Drug induced liver injury causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Causes

Common Causes

• Acetaminophen
• Azithromycin
• Ethanol
• Statins
• Tetracycline
• Rosiglitazone
• Amiodarone
• Valproic Acid
• Methotrexate
• Isoniazid
• Rifampin

Causes by Organ System

Cardiovascular	No underlying causes
Chemical / poisoning	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	5-Azacytidine, Abacavir, Abiraterone, Acetaminophen, Agomelatine, Albendazole, Allopurinol, Altretamine, Amineptine, Amiodarone, Amitriptyline, Amoxicillin, Amphotericin B, Amprenavir, Anabolic steroids, Antituberculosis drugs, Apixaban, Arsenic trioxide, Asafetida, Asparaginase, Atorvastatin, Atovaquone, Azathioprine, Benoxaprofen, Bexarotene, Black cohosh extract, Bosentan, Bosutinib, Bromfenac, Bumetanide, Carfilzomib, Cascara, Caspofungin, Chaparral, Chenodeoxycholic acid, Chlormezanone, Chlorzoxazone, Ciprofloxacin, Clofarabine, Combined oral contraceptive pill, Comfrey, Crizotinib, Cyclobenzaprine, Dantrolene, Daptomycin, Dasatinib, Deferasirox, Desipramine, Diclofenac, Disulfiram, Docetaxel, Donepezil, Dothiepin, Dronedarone, Eltrombopag, Emtricitabine, Entecavir, Ephedra, Erlotinib, Erythromycin estolate, Ethanol, Ethinylestradiol, Ethionamide, Etretinate, Febuxostat, Felbamate, Fenofibrate, Fingolimod, Fluconazole, Flucytosine, Fluoxymesterone, Flutamide, Fluvastatin, Fosamprenavir, Frusemide, Fusidic acid, Ganciclovir, Gemcitabine, Gemtuzumab ozogamicin, Gold salts, Golimumab, Halothane, Imatinib mesylate, Imipenem, Interferon alpha, Interferon beta, Interleukin 2, Ipilimumab, Isoniazid, Isotretinoin, Kava root extract, Ketoconazole, Lapatinib ditosylate, Leflunomide, Lovastatin, Maraviroc, Meropenem, Mesalazine, Methotrexate, Methyldopa, Methyldopate, Micafungin, Minocycline, Mirtazapine, Mithramycin, Naltrexone, Nandrolone, Natalizumab, Nelfinavir, Nevirapine, Niacin, Nicotinic acid, Nimesulide, Nitisinone, Nitrofurantoin, Norfloxacin, Nortriptyline, Ondansetron, Oxyphenisatine, Paclitaxel, Para-amino salicylic acid, Pazopanib, Pegvisomant, Pemoline, Pentostatin, Phenelzine, Phenylbutazone, Phenytoin, Pralatrexate, Pravastatin, Procainamide, Propylthiouracil, Prothionamide, Pyrazinamide, Pyritinol, Pyrrolizidine alkaloids, Regorafenib, Rifabutin, Rifampicin, Riluzole, Ritonavir, Rivaroxaban, Rosuvastatin, Saquinavir, Simvastatin, Sitaxentan, Sorafenib, Stanozolol, Statins, Succimer, Suloctidil, Sulphasalazine, Sulphinpyrazone, Tegafur, Telithromycin, Teriflunomide, Thiabendazole, Thioguanine, Ticlopidine, Tipranavir, Tizanidine, Tolbutamide, Tolcapone, Tolrestat, Trabectedin, Troglitazone, Trovafloxacin, Ursodeoxycholic acid, Valganciclovir, Valproic acid, Velnacrine, Verapamil, Voriconazole, Ximelagatran, Zotepine, Alcohol, Carbimazole, Phenothiazines, Clofibrate, Tetracyclines
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	No underlying causes
Musculoskeletal / Ortho	No underlying causes
Neurologic	No underlying causes
Nutritional / Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	No underlying causes
Opthalmologic	No underlying causes
Overdose / Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal / Electrolyte	No underlying causes
Rheum / Immune / Allergy	No underlying causes
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Dental	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

5-Azacytidine Abacavir Abiraterone Acetaminophen Agomelatine Albendazole Alcohol Allopurinol Altretamine Amineptine Amiodarone Amitriptyline Amoxicillin Amphotericin B Amprenavir Anabolic steroids Antituberculosis drugs Apixaban Arsenic trioxide Asafetida Asparaginase Atorvastatin Atovaquone Azathioprine Benoxaprofen Bexarotene Black cohosh extract Bosentan Bosutinib Bromfenac Bumetanide Carbimazole Carfilzomib Cascara Caspofungin Chaparral Chenodeoxycholic acid Chlormezanone Chlorzoxazone Ciprofloxacin Clofarabine Clofibrate Combined oral contraceptive pill Comfrey Crizotinib Cyclobenzaprine Dantrolene Daptomycin Dasatinib Deferasirox Desipramine Diclofenac Disulfiram Docetaxel Donepezil Dothiepin Dronedarone Eltrombopag Emtricitabine Entecavir Ephedra Erlotinib Erythromycin estolate Ethanol Ethinylestradiol Ethionamide Etretinate Febuxostat Felbamate Fenofibrate Fingolimod Fluconazole Flucytosine Fluoxymesterone Flutamide Fluvastatin Fosamprenavir Frusemide Fusidic acid Ganciclovir Gemcitabine Gemtuzumab ozogamicin Gold salts Golimumab Halothane Imatinib mesylate Imipenem Interferon alpha Interferon beta Interleukin 2 Ipilimumab Isoniazid

Isotretinoin Kava root extract Ketoconazole Lapatinib ditosylate Leflunomide Lovastatin Maraviroc Meropenem Mesalazine Methotrexate Methyldopa Methyldopate Micafungin Minocycline Mirtazapine Mithramycin Naltrexone Nandrolone Natalizumab Nelfinavir Nevirapine Niacin Nicotinic acid Nimesulide Nitisinone Nitrofurantoin Norfloxacin Nortriptyline Ondansetron Oxyphenisatine Paclitaxel Para-amino salicylic acid Pazopanib Pegvisomant Pemoline Pentostatin Phenelzine Phenothiazines Phenylbutazone Phenytoin Pralatrexate Pravastatin Procainamide Propylthiouracil Prothionamide Pyrazinamide Pyritinol Pyrrolizidine alkaloids Regorafenib Rifabutin Rifampicin Riluzole Ritonavir Rivaroxaban Rosuvastatin Saquinavir Simvastatin Sitaxentan Sorafenib Stanozolol Statins Succimer Suloctidil Sulphasalazine Sulphinpyrazone Tegafur Telithromycin Teriflunomide Tetracyclines Thiabendazole Thioguanine Ticlopidine Tipranavir Tizanidine Tolbutamide Tolcapone Tolrestat Trabectedin Troglitazone Trovafloxacin Ursodeoxycholic acid Valganciclovir Valproic acid Velnacrine Verapamil Voriconazole Ximelagatran Zotepine