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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]
Ovrview
In 1892, the hypothesis that bacterial flora may be a cause of vaginal infectious conditions was first described by Albert Döderlein. In 1955, Gardnerella vaginalis was named as a new genus as the cause of the foul-smelling watery vaginal discharge by Gardner and Dukes.[1][2]
Historical perspective
- In 1780, a gram-positive facultative anaerobic bacteria, Lactobacillus spp., was first discovered in sour milk by Scheele,
- in 1858, Lactobacillus spp. subsequently was discovered in humans by Folwarczny.
- In 1892, the hypothesis that bacterial flora may be a cause of vaginal infectious conditions was first described by Albert Döderlein,
- In 1921, three lactobacillary grades was developed by by Schröder.[1]
- Up to the 1950s, the exact etiology of lactobacillary deficiency was still uncertain, and symptomatic women with lactobacillary grade III were diagnosed with vaginitis.
- In 1955, the newly discovered bacterium (‘Haemophilus vaginalis’) was first named by Gardner and Dukes. They thought their newly discovered bacterium belonged to the Haemophilus group, but soon afterwards Gardnerella vaginalis was named as a new genus as the cause of the foul-smelling watery vaginal discharge.[2]
References
- ↑ 1.0 1.1 Donders GG (2007). "Definition and classification of abnormal vaginal flora". Best Pract Res Clin Obstet Gynaecol. 21 (3): 355–73. doi:10.1016/j.bpobgyn.2007.01.002. PMID 17434799.
- ↑ 2.0 2.1 GARDNER HL, DUKES CD (1955). "Haemophilus vaginalis vaginitis: a newly defined specific infection previously classified non-specific vaginitis". Am J Obstet Gynecol. 69 (5): 962–76. PMID 14361525.