Polyarteritis nodosa laboratory findings: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Polyarteritis nodosa}} | {{Polyarteritis nodosa}} | ||
{{CMG}}; | {{CMG}}; {{AE}} {{CZ}}; [[User:Haritha|Haritha Machavarapu, M.B.B.S.]] | ||
==Overview== | ==Overview== | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
There are no specific lab tests for diagnosing polyarteritis nodosa. Diagnosis is generally based upon the physical examination and a few laboratory studies that help to confirm the diagnosis: | There are no specific lab tests for diagnosing polyarteritis nodosa. Diagnosis is generally based upon the physical examination and a few laboratory studies that help to confirm the diagnosis: | ||
===Electrolyte and Biomarker Studies=== | |||
* [[Complete blood count|CBC]] (may demonstrate an elevated white blood count) | * [[Complete blood count|CBC]] (may demonstrate an elevated white blood count) | ||
* [[Erythrocyte sedimentation rate|ESR]] (often elevated) | * [[Erythrocyte sedimentation rate|ESR]] (often elevated) | ||
* Perinuclear pattern of [[antineutrophil cytoplasmic antibodies]] ([[p-ANCA]]) - not associated with "classic" polyarteritis nodosa, but is present in a form of the disease affecting smaller blood vessels, known as [[microscopic polyangiitis]] or leukocytoclastic angiitis. | * Perinuclear pattern of [[antineutrophil cytoplasmic antibodies]] ([[p-ANCA]]) - not associated with "classic" polyarteritis nodosa, but is present in a form of the disease affecting smaller blood vessels, known as [[microscopic polyangiitis]] or leukocytoclastic angiitis. | ||
* Elevated [[c reactive protein]] | * Elevated [[c reactive protein]] | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 19:43, 29 June 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Haritha Machavarapu, M.B.B.S.
Overview
Laboratory Findings
There are no specific lab tests for diagnosing polyarteritis nodosa. Diagnosis is generally based upon the physical examination and a few laboratory studies that help to confirm the diagnosis:
Electrolyte and Biomarker Studies
- CBC (may demonstrate an elevated white blood count)
- ESR (often elevated)
- Perinuclear pattern of antineutrophil cytoplasmic antibodies (p-ANCA) - not associated with "classic" polyarteritis nodosa, but is present in a form of the disease affecting smaller blood vessels, known as microscopic polyangiitis or leukocytoclastic angiitis.
- Elevated c reactive protein