Syringoma

Syringoma
Syringomas highlighted by white circles.
ICD-10	D23.9
ICD-9	216
ICD-O:	M8407/0
OMIM	186600
DiseasesDB	31358
MeSH	D018252

WikiDoc Resources for Syringoma
Articles
Most recent articles on Syringoma Most cited articles on Syringoma Review articles on Syringoma Articles on Syringoma in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Syringoma Images of Syringoma Photos of Syringoma Podcasts & MP3s on Syringoma Videos on Syringoma
Evidence Based Medicine
Cochrane Collaboration on Syringoma Bandolier on Syringoma TRIP on Syringoma
Clinical Trials
Ongoing Trials on Syringoma at Clinical Trials.gov Trial results on Syringoma Clinical Trials on Syringoma at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Syringoma NICE Guidance on Syringoma NHS PRODIGY Guidance FDA on Syringoma CDC on Syringoma
Books
Books on Syringoma
News
Syringoma in the news Be alerted to news on Syringoma News trends on Syringoma
Commentary
Blogs on Syringoma
Definitions
Definitions of Syringoma
Patient Resources / Community
Patient resources on Syringoma Discussion groups on Syringoma Patient Handouts on Syringoma Directions to Hospitals Treating Syringoma Risk calculators and risk factors for Syringoma
Healthcare Provider Resources
Symptoms of Syringoma Causes & Risk Factors for Syringoma Diagnostic studies for Syringoma Treatment of Syringoma
Continuing Medical Education (CME)
CME Programs on Syringoma
International
Syringoma en Espanol Syringoma en Francais
Business
Syringoma in the Marketplace Patents on Syringoma
Experimental / Informatics
List of terms related to Syringoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2] Synonyms and keywords: Synonym 1; Synonym 2; Synonym 3

Historical Perspective

• [Disease name] was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
• In [year], [gene] mutations were first identified in the pathogenesis of [disease name].
• In [year], the first [discovery] was developed by [scientist] to treat/diagnose [disease name].

Classification

• [Disease name] may be classified according to [classification method] into [number] subtypes/groups:

• [group1]
• [group2]
• [group3]

• Other variants of [disease name] include [disease subtype 1], [disease subtype 2], and [disease subtype 3].

Pathophysiology

• The pathogenesis of [disease name] is characterized by [feature1], [feature2], and [feature3].
• The [gene name] gene/Mutation in [gene name] has been associated with the development of [disease name], involving the [molecular pathway] pathway.
• On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
• On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

Causes

• [Disease name] may be caused by either [cause1], [cause2], or [cause3].
• [Disease name] is caused by a mutation in the [gene1], [gene2], or [gene3] gene[s].
• There are no established causes for [disease name].

Differentiating Syringoma from other Diseases

• Syringoma must be differentiated from other diseases such as:

• Acne Vulgaris
• Apocrine Hydrocystoma
• Basal Cell Carcinoma
• Colloid Milium
• Cowden Disease(Multiple Hamartoma Syndrome)
• Favre-Racouchot Syndrome(Nodular Elastosis With Cysts and Comedones)
• Granuloma Annulare
• Microcystic Adnexal Carcinoma
• Milia
• Sebaceous Hyperplasia
• Steatocystoma Multiplex
• Trichoepithelioma
• Tuberculosis
• Xanthelasma

Epidemiology and Demographics

• The prevalence of [disease name] is approximately [number or range] per 100,000 individuals worldwide.
• In [year], the incidence of [disease name] was estimated to be [number or range] cases per 100,000 individuals in [location].

Age

• Patients of all age groups may develop [disease name].
• [Disease name] is more commonly observed among patients aged [age range] years old.
• [Disease name] is more commonly observed among [elderly patients/young patients/children].

Gender

• [Disease name] affects men and women equally.
• [Gender 1] are more commonly affected with [disease name] than [gender 2].
• The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.

Race

• There is no racial predilection for [disease name].
• [Disease name] usually affects individuals of the [race 1] race.
• [Race 2] individuals are less likely to develop [disease name].

Risk Factors

• Common risk factors in the development of [disease name] are [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].

Natural History, Complications and Prognosis

• The majority of patients with [disease name] remain asymptomatic for [duration/years].
• Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
• If left untreated, [#%] of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
• Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
• Prognosis is generally [excellent/good/poor], and the [1/5/10¬year mortality/survival rate] of patients with [disease name] is approximately [#%].

Diagnosis

Diagnostic Criteria

• The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met:

• [criterion 1]
• [criterion 2]
• [criterion 3]
• [criterion 4]

History

• A positive family history of syringoma may be present.
• The majority of patients with syringoma are asymptomatic.

Symptoms

• [Disease name] is usually asymptomatic.
• Symptoms of [disease name] may include the following:

• [symptom 1]
• [symptom 2]
• [symptom 3]
• [symptom 4]
• [symptom 5]
• [symptom 6]

Physical Examination

• Patients with [disease name] usually appear [general appearance].
• Physical examination may be remarkable for:

• [finding 1]
• [finding 2]
• [finding 3]
• [finding 4]
• [finding 5]
• [finding 6]

Laboratory Findings

• There are no specific laboratory findings associated with [disease name].

• A [positive/negative] [test name] is diagnostic of [disease name].
• An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of [disease name].
• Other laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

Imaging Findings

• There are no [imaging study] findings associated with [disease name].
• [Imaging study 1] is the imaging modality of choice for [disease name].
• On [imaging study 1], [disease name] is characterized by [finding 1], [finding 2], and [finding 3].
• [Imaging study 2] may demonstrate [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

• [Disease name] may also be diagnosed using [diagnostic study name].
• Findings on [diagnostic study name] include [finding 1], [finding 2], and [finding 3].

Treatment

Medical Therapy

• There is no treatment for [disease name]; the mainstay of therapy is supportive care.
• The mainstay of therapy for [disease name] is [medical therapy 1] and [medical therapy 2].
• [Medical therapy 1] acts by [mechanism of action1].
• Response to [medical therapy 1] can be monitored with [test/physical finding/imaging] every [frequency/duration].

Surgery

• Surgery is the mainstay of therapy for [disease name].
• [Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of [disease name].
• [Surgical procedure] can only be performed for patients with [disease stage] [disease name].

Prevention

• There are no primary preventive measures available for [disease name].
• Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].

• Once diagnosed and successfully treated, patients with [disease name] are followed-up every [duration]. Follow-up testing includes [test 1], [test 2], and [test 3].

Gallery

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  Syringoma From Public Health Image Library (PHIL).

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  Syringoma From Public Health Image Library (PHIL).

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  Syringoma From Public Health Image Library (PHIL).

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  Syringoma From Public Health Image Library (PHIL).

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  Syringoma From Public Health Image Library (PHIL).

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  Syringoma From Public Health Image Library (PHIL).

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  Syringoma From Public Health Image Library (PHIL).