Hepatitis B vertical transmission: Difference between revisions
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==Hepatitis B vertical transmission== | ==Hepatitis B vertical transmission== | ||
Hepatitis B virus (HBV) infection in a pregnant woman poses a serious risk to her infant at birth. Without postexposure [[immunoprophylaxis]], approximately 40% of infants born to HBV-infected mothers in the United States will develop chronic HBV infection, approximately one-fourth of whom will eventually die from [[chronic liver disease]]. | |||
Perinatal HBV transmission can be prevented by identifying HBV-infected (i.e., hepatitis B surface antigen [HBsAg]-positive) pregnant women and providing hepatitis B immune globulin and hepatitis B vaccine to their infants within 12 hours of birth. | |||
*Preventing perinatal HBV transmission is an integral part of the national strategy to eliminate hepatitis B in the United States. National guidelines call for the following: | |||
**Universal screening of pregnant women for HBsAg during each pregnancy | |||
**Case management of HBsAg-positive mothers and their infants | |||
**Provision of immunoprophylaxis for infants born to infected mothers, including [[hepatitis B vaccine]] and hepatitis B [[immune globulin]] | |||
**Routine vaccination of all infants with the hepatitis B vaccine series, with the first dose administered at birth | |||
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==References == | |||
{{Reflist|2}} | |||
[[Category:Infectious disease]] | |||
[[Category:Gastroenterology]] | |||
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{{WS}} | |||
Revision as of 15:38, 5 October 2016
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Hepatitis B |
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Hepatitis B vertical transmission On the Web |
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American Roentgen Ray Society Images of Hepatitis B vertical transmission |
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Risk calculators and risk factors for Hepatitis B vertical transmission |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]
Overview
Hepatitis B vertical transmission
Hepatitis B virus (HBV) infection in a pregnant woman poses a serious risk to her infant at birth. Without postexposure immunoprophylaxis, approximately 40% of infants born to HBV-infected mothers in the United States will develop chronic HBV infection, approximately one-fourth of whom will eventually die from chronic liver disease.
Perinatal HBV transmission can be prevented by identifying HBV-infected (i.e., hepatitis B surface antigen [HBsAg]-positive) pregnant women and providing hepatitis B immune globulin and hepatitis B vaccine to their infants within 12 hours of birth.
- Preventing perinatal HBV transmission is an integral part of the national strategy to eliminate hepatitis B in the United States. National guidelines call for the following:
- Universal screening of pregnant women for HBsAg during each pregnancy
- Case management of HBsAg-positive mothers and their infants
- Provision of immunoprophylaxis for infants born to infected mothers, including hepatitis B vaccine and hepatitis B immune globulin
- Routine vaccination of all infants with the hepatitis B vaccine series, with the first dose administered at birth
[[Image: