Aphthous ulcer pathophysiology: Difference between revisions
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*Systemic disease | *Systemic disease | ||
**[[Behcet disease]] | **[[Behcet disease]] | ||
** | **Mouth and genital ulcers with inflamed cartilage (MAGIC syndrome) | ||
**[[Crohn disease]] | **[[Crohn disease]] | ||
**[[Ulcerative colitis]] | **[[Ulcerative colitis]] | ||
**[[Human immunodeficiency virus]] infection | **[[Human immunodeficiency virus]] infection | ||
**[[Cyclic neutropenia]] | **[[Cyclic neutropenia]] | ||
**[[Marshall syndrome]] | |||
*Microbial | *Microbial | ||
**Bacterial ([[streptococcus|streptococci]]) | **Bacterial ([[streptococcus|streptococci]]) | ||
**Viral ([[varicella zoster]] and [[cytomegalovirus]]) | **Viral ([[varicella zoster]] and [[cytomegalovirus]]) | ||
*Genetics | *Genetics | ||
**Ethnicity | **Ethnicity | ||
Revision as of 13:39, 6 September 2016
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Aphthous ulcer Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Aphthous ulcer pathophysiology On the Web |
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American Roentgen Ray Society Images of Aphthous ulcer pathophysiology |
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Risk calculators and risk factors for Aphthous ulcer pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]
Overview
The pathophysiology of Aphthous ulcers is not fully understood. It is though that reucurren
Pathophysiology
Pathogenesis
The exact pathogenesis of aphthous ulcer in not clear. Contributing factors include:
- Allergies
- Genetic predisposition
- Hormonal influences
- Hematologic abnormalities
- Immunologic factors
- Infectious agents
- Nutritional deficiencies
- Smoking cessation
- Stress
- Trauma
It is thought that aphthous ulcer is the result of the cross reactivity between Staphylococcus sanguis and 60kDa Heat shock protein (HSP60)
It is thought aphthous ulcer is a result of is caused by either , [hypothesis 2], or [hypothesis 3].
Associated conditions
- Systemic disease
- Behcet disease
- Mouth and genital ulcers with inflamed cartilage (MAGIC syndrome)
- Crohn disease
- Ulcerative colitis
- Human immunodeficiency virus infection
- Cyclic neutropenia
- Marshall syndrome
- Microbial
- Bacterial (streptococci)
- Viral (varicella zoster and cytomegalovirus)
- Genetics
- Ethnicity
- Human leukocyte antigen haplotypes (HLA B51)
- Allergic/Immunologic
- Local T-lymphocyte cytotoxicity
- Sodium lauryl sulfate sensitivity (in tooth paste)
- Abnormal CD4/CD8 ratio
- Microbe-induced hypersensitivity
- Food sensitivity
- Others
- Antioxidants
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Beta blockers
- Immunosuppressive drugs
- Stress
- Psychological imbalance