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==History and Symptoms==
==History and Symptoms==
*Inherited thrombophilias should be suspected in following clinical presentations<ref name=?>DeLoughery TG. Hemostasis and Thrombosis: Springer International Publishing; 2014.</ref>:  
*Inherited thrombophilias should be suspected in following clinical presentations, and, therefore, may benefit from [[Thrombophilia_laboratory_findings|thrombophilia screening]]<ref name=?>DeLoughery TG. Hemostasis and Thrombosis: Springer International Publishing; 2014.</ref>:  
**Family history of thrombosis, especially at an early age
**Family history of thrombosis, especially at an early age (< 45 years)
**Unprovoked thrombosis at an early age (<40-55 for venous thrombosis and <50-55 for arterial thrombosis)
**Unprovoked thrombosis at an early age (<40-55 for venous thrombosis and <50-55 for arterial thrombosis)
**Recurrent thrombosis
**Recurrent thrombosis
**Thrombosis at multiple sites, or unusual locations including in cerebral, splanchnic, and renal veins.
**Thrombosis at multiple sites, or unusual locations including in cerebral, hepatic, portal, mesenteric, and renal veins.
**Thrombosis in arteries with the abscence of arterial disease  
**Thrombosis in arteries with the abscence of arterial disease  
**History of fetal loss  
**History of fetal loss
**History of [[Warfarin_necrosis|warfarin skin necrosis]]


==References==
==References==

Revision as of 04:54, 30 June 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Asiri Ediriwickrema, M.D., M.H.S. [2]

Overview

History and Symptoms

  • Inherited thrombophilias should be suspected in following clinical presentations, and, therefore, may benefit from thrombophilia screening[1]:
    • Family history of thrombosis, especially at an early age (< 45 years)
    • Unprovoked thrombosis at an early age (<40-55 for venous thrombosis and <50-55 for arterial thrombosis)
    • Recurrent thrombosis
    • Thrombosis at multiple sites, or unusual locations including in cerebral, hepatic, portal, mesenteric, and renal veins.
    • Thrombosis in arteries with the abscence of arterial disease
    • History of fetal loss
    • History of warfarin skin necrosis

References

  1. DeLoughery TG. Hemostasis and Thrombosis: Springer International Publishing; 2014.

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