Churg-Strauss syndrome laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). Routine laboratory tests that are used to identify Eosinophilic granulomatosis with polyangiitis are: | Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). Routine laboratory tests that are used to identify Eosinophilic granulomatosis with polyangiitis are:<ref name="pmid14819261">{{cite journal| author=CHURG J, STRAUSS L| title=Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. | journal=Am J Pathol | year= 1951 | volume= 27 | issue= 2 | pages= 277-301 | pmid=14819261 | doi= | pmc=1937314 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14819261 }}</ref> <ref name="pmid24530234">{{cite journal| author=Mouthon L, Dunogue B, Guillevin L| title=Diagnosis and classification of eosinophilic granulomatosis with polyangiitis (formerly named Churg-Strauss syndrome). | journal=J Autoimmun | year= 2014 | volume= 48-49 | issue= | pages= 99-103 | pmid=24530234 | doi=10.1016/j.jaut.2014.01.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24530234 }}</ref> | ||
'''Blood Work-up''' | '''Blood Work-up''' | ||
Revision as of 16:30, 21 November 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE).
Laboratory Findings
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). Routine laboratory tests that are used to identify Eosinophilic granulomatosis with polyangiitis are:[1] [2]
Blood Work-up
- Complete blood count (CBC)
- Uremia
- Serum creatinine
- Blood urea nitrogen (BUN)
- Antineutrophil cytoplasmic antibody test
- Eosinophilia
- Immunoglobulin
- Erythrocyte sedimentation rate (ESR)
- C-reactive protein (CRP)
- Serum troponin[3]
- Rheumatoid factor
Urinalysis
- Proteinuria
- Microscopic hematuria
- Albuminuria
- Red blood cell casts
Biopsy
The gold standard in establishing a diagnosis for Eosinophilic granulomatosis with polyangiitis is a lung biopsy.[4]
References
- ↑ CHURG J, STRAUSS L (1951). "Allergic granulomatosis, allergic angiitis, and periarteritis nodosa". Am J Pathol. 27 (2): 277–301. PMC 1937314. PMID 14819261.
- ↑ Mouthon L, Dunogue B, Guillevin L (2014). "Diagnosis and classification of eosinophilic granulomatosis with polyangiitis (formerly named Churg-Strauss syndrome)". J Autoimmun. 48-49 ( ): 99–103. doi:10.1016/j.jaut.2014.01.018. PMID 24530234.
- ↑ McAleavey N, Millar A, Pendleton A (2013). "Cardiac involvement as the main presenting feature in eosinophilic granulomatosis with polyangiitis". BMJ Case Rep. 2013 ( ): . doi:10.1136/bcr-2013-009394. PMC 3736255. PMID 23853013.
- ↑ Allen JN, Davis WB (1994). "Eosinophilic lung diseases". Am J Respir Crit Care Med. 150 (5 Pt 1): 1423–38. doi:10.1164/ajrccm.150.5.7952571. PMID 7952571.