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{{Acute bronchitis}}
{{Acute bronchitis}}
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==Overview==
==Overview==
'''Bronchitis''' is an [[inflammation]] of the large [[bronchus|bronchi]] (medium-size airways) in the [[lung]]s. It can lead to [[pneumonia]].  ''Acute bronchitis'' is usually caused by [[virus]]es or [[bacteria]] and may last several days or weeks.<ref name="pmid17108344">{{cite journal |author=Wenzel RP, Fowler AA |title=Clinical practice. Acute bronchitis |journal=N. Engl. J. Med. |volume=355 |issue=20 |pages=2125–30 |year=2006 |pmid=17108344 |doi=10.1056/NEJMcp061493}}</ref> '''Acute bronchitis''' is characterized by [[cough]] and [[sputum]] (phlegm) production and symptoms related to the obstruction of the airways by the inflamed airways and the phlegm, such as shortness of breath and wheezing. Diagnosis is by clinical examination and sometimes [[microbiology|microbiological]] examination of the phlegm. Treatment may be with [[antibiotic]]s (if a bacterial infection is suspected), [[bronchodilator]]s (to relieve breathlessness) and other treatments.
==Historical Perspective==
Acute bronchitis was first described by Charles Badham in 1808 in England<ref name="pmid19343614">{{cite journal |vauthors=Klippe HJ, Kirsten D |title=[200 years of bronchitis--from 1808 to 2008] |language=German |journal=Pneumologie |volume=63 |issue=4 |pages=228–30 |year=2009 |pmid=19343614 |doi=10.1055/s-0028-1119572 |url=}}</ref>. In 1821, Dr. Rene Laennec, known as the '''''father of chest medicine''''' described bronchitis in details<ref>terms(2016)https://lunginstitute.com/blog/history-of-chronic-bronchitis/accessed on September,13 2016</ref>
.
==Pathophysiology==
The causative agent, either viruses or bacteria transmitted via airways to the large and medium size airways tract and inoculate the epithelium that leads to inflammation, thickening, and increased mucus production in the airways<ref name="pmid11119400">{{cite journal |vauthors=Gonzales R, Sande MA |title=Uncomplicated acute bronchitis |journal=Ann. Intern. Med. |volume=133 |issue=12 |pages=981–91 |year=2000 |pmid=11119400 |doi= |url=}}</ref>.Epithelial-cell desquamation and denuding of the airway to the level of the basement membrane in association with the presence of a lymphocytic cellular infiltrate have been demonstrated on microscopic examination<ref name="pmid11119400">{{cite journal |vauthors=Gonzales R, Sande MA |title=Uncomplicated acute bronchitis |journal=Ann. Intern. Med. |volume=133 |issue=12 |pages=981–91 |year=2000 |pmid=11119400 |doi= |url=}}</ref>.
==Causes==
Common causes of acute bronchitis include viruses, Bacteria and environmental factors. Among them,[[influenza]] is the most common<ref name="pmid2174179">{{cite journal |vauthors=Boldy DA, Skidmore SJ, Ayres JG |title=Acute bronchitis in the community: clinical features, infective factors, changes in pulmonary function and bronchial reactivity to histamine |journal=Respir Med |volume=84 |issue=5 |pages=377–85 |year=1990 |pmid=2174179 |doi= |url=}}</ref><ref name="pmid17108344">{{cite journal |vauthors=Wenzel RP, Fowler AA |title=Clinical practice. Acute bronchitis |journal=N. Engl. J. Med. |volume=355 |issue=20 |pages=2125–30 |year=2006 |pmid=17108344 |doi=10.1056/NEJMcp061493 |url=}}</ref><ref name="pmid9323784">{{cite journal |vauthors=Jonsson JS, Sigurdsson JA, Kristinsson KG, Guthnadóttir M, Magnusson S |title=Acute bronchitis in adults. How close do we come to its aetiology in general practice? |journal=Scand J Prim Health Care |volume=15 |issue=3 |pages=156–60 |year=1997 |pmid=9323784 |doi= |url=}}</ref>..


==References==
==References==

Revision as of 19:34, 13 September 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

Historical Perspective

Acute bronchitis was first described by Charles Badham in 1808 in England[1]. In 1821, Dr. Rene Laennec, known as the father of chest medicine described bronchitis in details[2] .

Pathophysiology

The causative agent, either viruses or bacteria transmitted via airways to the large and medium size airways tract and inoculate the epithelium that leads to inflammation, thickening, and increased mucus production in the airways[3].Epithelial-cell desquamation and denuding of the airway to the level of the basement membrane in association with the presence of a lymphocytic cellular infiltrate have been demonstrated on microscopic examination[3].

Causes

Common causes of acute bronchitis include viruses, Bacteria and environmental factors. Among them,influenza is the most common[4][5][6]..

References

  1. Klippe HJ, Kirsten D (2009). "[200 years of bronchitis--from 1808 to 2008]". Pneumologie (in German). 63 (4): 228–30. doi:10.1055/s-0028-1119572. PMID 19343614.
  2. terms(2016)https://lunginstitute.com/blog/history-of-chronic-bronchitis/accessed on September,13 2016
  3. 3.0 3.1 Gonzales R, Sande MA (2000). "Uncomplicated acute bronchitis". Ann. Intern. Med. 133 (12): 981–91. PMID 11119400.
  4. Boldy DA, Skidmore SJ, Ayres JG (1990). "Acute bronchitis in the community: clinical features, infective factors, changes in pulmonary function and bronchial reactivity to histamine". Respir Med. 84 (5): 377–85. PMID 2174179.
  5. Wenzel RP, Fowler AA (2006). "Clinical practice. Acute bronchitis". N. Engl. J. Med. 355 (20): 2125–30. doi:10.1056/NEJMcp061493. PMID 17108344.
  6. Jonsson JS, Sigurdsson JA, Kristinsson KG, Guthnadóttir M, Magnusson S (1997). "Acute bronchitis in adults. How close do we come to its aetiology in general practice?". Scand J Prim Health Care. 15 (3): 156–60. PMID 9323784.

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