Adrenoleukodystrophy medical therapy: Difference between revisions
Created page with "__NOTOC__ {{Adrenoleukodystrophy}} {{CMG}} ==Overview== ==Medical Therapy== While there is currently no cure for the disease, some dietary treatments, for example, [[Lorenzo's..." |
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__NOTOC__ | __NOTOC__ | ||
{{Adrenoleukodystrophy}} | {{Adrenoleukodystrophy}} | ||
{{CMG}} | {{CMG}}; {{AE}} | ||
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==Overview== | ==Overview== | ||
==Medical Therapy== | ==Medical Therapy== | ||
While there is currently no cure for the disease, some dietary treatments, for example, [[Lorenzo's oil]] in combination with a diet low in VLCFA, have been used with limited success, especially before disease symptoms appear. A recent study by Moser ''et al'' (2005) shows positive long-term results with this approach;<ref>Moser HW, Raymond GV, Lu S-E, Muenz LR, Moser AB, Xu J, Jones RO, Loes DJ, Melhem ER, Dubey P, Bezman L, Brereton NH, Odone A. ''Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's Oil.'' Arch Neurol 2005;62;1073-80. PMID 16009761.</ref> see also [[the Myelin Project]]. | While there is currently no cure for the disease, some dietary treatments, for example, [[Lorenzo's oil]] in combination with a diet low in VLCFA, have been used with limited success, especially before disease symptoms appear. A recent study by Moser ''et al'' (2005) shows positive long-term results with this approach;<ref>Moser HW, Raymond GV, Lu S-E, Muenz LR, Moser AB, Xu J, Jones RO, Loes DJ, Melhem ER, Dubey P, Bezman L, Brereton NH, Odone A. ''Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's Oil.'' Arch Neurol 2005;62;1073-80. PMID 16009761.</ref> see also [[the Myelin Project]]. | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Endocrinology]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
Revision as of 18:39, 22 July 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
Medical Therapy
While there is currently no cure for the disease, some dietary treatments, for example, Lorenzo's oil in combination with a diet low in VLCFA, have been used with limited success, especially before disease symptoms appear. A recent study by Moser et al (2005) shows positive long-term results with this approach;[1] see also the Myelin Project.
Bone marrow transplantation has been proven to help ALD who are either presymptomatic or exhibiting mild symptoms early in the course of the disease.
Lovastatin is an anticholesterol drug that seems to help, but researchers aren't sure how or why.
Treatment, however, is to AID the symptoms and is NOT a cure.
References
- ↑ Moser HW, Raymond GV, Lu S-E, Muenz LR, Moser AB, Xu J, Jones RO, Loes DJ, Melhem ER, Dubey P, Bezman L, Brereton NH, Odone A. Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's Oil. Arch Neurol 2005;62;1073-80. PMID 16009761.