Thrombophilia medical therapy: Difference between revisions
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{{Thrombophilia}} | {{Thrombophilia}} | ||
{{CMG}} | {{CMG}} {{asiri}} | ||
==Overview== | ==Overview== | ||
*The [[Thrombophilia_medical_therapy|treatment]] for thrombophilia depends on the underlying hypercoagulable state and the clinical presentation. | |||
*Treatment should be tailored to the individual patient. | |||
** The risks and benefits, required monitoring, and costs associated with each form of anticoagulation should be discussed with the patient prior to initiation of therapy. | |||
*The mainstay of therapy for thrombophilia is [[anticoagulation]] with either [[warfarin]], [[Low_molecular_weight_heparin|low molecular weight heparin]], [[Direct_Xa_inhibitor|direct Xa inhibitors]], or [[Direct_thrombin_inhibitor|direct thrombin inhibitors]]. | |||
*Response to anticoagulation can be monitored clinically, or with repeat ultrasongraphy for [[Deep_vein_thrombosis|deep vein thrombosis]] or measuring [[D-dimer]] levels after treatment. | |||
==Medical Therapy== | ==Medical Therapy== | ||
The treatment | The treatment algorithms for various thrombophilias are presented below: | ||
[[Image: Thrombophilia_Management_Thrombosis.jpg|thumb|center|500px|Management of acute thrombosis in patients with inherited thrombophilias]] | |||
[[Image: Thrombophilia_Inherited_Management.jpg|thumb|center|500px|Management of asymptomatic patients with inherited thrombophilias]] | |||
[[Image: Thrombophilia_Acquired_Management.jpg|thumb|center|500px|Management of patients with acquired thrombophilias]] | |||
*'''Prophylactic anticoagulation''' should be used in the following scenarios: | |||
**Post surgery | |||
**Pregnancy and Postpartum | |||
==References== | ==References== |
Revision as of 22:37, 30 June 2016
Thrombophilia Microchapters |
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Risk calculators and risk factors for Thrombophilia medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Asiri Ediriwickrema, M.D., M.H.S. [2]
Overview
- The treatment for thrombophilia depends on the underlying hypercoagulable state and the clinical presentation.
- Treatment should be tailored to the individual patient.
- The risks and benefits, required monitoring, and costs associated with each form of anticoagulation should be discussed with the patient prior to initiation of therapy.
- The mainstay of therapy for thrombophilia is anticoagulation with either warfarin, low molecular weight heparin, direct Xa inhibitors, or direct thrombin inhibitors.
- Response to anticoagulation can be monitored clinically, or with repeat ultrasongraphy for deep vein thrombosis or measuring D-dimer levels after treatment.
Medical Therapy
The treatment algorithms for various thrombophilias are presented below:
- Prophylactic anticoagulation should be used in the following scenarios:
- Post surgery
- Pregnancy and Postpartum