Differentiating Churg-Strauss syndrome from other diseases: Difference between revisions
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{{Churg-Strauss syndrome}} | {{Churg-Strauss syndrome}} | ||
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==Overview== | ==Overview== | ||
Eosinophilic granulomatosis with polyangiits must be differentiated from other diseases that can cause purpura, alveolar hemorrhage, fever, arthralgia, myalgia, necrotizing extra-capillary glomerulonephritis, such as Granulomatosis with polyangiitis and Microscopic polyangiitis.<ref name="pmid27733943">{{cite journal| author=Pagnoux C| title=Updates in ANCA-associated vasculitis. | journal=Eur J Rheumatol | year= 2016 | volume= 3 | issue= 3 | pages= 122-133 | pmid=27733943 | doi=10.5152/eurjrheum.2015.0043 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27733943 }} </ref> | Eosinophilic granulomatosis with polyangiits must be differentiated from other diseases that can cause purpura, alveolar hemorrhage, fever, arthralgia, myalgia, necrotizing extra-capillary glomerulonephritis, such as Granulomatosis with polyangiitis and Microscopic polyangiitis.<ref name="pmid27733943">{{cite journal| author=Pagnoux C| title=Updates in ANCA-associated vasculitis. | journal=Eur J Rheumatol | year= 2016 | volume= 3 | issue= 3 | pages= 122-133 | pmid=27733943 | doi=10.5152/eurjrheum.2015.0043 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27733943 }} </ref> | ||
==Differentiating | ==Differentiating Eosinophilic granulomatosis with polyangiitis from other Diseases== | ||
* Differentiation of Churg-Strauss syndrome from [[Wegener's granulomatosis]] can be difficult, though the increasing use of [[ANCA]] assays has made the distinction more routine. Wegener's is closely associated with [[c-ANCA]], unlike Churg-Strauss which shows elevations of [[p-ANCA]]. | * Differentiation of Churg-Strauss syndrome from [[Wegener's granulomatosis]] can be difficult, though the increasing use of [[ANCA]] assays has made the distinction more routine. Wegener's is closely associated with [[c-ANCA]], unlike Churg-Strauss which shows elevations of [[p-ANCA]]. | ||
* Churg-Strauss syndrome was once considered a type of [[polyarteritis nodosa|Polyarteritis nodosa (PAN)]] due to their similar morphologies. | * Churg-Strauss syndrome was once considered a type of [[polyarteritis nodosa|Polyarteritis nodosa (PAN)]] due to their similar morphologies. | ||
Revision as of 14:00, 21 November 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
Eosinophilic granulomatosis with polyangiits must be differentiated from other diseases that can cause purpura, alveolar hemorrhage, fever, arthralgia, myalgia, necrotizing extra-capillary glomerulonephritis, such as Granulomatosis with polyangiitis and Microscopic polyangiitis.[1]
Differentiating Eosinophilic granulomatosis with polyangiitis from other Diseases
- Differentiation of Churg-Strauss syndrome from Wegener's granulomatosis can be difficult, though the increasing use of ANCA assays has made the distinction more routine. Wegener's is closely associated with c-ANCA, unlike Churg-Strauss which shows elevations of p-ANCA.
- Churg-Strauss syndrome was once considered a type of Polyarteritis nodosa (PAN) due to their similar morphologies.
References
- ↑ Pagnoux C (2016). "Updates in ANCA-associated vasculitis". Eur J Rheumatol. 3 (3): 122–133. doi:10.5152/eurjrheum.2015.0043. PMID 27733943.