Thrombophilia risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
The most common risk factors in the development of acquired thrombophlias are trauma, surgery, immobility, pregnancy, estrogen therapy, and age. The most common risk factors in the development of inherited thrombophilias are genetic mutations in factor V leiden and prothrombon G20210A. Inherited thrombophilias should be suspected in certain [[Thrombophilia_history_and_symptoms|clinical presentations]]. Refer to the [[Thrombophilia_classification|thrombophilia classification]] page for a list conditions associated with acquired thrombophilias, and to the page on [[Thrombophilia_causes|causes of thrombophilia by organ system]]. | |||
==Risk Factors== | ==Risk Factors== | ||
* Inherited thrombophilias should be suspected in certain [[Thrombophilia_history_and_symptoms|clinical presentations]] | *The most common risk factors in the development of acquired thrombophlias are the following: | ||
* Refer to the [[Thrombophilia_classification|thrombophilia classification]] page for a list conditions associated with acquired thrombophilias, and to the page on [[Thrombophilia_causes|causes of thrombophilia by organ system]] | **Trauma | ||
**Surgery | |||
**Immobility | |||
**Age | |||
**Hormones | |||
***Pregnancy | |||
***[[Oral_contraceptive|Oral contraceptive pills]] | |||
***[[Hormone_replacement_therapy|Hormone therapy]] | |||
* Inherited thrombophilias should be suspected in certain [[Thrombophilia_history_and_symptoms|clinical presentations]]<ref name="pmid24421360">{{cite journal| author=Cohoon KP, Heit JA| title=Inherited and secondary thrombophilia. | journal=Circulation | year= 2014 | volume= 129 | issue= 2 | pages= 254-7 | pmid=24421360 | doi=10.1161/CIRCULATIONAHA.113.001943 | pmc=3979345 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24421360 }} </ref><ref name="pmid11309638">{{cite journal| author=Seligsohn U, Lubetsky A| title=Genetic susceptibility to venous thrombosis. | journal=N Engl J Med | year= 2001 | volume= 344 | issue= 16 | pages= 1222-31 | pmid=11309638 | doi=10.1056/NEJM200104193441607 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11309638 }} </ref><ref name="pmid21340752">{{cite journal| author=Middeldorp S| title=Evidence-based approach to thrombophilia testing. | journal=J Thromb Thrombolysis | year= 2011 | volume= 31 | issue= 3 | pages= 275-81 | pmid=21340752 | doi=10.1007/s11239-011-0572-y | pmc=3056012 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21340752 }} </ref> | |||
* Refer to the [[Thrombophilia_classification|thrombophilia classification]] page for a list conditions associated with acquired thrombophilias, and to the page on [[Thrombophilia_causes|causes of thrombophilia by organ system]] | |||
==References== | ==References== | ||
Revision as of 17:27, 18 July 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Asiri Ediriwickrema, M.D., M.H.S. [2]
Overview
The most common risk factors in the development of acquired thrombophlias are trauma, surgery, immobility, pregnancy, estrogen therapy, and age. The most common risk factors in the development of inherited thrombophilias are genetic mutations in factor V leiden and prothrombon G20210A. Inherited thrombophilias should be suspected in certain clinical presentations. Refer to the thrombophilia classification page for a list conditions associated with acquired thrombophilias, and to the page on causes of thrombophilia by organ system.
Risk Factors
- The most common risk factors in the development of acquired thrombophlias are the following:
- Trauma
- Surgery
- Immobility
- Age
- Hormones
- Pregnancy
- Oral contraceptive pills
- Hormone therapy
- Inherited thrombophilias should be suspected in certain clinical presentations[1][2][3]
- Refer to the thrombophilia classification page for a list conditions associated with acquired thrombophilias, and to the page on causes of thrombophilia by organ system
References
- ↑ Cohoon KP, Heit JA (2014). "Inherited and secondary thrombophilia". Circulation. 129 (2): 254–7. doi:10.1161/CIRCULATIONAHA.113.001943. PMC 3979345. PMID 24421360.
- ↑ Seligsohn U, Lubetsky A (2001). "Genetic susceptibility to venous thrombosis". N Engl J Med. 344 (16): 1222–31. doi:10.1056/NEJM200104193441607. PMID 11309638.
- ↑ Middeldorp S (2011). "Evidence-based approach to thrombophilia testing". J Thromb Thrombolysis. 31 (3): 275–81. doi:10.1007/s11239-011-0572-y. PMC 3056012. PMID 21340752.