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==Risk Factors== | ==Risk Factors== | ||
The most potent risk factor in the development of ARDS is [[chronic alcoholism]].<ref name="pmid8531287">{{cite journal| author=Moss M, Bucher B, Moore FA, Moore EE, Parsons PE| title=The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults. | journal=JAMA | year= 1996 | volume= 275 | issue= 1 | pages= 50-4 | pmid=8531287 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8531287 }} </ref><ref name="pmid12682442">{{cite journal| author=Moss M, Burnham EL| title=Chronic alcohol abuse, acute respiratory distress syndrome, and multiple organ dysfunction. | journal=Crit Care Med | year= 2003 | volume= 31 | issue= 4 Suppl | pages= S207-12 | pmid=12682442 | doi=10.1097/01.CCM.0000057845.77458.25 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12682442 }} </ref> Other risk factors include:<ref name="pmid11008971">{{cite journal| author=Mangialardi RJ, Martin GS, Bernard GR, Wheeler AP, Christman BW, Dupont WD et al.| title=Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis. Ibuprofen in Sepsis Study Group. | journal=Crit Care Med | year= 2000 | volume= 28 | issue= 9 | pages= 3137-45 | pmid=11008971 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11008971 }} </ref> | The most potent risk factor in the development of ARDS is [[chronic alcoholism]].<ref name="pmid8531287">{{cite journal| author=Moss M, Bucher B, Moore FA, Moore EE, Parsons PE| title=The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults. | journal=JAMA | year= 1996 | volume= 275 | issue= 1 | pages= 50-4 | pmid=8531287 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8531287 }} </ref><ref name="pmid12682442">{{cite journal| author=Moss M, Burnham EL| title=Chronic alcohol abuse, acute respiratory distress syndrome, and multiple organ dysfunction. | journal=Crit Care Med | year= 2003 | volume= 31 | issue= 4 Suppl | pages= S207-12 | pmid=12682442 | doi=10.1097/01.CCM.0000057845.77458.25 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12682442 }} </ref> Other risk factors include:<ref name="pmid11008971">{{cite journal| author=Mangialardi RJ, Martin GS, Bernard GR, Wheeler AP, Christman BW, Dupont WD et al.| title=Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis. Ibuprofen in Sepsis Study Group. | journal=Crit Care Med | year= 2000 | volume= 28 | issue= 9 | pages= 3137-45 | pmid=11008971 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11008971 }} </ref><ref>Hudson, L. D., J. A. Milberg, D. Anardi, and R. J. Maunder. “Clinical Risks for Development of the Acute Respiratory Distress Syndrome.” American Journal of Respiratory and Critical Care Medicine 151, no. 2 Pt 1 (February 1995): 293–301. doi:10.1164/ajrccm.151.2.7842182.</ref> | ||
*[[Advanced age]] | *[[Advanced age]] | ||
* [[Alcoholic liver disease]] | * [[Alcoholic liver disease]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Brian Shaller, M.D. [2]
Overview
The most potent risk factor in the development of ARDS is chronic alcoholism.[1][2] Other risk factors include advanced age, cigarette smoke exposure, and chronic liver disease.
Risk Factors
The most potent risk factor in the development of ARDS is chronic alcoholism.[1][2] Other risk factors include:[3][4]
- Advanced age
- Alcoholic liver disease
- History of prior lung disease (chronic obstructive pulmonary disease, interstitial lung disease, etc.)
- Unexplained hypotension (systolic blood pressure < 90 mm Hg for > 2 hours)
- Low systemic vascular resistance (< 800 dynes/s/cm5)
- Metabolic acidosis with anion gap > 20 mEq/L or base deficit > 5 mEq/L
- Chronic kidney disease
- Cigarette smoke exposure
- Hypoalbuminemia
- HIV
- Organ transplantation
References
- ↑ 1.0 1.1 Moss M, Bucher B, Moore FA, Moore EE, Parsons PE (1996). "The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults". JAMA. 275 (1): 50–4. PMID 8531287.
- ↑ 2.0 2.1 Moss M, Burnham EL (2003). "Chronic alcohol abuse, acute respiratory distress syndrome, and multiple organ dysfunction". Crit Care Med. 31 (4 Suppl): S207–12. doi:10.1097/01.CCM.0000057845.77458.25. PMID 12682442.
- ↑ Mangialardi RJ, Martin GS, Bernard GR, Wheeler AP, Christman BW, Dupont WD; et al. (2000). "Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis. Ibuprofen in Sepsis Study Group". Crit Care Med. 28 (9): 3137–45. PMID 11008971.
- ↑ Hudson, L. D., J. A. Milberg, D. Anardi, and R. J. Maunder. “Clinical Risks for Development of the Acute Respiratory Distress Syndrome.” American Journal of Respiratory and Critical Care Medicine 151, no. 2 Pt 1 (February 1995): 293–301. doi:10.1164/ajrccm.151.2.7842182.