Diphtheria natural history, complications and prognosis: Difference between revisions
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{{Diphtheria}} | {{Diphtheria}} | ||
{{CMG}} {{AE}} {{KD}} | {{CMG}} {{AE}} {{KD}} {{AA}} | ||
==Overview== | ==Overview== | ||
Diphtheria is a vaccine preventable disease which can lead to severe complications like respiratory failure, myocarditis, polyneuropathies and death once the disease sets in. | Diphtheria is a vaccine preventable disease which can lead to severe complications like respiratory failure, myocarditis, polyneuropathies and death once the disease sets in. | ||
==Natural history== | |||
==Complications== | ==Complications== | ||
* [[Respiratory failure]] | Complications that can develop as a result of diphtheria are:<ref name=CDCdiphtheria>http://www.cdc.gov/diphtheria/about/complications.html Accessed on October 7, 2016</ref> | ||
* [[Myocarditis]] | * [[Respiratory failure]] | ||
* [[Polyneuropathies]] | * [[Myocarditis]] | ||
* [[Polyneuropathies]] | |||
** 10th cranial nerve disorder | ** 10th cranial nerve disorder | ||
** 9th cranial nerve disorder | ** 9th cranial nerve disorder | ||
** [[Peripheral motor neuropathy]] | ** [[Peripheral motor neuropathy]] | ||
* [[Acute renal failure ]] | * [[Acute renal failure ]] | ||
* [[Death]] | * [[Death]] | ||
==Prognosis== | ==Prognosis== | ||
*The overall case-fatality rate for diphtheria is 5%–10%, with higher death rates (up to 20%) among persons younger than 5 and older than 40 years of age. The case-fatality rate for diphtheria has changed very little during the last 50 years. | |||
* The disease can be prevented by vaccines. However, the prognosis is not good once the disease sets in. | * The disease can be prevented by vaccines. However, the prognosis is not good once the disease sets in. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Gastroenterology]] | ||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 18:35, 7 October 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2] Aysha Anwar, M.B.B.S[3]
Overview
Diphtheria is a vaccine preventable disease which can lead to severe complications like respiratory failure, myocarditis, polyneuropathies and death once the disease sets in.
Natural history
Complications
Complications that can develop as a result of diphtheria are:[1]
- Respiratory failure
- Myocarditis
- Polyneuropathies
- 10th cranial nerve disorder
- 9th cranial nerve disorder
- Peripheral motor neuropathy
- Acute renal failure
- Death
Prognosis
- The overall case-fatality rate for diphtheria is 5%–10%, with higher death rates (up to 20%) among persons younger than 5 and older than 40 years of age. The case-fatality rate for diphtheria has changed very little during the last 50 years.
- The disease can be prevented by vaccines. However, the prognosis is not good once the disease sets in.
References
- ↑ http://www.cdc.gov/diphtheria/about/complications.html Accessed on October 7, 2016