Differentiating erythrasma from other diseases: Difference between revisions

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| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Dermatophytosis]]'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Dermatophytosis]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |Presents with lesions that vary based on the location of the [[mycosis]], but usually displays in a circular shape with [[erythema]], scaling, and [[itching]] at the point of infiltration .<ref name="pmid25403034">{{cite journal |vauthors=Ely JW, Rosenfeld S, Seabury Stone M |title=Diagnosis and management of tinea infections |journal=Am Fam Physician |volume=90 |issue=10 |pages=702–10 |year=2014 |pmid=25403034 |doi= |url=}}</ref> Differentiated by its [[mycosis|mycotic]] cause. Treatment involves topical [[antifungal]] medication, including [[miconazole]], [[clotrimazole]], [[ketoconazole]], [[terbinafine]], [[naftifine]], and [[butenafine]].<ref name="pmid15663341">{{cite journal |vauthors=Kyle AA, Dahl MV |title=Topical therapy for fungal infections |journal=Am J Clin Dermatol |volume=5 |issue=6 |pages=443–51 |year=2004 |pmid=15663341 |doi= |url=}}</ref>  
| style="padding: 5px 5px; background: #F5F5F5;" |Presents with lesions that vary based on the location of the [[mycosis]], but usually displays in a circular shape with [[erythema]], scaling, and [[itching]] at the point of infiltration .<ref name="pmid25403034">{{cite journal |vauthors=Ely JW, Rosenfeld S, Seabury Stone M |title=Diagnosis and management of tinea infections |journal=Am Fam Physician |volume=90 |issue=10 |pages=702–10 |year=2014 |pmid=25403034 |doi= |url=}}</ref> Differentiated by its [[mycosis|mycotic]] cause. Visually distinct from Erythrasma by consistently forming circular-shaped "ring" [[lesions]]. Treatment involves topical [[antifungal]] medication, including [[miconazole]], [[clotrimazole]], [[ketoconazole]], [[terbinafine]], [[naftifine]], and [[butenafine]].<ref name="pmid15663341">{{cite journal |vauthors=Kyle AA, Dahl MV |title=Topical therapy for fungal infections |journal=Am J Clin Dermatol |volume=5 |issue=6 |pages=443–51 |year=2004 |pmid=15663341 |doi= |url=}}</ref>  
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| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Candidiasis]]'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''Skin [[Candidiasis]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |Presents with [[rash]] that displays [[erythema]] and [[itching]], as well as [[folliculitis]].<ref name="urlGenital / vulvovaginal candidiasis (VVC) | Fungal Diseases | CDC">{{cite web |url=https://www.cdc.gov/fungal/diseases/candidiasis/genital/index.html |title=Genital / vulvovaginal candidiasis (VVC) &#124; Fungal Diseases &#124; CDC |format= |work= |accessdate=}}</ref> Differentiated from Erythrasma in that it is caused by ''[[Candida]]'' [[fungal]] infection. While Erythrasma usually manifests in moist locations, such as skin folds, skin [[candidiasis]] is usually found in wet or dry regions of the body. Treatment includes [[antifungal]] therapy, including [[fluconazole]], [[caspofungin]], [[micafungin]], [[anidulafungin]], and additional topical and systemic options.<ref name="PappasKauffman2009">{{cite journal|last1=Pappas|first1=Peter G.|last2=Kauffman|first2=Carol A.|last3=Andes|first3=David|last4=Benjamin, Jr.|first4=Daniel K.|last5=Calandra|first5=Thierry F.|last6=Edwards, Jr.|first6=John E.|last7=Filler|first7=Scott G.|last8=Fisher|first8=John F.|last9=Kullberg|first9=Bart‐Jan|last10=Ostrosky‐Zeichner|first10=Luis|last11=Reboli|first11=Annette C.|last12=Rex|first12=John H.|last13=Walsh|first13=Thomas J.|last14=Sobel|first14=Jack D.|title=Clinical Practice Guidelines for the Management of Candidiasis: 2009 Update by the Infectious Diseases Society of America|journal=Clinical Infectious Diseases|volume=48|issue=5|year=2009|pages=503–535|issn=1058-4838|doi=10.1086/596757}}</ref>
 
