[Radiation therapy]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[External beam radiation therapy]] may be used.
|}


==References==
==References==

Revision as of 20:05, 9 March 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Synonyms and keywords:

Overview

Classification

Intravascular large B-cell lymphoma may be classified into either

Intravascular large B-cell lymphoma classification
Name Description

Pathophysiology

Microscopic Pathology

Causes

There are no established causes for intravascular large B-cell lymphoma.

Differentiating type page name here from other Diseases

Intravascular large B-cell lymphoma must be differentiated from other diseases such as:

Epidemiology and Demographics

Age

The incidence of intravascular large B-cell lymphoma increases with age; the median age at diagnosis is 67 years.[1]

Gender

Intravascular large B-cell lymphoma affects men and women equally.[1]

Risk Factors

There are no established risk factors for intravascular large B-cell lymphoma.

Screening

According to the the U.S. Preventive Service Task Force (USPSTF), there is insufficient evidence to recommend routine screening for intravascular large B-cell lymphoma.[2]

Natural History, Complications and Prognosis

  • People with this type of lymphoma can also develop a very serious condition where certain parts of the immune system are activated (hemophagocytic syndrome).[1]
  • Hemophagocytic syndrome causes:


Diagnosis

Symptoms

Symptoms of the intravascular large B-cell lymphoma include:[1]

Physical Examination

Vitals

Skin

  • Skin rash

HEENT

Thorax

Abdomen

Extremities

Laboratory Findings

Laboratory tests for intravascular large B-cell lymphoma include:[1]

Biopsy

Lymph node biopsy is diagnostic of intravascular large B-cell lymphoma.

Other Imaging Findings

CT, MRI, and PET scan may be helpful in the diagnosis of intravascular large B-cell lymphoma.

Treatment

Medical Therapy

Treatment of intravascular large B-cell lymphoma[3]
Therapy Description
Chemotherapy
  • Combination therapy :
Radiation therapy

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Intravascular large B-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf5ae3e27c3994bd54a7/. Accessed on March 09, 2016
  2. ↑ Recommendations. U.S Preventive Services Task Force. Accessed on March 9, 2016
  3. ↑ Intravascular large B-cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/intravascular-large-b-cell-lymphoma/?region=nb. Accessed on March 9, 2016

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