Pulmonary nodule biopsy: Difference between revisions
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==Overview== | ==Overview== | ||
Biopsy for pulmonary nodule may be classified into 2 categories: non-surgical biopsy and surgical biopsy. Biopsy findings associated with pulmonary nodule will depend on tumor [[histology]]. Common types of lung tissue biopsy for solitary pulmonary nodule, include: conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle aspiration, endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in pulmonary nodule, include: high risk nodule (> 65%), intermediate risk nodule with a high risk patient profile, intermediate risk nodule with a positive positive positron emission tomography scan. | Biopsy for pulmonary nodule may be classified into 2 categories: non-surgical biopsy and surgical biopsy. Biopsy findings associated with pulmonary nodule will depend on tumor [[histology]]. Common types of lung tissue biopsy for solitary pulmonary nodule, include: conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle aspiration, endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in pulmonary nodule, include: high risk nodule (> 65%), intermediate risk nodule with a high risk patient profile, intermediate risk nodule with a positive positive positron emission tomography scan.<ref name="pmid1746503">{{cite journal |vauthors=Herman M, Galanter M, Lifshutz H |title=Combined substance abuse and psychiatric disorders in homeless and domiciled patients |journal=Am J Drug Alcohol Abuse |volume=17 |issue=4 |pages=415–22 |year=1991 |pmid=1746503 |doi= |url=}}</ref><ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref> | ||
==Biopsy== | ==Biopsy== | ||
Biopsy for pulmonary nodule may be classified into 2 categories: | Biopsy for pulmonary nodule may be classified into 2 categories:<ref name="pmid1746503">{{cite journal |vauthors=Herman M, Galanter M, Lifshutz H |title=Combined substance abuse and psychiatric disorders in homeless and domiciled patients |journal=Am J Drug Alcohol Abuse |volume=17 |issue=4 |pages=415–22 |year=1991 |pmid=1746503 |doi= |url=}}</ref> | ||
*'''Non-surgical biopsy''' | *'''Non-surgical biopsy''' | ||
:*Bronchoscopy | :*Bronchoscopy | ||
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:* Wedge resection | :* Wedge resection | ||
*Indications for biopsy in pulmonary nodule, include: | *Indications for biopsy in pulmonary nodule, include:<ref name="pmid1746503">{{cite journal |vauthors=Herman M, Galanter M, Lifshutz H |title=Combined substance abuse and psychiatric disorders in homeless and domiciled patients |journal=Am J Drug Alcohol Abuse |volume=17 |issue=4 |pages=415–22 |year=1991 |pmid=1746503 |doi= |url=}}</ref> | ||
:*High risk nodule (> 65%) | :*High risk nodule (> 65%) | ||
:*Intermediate risk nodule, with a high risk patient profile | :*Intermediate risk nodule, with a high risk patient profile | ||
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:*Characterization of genetic mutations | :*Characterization of genetic mutations | ||
*Contraindications for biopsy in pulmonary nodule, include: | *Contraindications for biopsy in pulmonary nodule, include:<ref name="pmid1746503">{{cite journal |vauthors=Herman M, Galanter M, Lifshutz H |title=Combined substance abuse and psychiatric disorders in homeless and domiciled patients |journal=Am J Drug Alcohol Abuse |volume=17 |issue=4 |pages=415–22 |year=1991 |pmid=1746503 |doi= |url=}}</ref> | ||
:*Emphysema | :*Emphysema | ||
:*Bullous disease | :*Bullous disease | ||
:*Chronic respiratory failure | :*Chronic respiratory failure | ||
*Complications for for biopsy in pulmonary nodule, include: | *Complications for for biopsy in pulmonary nodule, include:<ref name="pmid1746503">{{cite journal |vauthors=Herman M, Galanter M, Lifshutz H |title=Combined substance abuse and psychiatric disorders in homeless and domiciled patients |journal=Am J Drug Alcohol Abuse |volume=17 |issue=4 |pages=415–22 |year=1991 |pmid=1746503 |doi= |url=}}</ref> | ||
:*Pneumothorax | :*Pneumothorax | ||
:*Hemothorax | :*Hemothorax | ||
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'''Bronchoscopy''' | '''Bronchoscopy''' | ||
*Common bronchoscopy biopsy techniques for pulmonary nodule, include: | *Common bronchoscopy biopsy techniques for pulmonary nodule, include:<ref name="pmid1746503">{{cite journal |vauthors=Herman M, Galanter M, Lifshutz H |title=Combined substance abuse and psychiatric disorders in homeless and domiciled patients |journal=Am J Drug Alcohol Abuse |volume=17 |issue=4 |pages=415–22 |year=1991 |pmid=1746503 |doi= |url=}}</ref><ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref> | ||