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| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Intertrigo]]'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Intertrigo]]'''
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| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Contact dermatitis]]'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Contact dermatitis]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |An [[inflammatory]] condition of the [[epidermis]] resulting from direct contact with an [[allergen]] or [[irritant]]. Contact dermatitis is similar to erysipelas due to the usual presentation of [[erythema]], [[blisters]], [[itching]], [[pain]], and [[discharge]]. Differentiated from erysipelas by its cause: an [[allergic]] response by contact to a specific surface or entity. There is no indication of [[bacterial]] infection. Common causes include chemicals from cosmetic and hygienic products, fabrics, metals, and animal [[hair]] or [[skin]]. Therapy involves avoiding the original cause and application of topical or oral [[corticosteroids]] and [[analgesics]].<ref name="urlContact dermatitis: MedlinePlus Medical Encyclopedia">{{cite web |url=https://medlineplus.gov/ency/article/000869.htm |title=Contact dermatitis: MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref>
| style="padding: 5px 5px; background: #F5F5F5;" |An [[inflammatory]] condition of the [[epidermis]] resulting from direct contact with an [[allergen]] or [[irritant]]. Contact dermatitis is similar to Erythrasma due to the usual presentation of [[erythema]] and [[itching]]. It differentiates from Erythrasma by manifesting with [[blisters]], [[pain]], and [[discharge]]. Differentiated from Erythrasma by its cause: an [[allergic]] response by contact to a specific surface or entity. There is no indication of [[bacterial]] infection. Common causes include chemicals from cosmetic and hygienic products, fabrics, metals, and animal [[hair]] or [[skin]]. Therapy involves avoiding the original cause and application of topical or oral [[corticosteroids]] and [[analgesics]].<ref name="urlContact dermatitis: MedlinePlus Medical Encyclopedia">{{cite web |url=https://medlineplus.gov/ency/article/000869.htm |title=Contact dermatitis: MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref>


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Revision as of 15:33, 30 September 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Erythrasma must be differentiated from other dermatological conditions that present with pain, erythema, edema, and blisters of the skin, as well as other systemic conditions such as fever, chills, fatigue, headache, and vomiting.

Differentiating Erythrasma from other Diseases

Erythrasma must be differentiated from other dermatological conditions that present with reddish-brown scales and [[itching], as well as other diseases resulting from corynebacteria infection.

Disease Findings
Psoriasis Presents with erythema and formation of silvery scales on the epidermis, resulting in itching and pain.[1] Differentiates from Erythrasma in that it is usually located throughout the entire body; Erythrasma usually manifests in skin folds of the armpit, groin, and perianal regions.[2]Psoriasis is an autoimmune disorder and is not caused by Corynebacteria; therapeutic options include topical corticosteroids, systemic anti-inflammatory therapies (such as methotrexate and cyclosporine), and UVA/UVB phototherapy.[2] Psoriasis is a chronic, recurrent condition; Erythrasma will usually resolve with sufficient treatment.
Dermatophytosis Presents with lesions that vary based on the location of the mycosis, but usually displays in a circular shape with erythema, scaling, and itching at the point of infiltration .[3] Differentiated by its mycotic cause. Visually distinct from Erythrasma by consistently forming circular-shaped "ring" lesions. Treatment involves topical antifungal medication, including miconazole, clotrimazole, ketoconazole, terbinafine, naftifine, and butenafine.[4]
Skin Candidiasis Presents with rash that displays erythema and itching, as well as folliculitis.[5] Differentiated from Erythrasma in that it is caused by Candida fungal infection. While Erythrasma usually manifests in moist locations, such as skin folds, skin candidiasis is usually found in wet or dry regions of the body. Treatment includes antifungal therapy, including fluconazole, caspofungin, micafungin, anidulafungin, and additional topical and systemic options.[6]
Intertrigo
Contact dermatitis An inflammatory condition of the epidermis resulting from direct contact with an allergen or irritant. Contact dermatitis is similar to Erythrasma due to the usual presentation of erythema and itching. It differentiates from Erythrasma by manifesting with blisters, pain, and discharge. Differentiated from Erythrasma by its cause: an allergic response by contact to a specific surface or entity. There is no indication of bacterial infection. Common causes include chemicals from cosmetic and hygienic products, fabrics, metals, and animal hair or skin. Therapy involves avoiding the original cause and application of topical or oral corticosteroids and analgesics.[7]

References

  1. "Psoriasis: MedlinePlus".
  2. 2.0 2.1 Di Meglio P, Villanova F, Nestle FO (2014). "Psoriasis". Cold Spring Harb Perspect Med. 4 (8). doi:10.1101/cshperspect.a015354. PMC 4109580. PMID 25085957.
  3. Ely JW, Rosenfeld S, Seabury Stone M (2014). "Diagnosis and management of tinea infections". Am Fam Physician. 90 (10): 702–10. PMID 25403034.
  4. Kyle AA, Dahl MV (2004). "Topical therapy for fungal infections". Am J Clin Dermatol. 5 (6): 443–51. PMID 15663341.
  5. "Genital / vulvovaginal candidiasis (VVC) | Fungal Diseases | CDC".
  6. Pappas, Peter G.; Kauffman, Carol A.; Andes, David; Benjamin, Jr., Daniel K.; Calandra, Thierry F.; Edwards, Jr., John E.; Filler, Scott G.; Fisher, John F.; Kullberg, Bart‐Jan; Ostrosky‐Zeichner, Luis; Reboli, Annette C.; Rex, John H.; Walsh, Thomas J.; Sobel, Jack D. (2009). "Clinical Practice Guidelines for the Management of Candidiasis: 2009 Update by the Infectious Diseases Society of America". Clinical Infectious Diseases. 48 (5): 503–535. doi:10.1086/596757. ISSN 1058-4838.
  7. "Contact dermatitis: MedlinePlus Medical Encyclopedia".

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