Japanese encephalitis pathophysiology: Difference between revisions
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{{Japanese encephalitis}} | {{Japanese encephalitis}} | ||
{{CMG}} {{AE}} {{AG}} | {{CMG}} {{AE}} {{AG}} | ||
==Overview== | |||
==Pathophysiology== | ==Pathophysiology== | ||
=== | Japanese encephalitis virus is usually transmitted via [[mosquito]]s to the human host. Japanese encephalitis virus contains [[positive-sense ssRNA virus|positive-sense]] viral [[RNA]]; this RNA has its genome directly utilized as if it were mRNA, producing a single protein which is modified by host and viral proteins to form the various proteins needed for [[replication]]. The following table is a summary of the Japanese encephalitis virus:<ref name=ViralZoneFlavi> Flavivirus. SIB Swiss Institute of Bioinformatics. (2015) http://viralzone.expasy.org/viralzone/all_by_species/24.html Accessed on April 12, 2016</ref><ref name=CDCJapEnceph1> Japanese encephalitis - Frequently Asked Questions. CDC Centers for Disease Control and Prevention. (2015) | ||
{| class="wikitable" | |||
! style="text-align: center; font-weight: bold;" | Characteristic | |||
! style="text-align: center; font-weight: bold;" | Data | |||
|- | |||
| Nucleic acid | |||
| [[RNA]] | |||
|- | |||
| Sense | |||
| [[positive-sense ssRNA virus|ssRNA(+)]] | |||
|- | |||
| Virion | |||
| [[enveloped virus|Enveloped]] | |||
|- | |||
| [[Capsid]] | |||
| Spherical | |||
|- | |||
| Symmetry | |||
| Yes; T=3-like organization; [[icosahedral]]-like | |||
|- | |||
| Capsid [[monomers]] | |||
| Unknown | |||
|- | |||
| Envelope length (diameter) | |||
| 50 nm | |||
|- | |||
| Additional envelope information | |||
| Mature virons contain 2 virus-encoded membrane proteins (M and E); immature virons contain a protein precursor | |||
|- | |||
| Genome shape | |||
| Linear | |||
|- | |||
| Genome length | |||
| 10-11 kb | |||
|- | |||
| [[Nucleotide]] cap | |||
| Yes | |||
|- | |||
| [[Polyadenylation|Polyadenylated]] tail | |||
| No; a loop structure is formed instead | |||
|- | |||
| [[Incubation period]] | |||
| 5-15 | |||
|} | |||
Japanese encephalitis (JE) [[virus]] is a [[flavivirus]] which is [[antigen]]ically related to St. Louis encephalitis virus. | Japanese encephalitis (JE) [[virus]] is a [[flavivirus]] which is [[antigen]]ically related to St. Louis encephalitis virus. | ||
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==References== | ==References== | ||
{{ | {{Reflist|2}} | ||
[[Category:Viruses]] | |||
[[Category: | [[Category:Neurology]] | ||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
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Revision as of 14:06, 12 April 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]
Overview
Pathophysiology
Japanese encephalitis virus is usually transmitted via mosquitos to the human host. Japanese encephalitis virus contains positive-sense viral RNA; this RNA has its genome directly utilized as if it were mRNA, producing a single protein which is modified by host and viral proteins to form the various proteins needed for replication. The following table is a summary of the Japanese encephalitis virus:[1]Closing </ref>
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References
- ↑ Flavivirus. SIB Swiss Institute of Bioinformatics. (2015) http://viralzone.expasy.org/viralzone/all_by_species/24.html Accessed on April 12, 2016