Hemolytic-uremic syndrome historical perspective: Difference between revisions
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Created page with "__NOTOC__ {{HUS}} {{CMG}} ==Overview== ==Historical Perspective== :*Described by Moschowitz in 1925 - disease with hyaline thrombi in many organs :*Pentad from 1964 case serie..." |
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==Overview== | ==Overview== | ||
==Historical Perspective== | ==Historical Perspective== | ||
:*Described by Moschowitz in 1925 - disease with hyaline thrombi in many organs | :*Described by Moschowitz in 1925 - disease with hyaline thrombi in many organs | ||
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:*When first described, >90% fatal | :*When first described, >90% fatal | ||
HUS first described in 1955 in 5 children with [[ARF]] who died with renal cortical necrosis. | HUS first described in 1955 in 5 children with [[ARF]] who died with renal cortical necrosis. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Nephrology]] | [[Category:Nephrology]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
Revision as of 17:12, 17 June 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Historical Perspective
- Described by Moschowitz in 1925 - disease with hyaline thrombi in many organs
- Pentad from 1964 case series of 271 published cases:
- Thrombocytopenia
- Microangiopathic hemolytic anemia
- Neurologic symptoms and signs
- Renal function abnormalities
- Fever
- When first described, >90% fatal
HUS first described in 1955 in 5 children with ARF who died with renal cortical necrosis.