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| | {{Autoimmune hemolytic anemia (patient information)}} |
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| '''For the WikiDoc page for this topic, click [[Autoimmune hemolytic anemia|here]]''' | | '''For the WikiDoc page for this topic, click [[Autoimmune hemolytic anemia|here]]''' |
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| {{Infobox_Disease | | | {{CMG}} |
| Name = Autoimmune hemolytic anemia |
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| DiseasesDB = |
| | ==Overview== |
| ICD10 = {{ICD10|D|59|0|d|55}}-{{ICD10|D|59|1|d|55}} |
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| ICD9 = {{ICD9|283.0}} |
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| ICDO = |
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| OMIM = |
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| MedlinePlus = 000579 |
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| MeshID = D000744 |
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| }}
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| {{SI}}
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| '''Editor-in-Chief:''' [[C. Michael Gibson]], M.S.,M.D. [mailto:charlesmichaelgibson@gmail.com] Phone:617-632-7753; '''Associate Editor-In-Chief:''' [[Lakshmi Gopalakrishnan]], M.B.B.S.
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| '''''Synonyms and Keywords:''''' Idiopathic autoimmune hemolytic anemia
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| ==Overview==
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| Autoimmune hemolytic anemia is a drop in the number of red blood cells due to '''increased destruction by the body's defense (immune) system.'''
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| ==What are the symptoms of Autoimmune hemolytic anemia?== | | ==What are the symptoms of Autoimmune hemolytic anemia?== |
| *[[Dark urine]]
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| *[[Fatigue]]
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| *Pale color ([[pallor]])
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| *Rapid heartbeat
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| *[[Shortness of breath]]
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| *Yellow skin color ([[jaundice]])
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| ==What causes Autoimmune hemolytic anemia?== | | ==What causes Autoimmune hemolytic anemia?== |
| *Autoimmune hemolytic anemia is an acquired disease that occurs when antibodies form against a person's own red blood cells. In the idiopathic form of this disease, the cause is unknown.
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| *'''Idiopathic''' autoimmune hemolytic anemia accounts for one-half of all immune hemolytic anemias.
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| *There are '''other types''' of immune hemolytic anemias in which the cause may result from an underlying disease or medication. The disease may start quickly and be very serious.
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| ==Who is at highest risk?==
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| Risk factors are not known.
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| ==When to seek urgent medical care?== | | ==When to seek urgent medical care?== |
| Call your health care provider if you notice symptoms of [[Anemia (patient information)|anemia]].
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| ==Diagnosis== | | ==Diagnosis== |
| *An examination may reveal an '''enlarged spleen'''.
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| *'''Tests''' include:
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| :*Direct [[Coombs test]]
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| :*[[Hemoglobin]] in the urine
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| :*Indirect Coombs' test
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| :*Red blood cell count and serum [[hemoglobin]]
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| :*[[Reticulocyte count]]
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| :*Serum [[bilirubin]] levels
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| :*Serum [[haptoglobin]]
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| ==Treatment options== | | ==Treatment options== |
| *The first therapy tried is usually a steroid medication, such as '''[[prednisone]]'''.
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| *If steroid medications do not improve the condition, removal of the spleen ('''[[splenectomy]]''') may be considered.
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| *Therapy to '''suppress the immune system''' is usually given if the person does not respond to steroids and splenectomy. Medications such as [[azathioprine]] (Imuran), [[cyclophosphamide]] (Cytoxan), and [[rituximab]] (Rituxan) have been used.
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| *'''[[Blood transfusions]]''' are given with caution, because of the potential that blood may not be compatible and may cause further hemolysis.
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| ==Where to find medical care for Autoimmune hemolytic anemia?==
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| [http://maps.google.com/maps?f=q&hl=en&geocode=&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|Autoimmune hemolytic anemia}}}}&sll=37.0625,-95.677068&sspn=65.008093,112.148438&ie=UTF8&ll=37.0625,-95.677068&spn=91.690419,149.414063&z=2&source=embed Directions to Hospitals Treating Autoimmune hemolytic anemia]
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| ==Prevention== | | |
| There is no known prevention for autoimmune hemolytic anemia, because the cause is '''unknown'''.
| | ==Where to find medical care for Autoimmune hemolytic anemia?== |
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| ==What to expect (Outlook/Prognosis)?== | | ==What to expect (Outlook/Prognosis)?== |
| *Adults may have long-term disease that keeps returning.
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| *In children the anemia is usually short-lived.
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| ==Possible complications== | | ==Possible complications== |
| *Infection (as a complication of treatment)
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| *Severe [[Anemia (patient information)|anemia]]
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| ==Source==
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| http://www.nlm.nih.gov/medlineplus/ency/article/000579.htm
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| {{WH}}
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| {{WS}}
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| [[Category:Mature chapter]] | | ==Prevention== |
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| | ==Source== |
| | https://www.nlm.nih.gov/medlineplus/ency/article/000586.htm |
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| | [[Category:primary care]] |
| [[Category:Disease]] | | [[Category:Disease]] |
| [[Category:Hematology]] | | [[Category:Hematology]] |
| [[Category:Hematology patient information]] | | [[Category:Blood disorders]] |
| | [[Category:Blood tests]] |
| | [[Category:Patient information]] |