Euthyroid sick syndrome: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{SI}} | |||
{{CMG}}; {{AE}} | |||
{{SK}} Euthyroid sick syndrome; sick euthyroid syndrome; non-thyroidal illness syndrome; low T3 low T4 syndrome | |||
{{Infobox_Disease | | {{Infobox_Disease | | ||
Name = {{PAGENAME}} | | Name = {{PAGENAME}} | | ||
| Line 12: | Line 17: | ||
MeshID = D005067 | | MeshID = D005067 | | ||
}} | }} | ||
==Overview== | ==Overview== | ||
'''Euthyroid sick syndrome''' is a [[thyroid hormone]] disorder where the levels of T3 and/or T4 are at unusual levels, but the [[thyroid gland]] does not appear to be dysfunctional. | '''Euthyroid sick syndrome''' is a [[thyroid hormone]] disorder where the levels of T3 and/or T4 are at unusual levels, but the [[thyroid gland]] does not appear to be dysfunctional. | ||
==Historical Perspective== | |||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
== | ==Differentiating {{PAGENAME}} from Other Diseases== | ||
[[Fasting]], [[starvation]], [[sepsis]], [[Physical trauma|trauma]], [[cardiopulmonary bypass]], [[malignancy]], [[heart failure]], [[hypothermia]], [[myocardial infarction]], [[chronic renal failure]], [[cirrhosis]], and [[diabetic ketoacidosis]]. | [[Fasting]], [[starvation]], [[sepsis]], [[Physical trauma|trauma]], [[cardiopulmonary bypass]], [[malignancy]], [[heart failure]], [[hypothermia]], [[myocardial infarction]], [[chronic renal failure]], [[cirrhosis]], and [[diabetic ketoacidosis]]. | ||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Screening== | |||
==Natural History, Complications, and Prognosis== | |||
===Natural History=== | |||
===Complications=== | |||
===Prognosis=== | |||
==Diagnosis== | ==Diagnosis== | ||
===Diagnostic Criteria=== | |||
===History and Symptoms=== | |||
===Physical Examination=== | |||
===Laboratory Findings=== | |||
===Imaging Findings=== | |||
===Other Diagnostic Studies=== | |||
==Treatment== | |||
===Medical Therapy=== | |||
Ill patients may have normal to low TSH depending on the spectrum of illness. Total T4 and T3 levels may be altered by [[binding protein]] abnormalities, and medications. [[Reverse T3]] are generally increased signifying inhibition of normal Type 1 enzyme or reduced clearance of reverse T3. Measurement of free T4 and/or free T3 levels will be normal. | Ill patients may have normal to low TSH depending on the spectrum of illness. Total T4 and T3 levels may be altered by [[binding protein]] abnormalities, and medications. [[Reverse T3]] are generally increased signifying inhibition of normal Type 1 enzyme or reduced clearance of reverse T3. Measurement of free T4 and/or free T3 levels will be normal. | ||
== | |||
===Surgery=== | |||
===Prevention=== | |||
==External links== | ==External links== | ||
* {{cite journal |author=McIver B, Gorman C |title=Euthyroid sick syndrome: an overview |journal=Thyroid |volume=7 |issue=1 |pages=125-32 |year=1997 |pmid=9086580}} | * {{cite journal |author=McIver B, Gorman C |title=Euthyroid sick syndrome: an overview |journal=Thyroid |volume=7 |issue=1 |pages=125-32 |year=1997 |pmid=9086580}} | ||
{{Endocrine pathology}} | {{Endocrine pathology}} | ||
==References== | |||
{{reflist|2}} | |||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 18:20, 22 July 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Synonyms and keywords: Euthyroid sick syndrome; sick euthyroid syndrome; non-thyroidal illness syndrome; low T3 low T4 syndrome
| Euthyroid sick syndrome | |
| ICD-10 | E07.8 |
|---|---|
| ICD-9 | 790.94 |
| MeSH | D005067 |
Overview
Euthyroid sick syndrome is a thyroid hormone disorder where the levels of T3 and/or T4 are at unusual levels, but the thyroid gland does not appear to be dysfunctional.
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Euthyroid sick syndrome from Other Diseases
Fasting, starvation, sepsis, trauma, cardiopulmonary bypass, malignancy, heart failure, hypothermia, myocardial infarction, chronic renal failure, cirrhosis, and diabetic ketoacidosis.
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Ill patients may have normal to low TSH depending on the spectrum of illness. Total T4 and T3 levels may be altered by binding protein abnormalities, and medications. Reverse T3 are generally increased signifying inhibition of normal Type 1 enzyme or reduced clearance of reverse T3. Measurement of free T4 and/or free T3 levels will be normal.
Surgery
Prevention
External links
- McIver B, Gorman C (1997). "Euthyroid sick syndrome: an overview". Thyroid. 7 (1): 125–32. PMID 9086580.