:*Conventional bronchoscopic-guided transbronchial biopsy | :*Conventional bronchoscopic-guided transbronchial biopsy | ||
:*Bronchoscopic-transbronchial needle aspiration | :*Bronchoscopic-transbronchial needle aspiration | ||
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:*The preferred bronchoscopy biopsy techinque for pulmonary nodule is bronchoscopic-transbronchial needle aspiration. | :*The preferred bronchoscopy biopsy techinque for pulmonary nodule is bronchoscopic-transbronchial needle aspiration. | ||
*Indications for bronchoscopy in pulmonary nodule, include: | *Indications for bronchoscopy in pulmonary nodule, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref> | ||
:*Central nodules | :*Central nodules | ||
:*Large lesions | :*Large lesions | ||
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'''Transthoracic needle biopsy''' | '''Transthoracic needle biopsy''' | ||
*Usually followed by CT guidance | *Usually followed by CT guidance | ||
*Indications for transthoracic needle biopsy in pulmonary nodule, include: | *Indications for transthoracic needle biopsy in pulmonary nodule, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref> | ||
:*Peripheral nodules | :*Peripheral nodules | ||
:*Nodules close to the chest wall | :*Nodules close to the chest wall | ||
Revision as of 15:06, 21 March 2016
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Pulmonary Nodule Microchapters |
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Pulmonary nodule biopsy On the Web |
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American Roentgen Ray Society Images of Pulmonary nodule biopsy |
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Risk calculators and risk factors for Pulmonary nodule biopsy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Biopsy for pulmonary nodule may be classified into 2 categories: non-surgical biopsy and surgical biopsy. Biopsy findings associated with pulmonary nodule will depend on tumor histology. Common types of lung tissue biopsy for solitary pulmonary nodule, include: conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle aspiration, endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in pulmonary nodule, include: high risk nodule (> 65%), intermediate risk nodule with a high risk patient profile, intermediate risk nodule with a positive positive positron emission tomography scan.[1][2]
Biopsy
Biopsy for pulmonary nodule may be classified into 2 categories:[1]
- Non-surgical biopsy
- Bronchoscopy
- Transthoracic needle biopsy
- Needle core biopsy
- Surgical
- Wedge resection
- Indications for biopsy in pulmonary nodule, include:[1]
- High risk nodule (> 65%)
- Intermediate risk nodule, with a high risk patient profile
- Intermediate risk nodule, with a positive positive positron emission scan (PET) scan
- Determination of tumor histologic subtype
- Characterization of genetic mutations
- Contraindications for biopsy in pulmonary nodule, include:[1]
- Emphysema
- Bullous disease
- Chronic respiratory failure
- Complications for for biopsy in pulmonary nodule, include:[1]
- Pneumothorax
- Hemothorax
Non-Surgical Biopsy
Bronchoscopy
- Conventional bronchoscopic-guided transbronchial biopsy
- Bronchoscopic-transbronchial needle aspiration
- Endobronchial ultrasound-guided sheath transbronchial biopsy
- Endobronchial ultrasound-guided transbronchial needle aspiration
- The preferred bronchoscopy biopsy techinque for pulmonary nodule is bronchoscopic-transbronchial needle aspiration.
- Indications for bronchoscopy in pulmonary nodule, include:[2]
- Central nodules
- Large lesions
- No fitness for surgery
- Nodules close to the patent airways
- Patients were the risk of complications from any other biopsy is high
Transthoracic needle biopsy
- Usually followed by CT guidance
- Indications for transthoracic needle biopsy in pulmonary nodule, include:[2]
- Peripheral nodules
- Nodules close to the chest wall
- No fitness for surgery
Surgical Biopsy
- For more information about surgical biopsy of pulmonary nodule, click here
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Herman M, Galanter M, Lifshutz H (1991). "Combined substance abuse and psychiatric disorders in homeless and domiciled patients". Am J Drug Alcohol Abuse. 17 (4): 415–22. PMID 1746503.
- ↑ 2.0 2.1 2.2 2.3 Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM (2004). "Percutaneous biopsy in evaluation of lung nodules". JSLS. 8 (3): 213–6. PMC 3016799. PMID 15347106.