Autoimmune lymphoproliferative syndrome overview: Difference between revisions
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{{Autoimmune lymphoproliferative syndrome}} | {{Autoimmune lymphoproliferative syndrome}} | ||
{{CMG}} David Teachey, MD [mailto:TEACHEYD@email.chop.edu] | |||
==Overview== | ==Overview== | ||
'''Autoimmune lymphoproliferative syndrome''' is a form of [[lymphoproliferative disorder]]. It affects [[lymphocyte]] [[apoptosis]].<ref name="pmid18193364">{{cite journal |author=Fleisher TA |title=The autoimmune lymphoproliferative syndrome: an experiment of nature involving lymphocyte apoptosis |journal=Immunol. Res. |volume=40 |issue=1 |pages=87–92 |year=2008 |pmid=18193364 |doi=10.1007/s12026-007-8001-1 |url=http://dx.doi.org/10.1007/s12026-007-8001-1}}</ref> Autoimmune lymphoproliferative syndrome ([[ALPS]]) is a rare disorder of abnormal [[lymphocyte]] survival caused by defective [[Fas]] mediated [[apoptosis]].<ref name="pmid16522544">{{cite journal| author=Rao VK, Straus SE| title=Causes and consequences of the autoimmune lymphoproliferative syndrome. | journal=Hematology | year= 2006 | volume= 11 | issue= 1 | pages= 15-23 | pmid=16522544 | doi=10.1080/10245330500329094 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16522544 }} </ref> | '''Autoimmune lymphoproliferative syndrome''' is a form of [[lymphoproliferative disorder]]. It affects [[lymphocyte]] [[apoptosis]].<ref name="pmid18193364">{{cite journal |author=Fleisher TA |title=The autoimmune lymphoproliferative syndrome: an experiment of nature involving lymphocyte apoptosis |journal=Immunol. Res. |volume=40 |issue=1 |pages=87–92 |year=2008 |pmid=18193364 |doi=10.1007/s12026-007-8001-1 |url=http://dx.doi.org/10.1007/s12026-007-8001-1}}</ref> Autoimmune lymphoproliferative syndrome ([[ALPS]]) is a rare disorder of abnormal [[lymphocyte]] survival caused by defective [[Fas]] mediated [[apoptosis]].<ref name="pmid16522544">{{cite journal| author=Rao VK, Straus SE| title=Causes and consequences of the autoimmune lymphoproliferative syndrome. | journal=Hematology | year= 2006 | volume= 11 | issue= 1 | pages= 15-23 | pmid=16522544 | doi=10.1080/10245330500329094 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16522544 }} </ref> | ||
==Historical Perspective== | |||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
==Differentiating [Disease] from Other Diseases== | |||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Screening== | |||
==Natural History, Complications, and Prognosis== | |||
===Natural History=== | |||
===Complications=== | |||
===Prognosis=== | |||
==Diagnosis== | |||
===Diagnostic Criteria=== | |||
===History and Symptoms=== | |||
===Physical Examination=== | |||
===Laboratory Findings=== | |||
===Imaging Findings=== | |||
===Other Diagnostic Studies=== | |||
==Treatment== | |||
===Medical Therapy=== | |||
===Surgery=== | |||
===Prevention=== | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] David Teachey, MD [2]
Overview
Autoimmune lymphoproliferative syndrome is a form of lymphoproliferative disorder. It affects lymphocyte apoptosis.[1] Autoimmune lymphoproliferative syndrome (ALPS) is a rare disorder of abnormal lymphocyte survival caused by defective Fas mediated apoptosis.[2]
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating [Disease] from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
References
- ↑ Fleisher TA (2008). "The autoimmune lymphoproliferative syndrome: an experiment of nature involving lymphocyte apoptosis". Immunol. Res. 40 (1): 87–92. doi:10.1007/s12026-007-8001-1. PMID 18193364.
- ↑ Rao VK, Straus SE (2006). "Causes and consequences of the autoimmune lymphoproliferative syndrome". Hematology. 11 (1): 15–23. doi:10.1080/10245330500329094. PMID 16522544.