Churg-Strauss syndrome laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, | Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). | ||
antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). Routine laboratory tests that are used to identify Eosinophila granulomatosis with polyangiitis are: | |||
'''Blood Work-up''' | |||
* Complete blood count (CBC) | |||
* Uremia | |||
* Serum creatinine | |||
* Blood urea nitrogen (BUN) | |||
* Antineutrophil cytoplasmic antibody test | |||
* Eosinophilia | |||
* Immunoglobulin | |||
* Erythrocyte sedimentation rate (ESR) | |||
* C-reactive protein (CRP) | |||
* Serum troponin<ref name="pmid23853013">{{cite journal| author=McAleavey N, Millar A, Pendleton A| title=Cardiac involvement as the main presenting feature in eosinophilic granulomatosis with polyangiitis. | journal=BMJ Case Rep | year= 2013 | volume= 2013 | issue= | pages= | pmid=23853013 | doi=10.1136/bcr-2013-009394 | pmc=3736255 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23853013 }}</ref> | |||
'''Urinalysis''' | |||
* Proteinuria | |||
* Microscopic hematuria | |||
* Red blood cell casts | |||
'''Biopsy''' | |||
Renal biopsy is the | |||
Diagnostic markers include [[eosinophil granulocyte]]s and [[granuloma]]s in affected tissue and [[Anti-neutrophil cytoplasmic antibody|Anti-neutrophil cytoplasmic antibodies (ANCA)]] against [[neutrophil granulocyte]]s. | |||
The findings on other laboratory studies is nonspecific. [[Eosinophilia]] (5K-9K/uL) may be present. [[Anemia]], elevated [[erythrocyte sedimentation rate]] ([[ESR]]), [[leukocytosis]], elevated [[immunoglobin E]] ([[IgE]]), [[hypergammaglobulinemia]], and a low-positive [[rheumatoid factor]] ([[RF]] | |||
Revision as of 15:28, 14 November 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE).
Laboratory Findings
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). Routine laboratory tests that are used to identify Eosinophila granulomatosis with polyangiitis are:
Blood Work-up
- Complete blood count (CBC)
- Uremia
- Serum creatinine
- Blood urea nitrogen (BUN)
- Antineutrophil cytoplasmic antibody test
- Eosinophilia
- Immunoglobulin
- Erythrocyte sedimentation rate (ESR)
- C-reactive protein (CRP)
- Serum troponin[1]
Urinalysis
- Proteinuria
- Microscopic hematuria
- Red blood cell casts
Biopsy
Renal biopsy is the
Diagnostic markers include eosinophil granulocytes and granulomas in affected tissue and Anti-neutrophil cytoplasmic antibodies (ANCA) against neutrophil granulocytes.
The findings on other laboratory studies is nonspecific. Eosinophilia (5K-9K/uL) may be present. Anemia, elevated erythrocyte sedimentation rate (ESR), leukocytosis, elevated immunoglobin E (IgE), hypergammaglobulinemia, and a low-positive rheumatoid factor (RF
References
- ↑ McAleavey N, Millar A, Pendleton A (2013). "Cardiac involvement as the main presenting feature in eosinophilic granulomatosis with polyangiitis". BMJ Case Rep. 2013 ( ): . doi:10.1136/bcr-2013-009394. PMC 3736255. PMID 23853013.