Pancreatic insufficiency

WikiDoc Resources for Pancreatic insufficiency
Articles
Most recent articles on Pancreatic insufficiency Most cited articles on Pancreatic insufficiency Review articles on Pancreatic insufficiency Articles on Pancreatic insufficiency in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Pancreatic insufficiency Images of Pancreatic insufficiency Photos of Pancreatic insufficiency Podcasts & MP3s on Pancreatic insufficiency Videos on Pancreatic insufficiency
Evidence Based Medicine
Cochrane Collaboration on Pancreatic insufficiency Bandolier on Pancreatic insufficiency TRIP on Pancreatic insufficiency
Clinical Trials
Ongoing Trials on Pancreatic insufficiency at Clinical Trials.gov Trial results on Pancreatic insufficiency Clinical Trials on Pancreatic insufficiency at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Pancreatic insufficiency NICE Guidance on Pancreatic insufficiency NHS PRODIGY Guidance FDA on Pancreatic insufficiency CDC on Pancreatic insufficiency
Books
Books on Pancreatic insufficiency
News
Pancreatic insufficiency in the news Be alerted to news on Pancreatic insufficiency News trends on Pancreatic insufficiency
Commentary
Blogs on Pancreatic insufficiency
Definitions
Definitions of Pancreatic insufficiency
Patient Resources / Community
Patient resources on Pancreatic insufficiency Discussion groups on Pancreatic insufficiency Patient Handouts on Pancreatic insufficiency Directions to Hospitals Treating Pancreatic insufficiency Risk calculators and risk factors for Pancreatic insufficiency
Healthcare Provider Resources
Symptoms of Pancreatic insufficiency Causes & Risk Factors for Pancreatic insufficiency Diagnostic studies for Pancreatic insufficiency Treatment of Pancreatic insufficiency
Continuing Medical Education (CME)
CME Programs on Pancreatic insufficiency
International
Pancreatic insufficiency en Espanol Pancreatic insufficiency en Francais
Business
Pancreatic insufficiency in the Marketplace Patents on Pancreatic insufficiency
Experimental / Informatics
List of terms related to Pancreatic insufficiency

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]

Synonyms and keywords: Exocrine pancreatic insufficiency

Overview

Pancreatic insufficiency is characterized by deficiency of the exocrine pancreatic enzymes, resulting in the inability to digest food properly, or maldigestion.

Causes

Common Causes

• Chronic alcoholism
• Chronic pancreatitis
• Cystic fibrosis
• Gall stones
• Gastrectomy
• Shwachman-Diamond syndrome
• Zollinger-Ellison syndrome

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	Diabetic gastroparesis, Hyperparathyroidism
Environmental	No underlying causes
Gastroenterologic	Chronic pancreatitis, Cystic fibrosis, Diabetic gastroparesis, Gallstones, Hemochromatosis , Short bowel syndrome
Genetic	Alpha 1-antitrypsin deficiency, Annular pancreas, Ataxia telangiectasia, Congenital lipomatosis of pancreas, Congenital pancreatic dysfunction, Congenital partial lipodystrophy, Cystic fibrosis, Havlikova syndrome, Hemochromatosis, Hereditary pancreatitis, Homocystinuria, Johanson-Blizzard syndrome, Juvenile tropical pancreatitis syndrome, Pancreatic agenesis, Pearson syndrome, Shwachman-Diamond syndrome, Situs inversus totalis with cystic dysplasia of pancreas, Wolfram's disease
Hematologic	Acute intermittent porphyria
Iatrogenic	Gastrectomy , Pancreatectomy
Infectious Disease	Mumps
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	Malnutrition
Obstetric/Gynecologic	Gestational diabetes
Oncologic	Pancreatic cancer, Zollinger-Ellison syndrome
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Autoimmune lymphoproliferative syndrome, Lupus, Polyglandular autoimmune syndrome, Sjogren's syndrome
Sexual	No underlying causes
Trauma	Trauma
Urologic	No underlying causes
Miscellaneous	Chronic alcoholism, Pancreatic cyst, Pancreatic duct obstruction, Pancreatic pseudocyst

Causes in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.

3

Diagnosis

History and Symptoms

• Fatty stools
• Muscle atrophy
• Weakness
• Weight loss

Differential Diagnosis of Causes of Pancreatic insufficiency

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.

3

Treatment

Often pancreatic insufficiency is treated with Pancreatic Enzyme Products (PEPs), such as pancrelipase, that are used to breakdown fats (lipases), proteins (proteases) and carbohydrates (amylases) into units that can be digested by those with pancreatic insufficiency.