Erythrasma laboratory findings: Difference between revisions
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===Culture=== | ===Culture=== | ||
*An [[epidermal]] swab of the affected region may provide samples of the pathogenic ''[[Corynebacterium|Corynebacterium minitissimum]]''.<ref name="pmid12010076">{{cite journal |vauthors=Holdiness MR |title=Management of cutaneous erythrasma |journal=Drugs |volume=62 |issue=8 |pages=1131–41 |year=2002 |pmid=12010076 |doi= |url=}}</ref> | *An [[epidermal]] swab of the affected region may provide samples of the pathogenic ''[[Corynebacterium|Corynebacterium minitissimum]]''.<ref name="pmid12010076">{{cite journal |vauthors=Holdiness MR |title=Management of cutaneous erythrasma |journal=Drugs |volume=62 |issue=8 |pages=1131–41 |year=2002 |pmid=12010076 |doi= |url=}}</ref> | ||
**''[[Corynebacterium|Corynebacterium | **''[[Corynebacterium|Corynebacterium minutissimum]]'' will present as non-[[hemolytic]] smooth colonies that are 1-1.5mm in size.<ref name="pmid15310342">{{cite journal |vauthors=Karakatsanis G, Vakirlis E, Kastoridou C, Devliotou-Panagiotidou D |title=Coexistence of pityriasis versicolor and erythrasma |journal=Mycoses |volume=47 |issue=7 |pages=343–5 |year=2004 |pmid=15310342 |doi=10.1111/j.1439-0507.2004.00997.x |url=}}</ref> | ||
**''[[Corynebacterium|Corynebacterium minutissimum]]'' can be distinguished from other [[serotypes]] by its lack of necessity for [[lipids]] to grow in vitro.<ref name="pmid2116939">{{cite journal |vauthors=Coyle MB, Lipsky BA |title=Coryneform bacteria in infectious diseases: clinical and laboratory aspects |journal=Clin. Microbiol. Rev. |volume=3 |issue=3 |pages=227–46 |year=1990 |pmid=2116939 |pmc=358157 |doi= |url=}}</ref> | |||
*Due to the 2-3 week incubation requirements and the low sensitivity, culture analysis is not effective as a sole diagnostic measure.<ref name="pmid25477907">{{cite journal |vauthors=Sariguzel FM, Koc AN, Yagmur G, Berk E |title=Interdigital foot infections: Corynebacterium minutissimum and agents of superficial mycoses |journal=Braz. J. Microbiol. |volume=45 |issue=3 |pages=781–4 |year=2014 |pmid=25477907 |pmc=4204958 |doi= |url=}}</ref> | *Due to the 2-3 week incubation requirements and the low sensitivity, culture analysis is not effective as a sole diagnostic measure.<ref name="pmid25477907">{{cite journal |vauthors=Sariguzel FM, Koc AN, Yagmur G, Berk E |title=Interdigital foot infections: Corynebacterium minutissimum and agents of superficial mycoses |journal=Braz. J. Microbiol. |volume=45 |issue=3 |pages=781–4 |year=2014 |pmid=25477907 |pmc=4204958 |doi= |url=}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Laboratory Findings
Culture
- An epidermal swab of the affected region may provide samples of the pathogenic Corynebacterium minitissimum.[1]
- Corynebacterium minutissimum will present as non-hemolytic smooth colonies that are 1-1.5mm in size.[2]
- Corynebacterium minutissimum can be distinguished from other serotypes by its lack of necessity for lipids to grow in vitro.[3]
- Due to the 2-3 week incubation requirements and the low sensitivity, culture analysis is not effective as a sole diagnostic measure.[4]
Gram staining
- Gram stain analysis of Corynebacterium minitissimum, a gram-positive will reveal the following:[5]
- Violet or blue coloration due to gram-positive rods reacting with the gram-stain
- Slightly curved bacterial rods[6]
References
- ↑ Holdiness MR (2002). "Management of cutaneous erythrasma". Drugs. 62 (8): 1131–41. PMID 12010076.
- ↑ Karakatsanis G, Vakirlis E, Kastoridou C, Devliotou-Panagiotidou D (2004). "Coexistence of pityriasis versicolor and erythrasma". Mycoses. 47 (7): 343–5. doi:10.1111/j.1439-0507.2004.00997.x. PMID 15310342.
- ↑ Coyle MB, Lipsky BA (1990). "Coryneform bacteria in infectious diseases: clinical and laboratory aspects". Clin. Microbiol. Rev. 3 (3): 227–46. PMC 358157. PMID 2116939.
- ↑ Sariguzel FM, Koc AN, Yagmur G, Berk E (2014). "Interdigital foot infections: Corynebacterium minutissimum and agents of superficial mycoses". Braz. J. Microbiol. 45 (3): 781–4. PMC 4204958. PMID 25477907.
- ↑ Granok, Alexander B.; Benjamin, Patti; Garrett, Lee S. (2002). "Corynebacterium minutissimumBacteremia in an Immunocompetent Host with Cellulitis". Clinical Infectious Diseases. 35 (4): e40–e42. doi:10.1086/341981. ISSN 1058-4838.
- ↑ Shin JY, Lee WK, Seo YH, Park YS (2014). "Postoperative Abdominal Infection Caused by Corynebacterium minutissimum". Infect Chemother. 46 (4): 261–3. doi:10.3947/ic.2014.46.4.261. PMC 4285009. PMID 25566407.