Andersen-Tawil syndrome diagnostic criteria: Difference between revisions
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Revision as of 20:41, 14 March 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Diagnostic Criteria
The diagnosis of Andersen-Tawil syndrome (ATS) is suspected in individuals with either A or B:
A. Two of the following three criteria:
- Periodic paralysis
- Symptomatic cardiac arrhythmias or electrocardiographic (ECG) evidence of enlarged U waves, ventricular ectopy, or a prolonged QTc or QUc interval
- Characteristic facies, dental anomalies, small hands and feet, and at least two of the following:
- Low-set ears
- Widely spaced eyes
- Small mandible
- Fifth-digit clinodactyly
- Syndactyly
B. One of the above three in addition to at least one other family member who meets two of the three criteria.