Human papillomavirus physical examination: Difference between revisions

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Revision as of 19:43, 13 October 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

Physical examination

Cutaneous lesions

Warts

They are well demarcated, exophytic, hyperkeratotic papules or plaques with a rough surface that are usually located on the fingers or lateral surface of the hands that could be single or in groups.

Common wart. Adapted from Dermatology Atlas.^[1]
Common wart. Adapted from Dermatology Atlas.^[1]
Plantar wart. Adapted from Dermatology Atlas.^[1]

Epidermodysplasia verruciformis

Characterized by the growth of scaly macules and papules, that may become hypertrophic and coalescent particularly on the hands and upper trunk in children.^[2]

Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.^[1]
Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.^[1]
Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.^[1]
Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.^[1]
Epidermodysplasia verruciformis. Adapted from Dermatology Atlas.^[1]

Anogenital lesions

Intraepithelial neoplasia

Digital palpation of the vagina to assess for thickening or irregularity of the vaginal wall and a thorough colposcopic assessment of the entire vagina must be perform, however physical examination of patients with early stage is usually unremarkable, but after the insertion of a speculum and the application of acetic acid, lesions will appear as raised or flat white, granular epithelium with sharply demarcated borders and may contain areas of vascular punctation.^[3]

Condylomata acuminata

Its shape ranges from smooth flattened papule to a verrucous, papilliform appearance may be skin-colored, brown or whitish may also present as pedunculated or broad-based papillomas up to several centimeters in diameter or as large confluent plaques. Female and male genital area and perianal may be affected.^[4]

Condyloma acuminata
Condyloma acuminata
Condyloma acuminata. Adapted from Dermatology Atlas.^[1]
Condyloma acuminata. Adapted from Dermatology Atlas.^[1]
Condyloma acuminata. Adapted from Dermatology Atlas.^[1]
Condyloma acuminata. Adapted from Dermatology Atlas.^[1]
Condyloma acuminata. Adapted from Dermatology Atlas.^[1]
Condyloma acuminata. Adapted from Dermatology Atlas.^[1]
Condyloma acuminata. Adapted from Dermatology Atlas.^[1]

References

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 "Dermatology Atlas".
↑ Patel T, Morrison LK, Rady P, Tyring S (2010). "Epidermodysplasia verruciformis and susceptibility to HPV". Dis. Markers. 29 (3–4): 199–206. doi:10.3233/DMA-2010-0733. PMC 3835378. PMID 21178278.
↑ Boonlikit S, Noinual N (2010). "Vaginal intraepithelial neoplasia: a retrospective analysis of clinical features and colpohistology". J. Obstet. Gynaecol. Res. 36 (1): 94–100. doi:10.1111/j.1447-0756.2009.01108.x. PMID 20178533.
↑ Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 9781455748013.

Template:WH Template:WS

[Dermatology_Atlas-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 "Dermatology Atlas".

[pmid21178278-2] Patel T, Morrison LK, Rady P, Tyring S (2010). "Epidermodysplasia verruciformis and susceptibility to HPV". Dis. Markers. 29 (3–4): 199–206. doi:10.3233/DMA-2010-0733. PMC 3835378. PMID 21178278.

[pmid20178533-3] Boonlikit S, Noinual N (2010). "Vaginal intraepithelial neoplasia: a retrospective analysis of clinical features and colpohistology". J. Obstet. Gynaecol. Res. 36 (1): 94–100. doi:10.1111/j.1447-0756.2009.01108.x. PMID 20178533.

[mandell-4] Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 9781455748013.

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@@ Line 28: / Line 28: @@
 Digital palpation of the vagina to assess for thickening or irregularity of the vaginal wall and a thorough colposcopic assessment of the entire vagina must be perform, however physical examination of patients with early stage is usually unremarkable, but after the insertion of a speculum and the application of acetic acid, lesions will appear as raised or flat white, granular epithelium with sharply demarcated borders and may contain areas of vascular punctation.<ref name="pmid20178533">{{cite journal |vauthors=Boonlikit S, Noinual N |title=Vaginal intraepithelial neoplasia: a retrospective analysis of clinical features and colpohistology |journal=J. Obstet. Gynaecol. Res. |volume=36 |issue=1 |pages=94–100 |year=2010 |pmid=20178533 |doi=10.1111/j.1447-0756.2009.01108.x |url=}}</ref>
 ====Condylomata acuminata====
-It ranges from smooth flattened papule to a verrucous, papilliform appearance. Large lesions may be seen during physical examination. Female and male genital area and anus may be affected.<ref name=mandell>{{cite book |last = Bennett |first = John |title = Mandell, Douglas, and Bennett's principles and practice of infectious diseases |publisher = Elsevier/Saunders |location = Philadelphia, PA |year = 2015 |isbn=9781455748013}}</ref>
+Its shape ranges from smooth flattened papule to a verrucous, papilliform appearance may be skin-colored, brown or whitish may also present as pedunculated or broad-based papillomas up to several centimeters in diameter or as large confluent plaques. Female and male genital area and perianal may be affected.<ref name=mandell>{{cite book |last = Bennett |first = John |title = Mandell, Douglas, and Bennett's principles and practice of infectious diseases |publisher = Elsevier/Saunders |location = Philadelphia, PA |year = 2015 |isbn=9781455748013}}</ref>
 <gallery>
 Image:PHIL_4097_lores.jpg|Condyloma acuminata