Altitude sickness laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Chronic mountain sickness (CMS) is characterized by [[polycythemia]] (increased [[hematocrit]]) and [[hypoxemia]] which both decrease on descent from altitude. CMS is believed to arise because of an excessive production of [[red blood cell]]s, which increases the oxygen carrying capacity of the blood but may cause increased blood viscosity and uneven blood flow through the lungs ([[V/Q mismatch]]). However, CMS is also considered an adaptation of pulmonary and [[heart disease]] to life under chronic [[hypoxia]] at altitude.<ref name="pmid17072074">{{cite journal| author=Zubieta-Castillo G, Zubieta-Calleja GR, Zubieta-Calleja L| title=Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia. | journal=J Physiol Pharmacol | year= 2006 | volume= 57 Suppl 4 | issue= | pages= 431-42 | pmid=17072074 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17072074 }} </ref> [[Clinical]] diagnosis by laboratory indicators have ranges of: [[Hemoglobin|Hb]] > 200 g/L, [[Hematocrit|Hct]] > 65%, and [[arterial oxygen saturation]] (SaO2) < 85% in both genders.<ref name="pmid20586602">{{cite journal| author=West JB| title=English translation of "Nomenclature, classification, and diagnostic criteria of high altitude disease in China". | journal=High Alt Med Biol | year= 2010 | volume= 11 | issue= 2 | pages= 169-72 | pmid=20586602 | doi=10.1089/ham.2010.1014 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20586602 }} </ref> | Chronic mountain sickness (CMS) is characterized by [[polycythemia]] (increased [[hematocrit]]) and [[hypoxemia]] which both decrease on descent from altitude. CMS is believed to arise because of an excessive production of [[red blood cell]]s, which increases the oxygen carrying capacity of the blood but may cause increased blood viscosity and uneven blood flow through the lungs ([[V/Q mismatch]]). However, CMS is also considered an adaptation of pulmonary and [[heart disease]] to life under chronic [[hypoxia]] at altitude.<ref name="pmid17072074">{{cite journal| author=Zubieta-Castillo G, Zubieta-Calleja GR, Zubieta-Calleja L| title=Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia. | journal=J Physiol Pharmacol | year= 2006 | volume= 57 Suppl 4 | issue= | pages= 431-42 | pmid=17072074 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17072074 }} </ref> [[Clinical]] diagnosis by laboratory indicators have ranges of: [[Hemoglobin|Hb]] > 200 g/L, [[Hematocrit|Hct]] > 65%, and [[arterial oxygen saturation]] (SaO2) < 85% in both genders.<ref name="pmid20586602">{{cite journal| author=West JB| title=English translation of "Nomenclature, classification, and diagnostic criteria of high altitude disease in China". | journal=High Alt Med Biol | year= 2010 | volume= 11 | issue= 2 | pages= 169-72 | pmid=20586602 | doi=10.1089/ham.2010.1014 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20586602 }} </ref> | ||
==Laboratory Findings== | |||
==References== | ==References== | ||
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[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
[[Category:Pulmonology]] | [[Category:Pulmonology]] | ||
[[Category:Neurology]] | [[Category:Neurology]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Chronic mountain sickness (CMS) is characterized by polycythemia (increased hematocrit) and hypoxemia which both decrease on descent from altitude. CMS is believed to arise because of an excessive production of red blood cells, which increases the oxygen carrying capacity of the blood but may cause increased blood viscosity and uneven blood flow through the lungs (V/Q mismatch). However, CMS is also considered an adaptation of pulmonary and heart disease to life under chronic hypoxia at altitude.[1] Clinical diagnosis by laboratory indicators have ranges of: Hb > 200 g/L, Hct > 65%, and arterial oxygen saturation (SaO2) < 85% in both genders.[2]
Laboratory Findings
References
- ↑ Zubieta-Castillo G, Zubieta-Calleja GR, Zubieta-Calleja L (2006). "Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia". J Physiol Pharmacol. 57 Suppl 4: 431–42. PMID 17072074.
- ↑ West JB (2010). "English translation of "Nomenclature, classification, and diagnostic criteria of high altitude disease in China"". High Alt Med Biol. 11 (2): 169–72. doi:10.1089/ham.2010.1014. PMID 20586602.