Granulomatosis with polyangiitis epidemiology and demographics: Difference between revisions
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Males are more commonly affected with granulomatosis with polyangiitis. The overall male to female ratio is approximately 1.2 to 1. However, the ratio varies depending on geographical location.<ref name="pmid24932888">{{cite journal| author=Catanoso M, Macchioni P, Boiardi L, Manenti L, Tumiati B, Cavazza A et al.| title=Epidemiology of granulomatosis with polyangiitis (Wegener's granulomatosis) in Northern Italy: a 15-year population-based study. | journal=Semin Arthritis Rheum | year= 2014 | volume= 44 | issue= 2 | pages= 202-7 | pmid=24932888 | doi=10.1016/j.semarthrit.2014.05.005 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24932888 }} </ref> | Males are more commonly affected with granulomatosis with polyangiitis. The overall male to female ratio is approximately 1.2 to 1. However, the ratio varies depending on geographical location.<ref name="pmid24932888">{{cite journal| author=Catanoso M, Macchioni P, Boiardi L, Manenti L, Tumiati B, Cavazza A et al.| title=Epidemiology of granulomatosis with polyangiitis (Wegener's granulomatosis) in Northern Italy: a 15-year population-based study. | journal=Semin Arthritis Rheum | year= 2014 | volume= 44 | issue= 2 | pages= 202-7 | pmid=24932888 | doi=10.1016/j.semarthrit.2014.05.005 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24932888 }} </ref> | ||
In children females are more commonly seen with the disease.<ref name="pmid24891844">{{cite journal| author=Bohm M, Gonzalez Fernandez MI, Ozen S, Pistorio A, Dolezalova P, Brogan P et al.| title=Clinical features of childhood granulomatosis with polyangiitis (wegener's granulomatosis). | journal=Pediatr Rheumatol Online J | year= 2014 | volume= 12 | issue= | pages= 18 | pmid=24891844 | doi=10.1186/1546-0096-12-18 | pmc=4041043 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24891844 }} </ref> | |||
===Race=== | ===Race=== | ||
Revision as of 16:02, 31 October 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]Cafer Zorkun, M.D., Ph.D. [4]
Overview
The prevalence of Granulomatosis with polyangiitis in Europe ranges from 23.7 to 160 per million person a year, with higher prevalence rates found in northern European countries such as Norway, southern Sweden, northern Germany and the United Kingdom. The incidence of the disease is 2.4 cases per million per year, with higher incidences found in Norway, Sweden, Germany, and the United Kingdom.[1]
Epidemiology
Prevalence
The prevalence of Granulomatosis with polyangiitis in Europe ranges from 23.7 to 160 per million persons.[1]
Incidence
The incidence of Granulomatosis with polyangiitis in Europe ranges from 3 to 14.4 per million per year.[1] The incidence of Granulomatosis with polyangiitis in children ranges form 0.03 to 3.2 per 100,000 per year.[2]
Demographics
The age, sex, and race distribution of Granulomatosis with polyangiitis is dictated by the prevalence of the underlying cause within those demographic groups.
Age
The mean age of diagnosis of granulomatosis with polyangiitis is 58 years. The incidence of the disease in female patients is 70 to 79 years of age and in male patients older than 80 years.[1] The disease most commonly presents in patients that are either middle aged or elderly.[3] [4] [5] The mean age of diagnosis of Granulomatosis with polyangiitis in children is between the ages of 4 to 17. However, the disease is rarely seen in children.[2]
Gender
Males are more commonly affected with granulomatosis with polyangiitis. The overall male to female ratio is approximately 1.2 to 1. However, the ratio varies depending on geographical location.[1] In children females are more commonly seen with the disease.[6]
Race
Granulomatosis with polyangiitis usually affects individuals of the Caucasian race. Other races can be affected but have a lower prevalence rate to develop Granulomatosis with polyangiitis. [1] [7]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Catanoso M, Macchioni P, Boiardi L, Manenti L, Tumiati B, Cavazza A; et al. (2014). "Epidemiology of granulomatosis with polyangiitis (Wegener's granulomatosis) in Northern Italy: a 15-year population-based study". Semin Arthritis Rheum. 44 (2): 202–7. doi:10.1016/j.semarthrit.2014.05.005. PMID 24932888.
- ↑ 2.0 2.1 Cabral DA, Uribe AG, Benseler S, O'Neil KM, Hashkes PJ, Higgins G; et al. (2009). "Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood". Arthritis Rheum. 60 (11): 3413–24. doi:10.1002/art.24876. PMID 19877069.
- ↑ Koldingsnes W, Nossent H (2000). "Epidemiology of Wegener's granulomatosis in northern Norway". Arthritis Rheum. 43 (11): 2481–7. doi:10.1002/1529-0131(200011)43:11<2481::AID-ANR15>3.0.CO;2-6. PMID 11083271.
- ↑ Watts RA, Lane SE, Bentham G, Scott DG (2000). "Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom". Arthritis Rheum. 43 (2): 414–9. doi:10.1002/1529-0131(200002)43:2<414::AID-ANR23>3.0.CO;2-0. PMID 10693883.
- ↑ Gonzalez-Gay MA, Garcia-Porrua C, Guerrero J, Rodriguez-Ledo P, Llorca J (2003). "The epidemiology of the primary systemic vasculitides in northwest Spain: implications of the Chapel Hill Consensus Conference definitions". Arthritis Rheum. 49 (3): 388–93. doi:10.1002/art.11115. PMID 12794795.
- ↑ Bohm M, Gonzalez Fernandez MI, Ozen S, Pistorio A, Dolezalova P, Brogan P; et al. (2014). "Clinical features of childhood granulomatosis with polyangiitis (wegener's granulomatosis)". Pediatr Rheumatol Online J. 12: 18. doi:10.1186/1546-0096-12-18. PMC 4041043. PMID 24891844.
- ↑ Mohammad AJ, Jacobsson LT, Mahr AD, Sturfelt G, Segelmark M (2007). "Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden". Rheumatology (Oxford). 46 (8): 1329–37. doi:10.1093/rheumatology/kem107. PMID 17553910.