Interstitial nephritis causes: Difference between revisions

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==Causes==
==Causes==
Common causes include infection, or reaction to medication (such as an [[analgesic]] or [[antibiotic]]s). 71%<ref name="pmid14671029">{{cite journal |author=Baker R, Pusey C |title=The changing profile of acute tubulointerstitial nephritis |journal=Nephrol Dial Transplant |volume=19 |issue=1 |pages=8-11 |year=2004 |pmid=14671029|url=http://ndt.oxfordjournals.org/cgi/content/full/19/1/8}}</ref> to 92%<ref name="pmid15340098">{{cite journal |author=Clarkson M, Giblin L, O'Connell F, O'Kelly P, Walshe J, Conlon P, O'Meara Y, Dormon A, Campbell E, Donohoe J |title=Acute interstitial nephritis: clinical features and response to corticosteroid therapy |journal=Nephrol Dial Transplant |volume=19 |issue=11 |pages=2778-83 |year=2004 |pmid=15340098}}</ref> of cases are reported to be caused by drugs. This disease is also caused by other diseases and toxins that do damage to the kidney.  Both acute and chronic tubulointerstitial nephritis can be caused by a bacterial infection in the kidneys, known as [[pyelonephritis]]. The most common cause is by an allergic reaction to a drug.  The drugs that are known to cause this sort of reaction are antibiotics such as penicillin, and nonsteroidal anti-inflammatory drugs, such as aspirin.  The time between exposure to the drug and the development of acute tubulointerstitial nephritis can be anywhere from 5 days to 5 weeks.
Common causes include infection, or reaction to medication (such as an [[analgesic]] or [[antibiotic]]s). 71%<ref name="pmid14671029">{{cite journal |author=Baker R, Pusey C |title=The changing profile of acute tubulointerstitial nephritis |journal=Nephrol Dial Transplant |volume=19 |issue=1 |pages=8-11 |year=2004 |pmid=14671029|url=http://ndt.oxfordjournals.org/cgi/content/full/19/1/8}}</ref> to 92%<ref name="pmid15340098">{{cite journal |author=Clarkson M, Giblin L, O'Connell F, O'Kelly P, Walshe J, Conlon P, O'Meara Y, Dormon A, Campbell E, Donohoe J |title=Acute interstitial nephritis: clinical features and response to corticosteroid therapy |journal=Nephrol Dial Transplant |volume=19 |issue=11 |pages=2778-83 |year=2004 |pmid=15340098}}</ref> of cases are reported to be caused by drugs. This disease is also caused by other diseases and toxins that do damage to the kidney.  Both acute and chronic tubulointerstitial nephritis can be caused by a bacterial infection in the kidneys, known as [[pyelonephritis]]. The most common cause is by an allergic reaction to a drug.  The drugs that are known to cause this sort of reaction are antibiotics such as penicillin, and nonsteroidal anti-inflammatory drugs, such as aspirin.  The time between exposure to the drug and the development of acute tubulointerstitial nephritis can be anywhere from 5 days to 5 weeks.
===Causes by Organ System===
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Granulomatosis with polyangiitis]],  [[Kawasaki's disease]]
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
|bgcolor="Beige"| [[Aristolochia]],  [[Quinine]],  [[Thiazide diuretics]]
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| [[Rubeola infection]],
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Acetaminophen ]],  [[Acyclovir]],  [[Aldomet]],  [[Allopurinol]],  [[Alpha-interferon]],  [[Amlodipine]],  [[Ampicillin]],  [[Anitrim]],  [[Anti-tubular basement membrane antibodies ]],  [[Apo-sulfatrim]],  [[Aspirin]],  [[Azathioprine]],  [[Bactelan]],  [[Batrizol]],  [[Bumetanide]],  [[Captopril]],  [[Carbamazepine]],  [[Cefaclor]],  [[Cefotaxime sodium]],  [[Cefoxitin sodium]],  [[Cephalosporin]],  [[Chlorthalidone]],  [[Cimetidine ]],  [[Ciprofloxacin]],  [[Clofibrate]],  [[Cox-2 inhibitors]],  [[Creatine]],  [[Dabrafenib mesylate]],  [[Diazepam]],  [[Diclofenac]],  [[Diflunisal]],  [[Diltiazem]],  [[Diphenylhydantoin]],  [[Diuretics]],  [[Doxycycline]],  [[Ectaprim]],  [[Enterobacticel]],  [[Erythromycin]],  [[Esteprim]],  [[Ethambutol]],  [[Famotidine]],  [[Fenoprofen]],  [[Flurbiprofen]],  [[Furosemide]],  [[Griseofulvin]],  [[Hydralazine]],  [[Hydrochlorothiazide]],  [[Ibuprofen]],  [[Indinavir]],  [[Indomethacin]],  [[Isobac]],  [[Isoniazid]],  [[Kelfiprim]],  [[Ketoprofen]],  [[Lansoprazole]],  [[Macrolides]],  [[Mesalamine]],  [[Mesalazine]],  [[Methicillin]],  [[Metoxiprim]],  [[Minocycline hydrochloride]],  [[Naproxen]],  [[Novo-trimel]],  [[Nu-cotrimox]],  [[Olsalazine]],  [[Omeprazole]],  [[Oxacillin]],  [[Oxaprozin]],  [[Oxytetracycline]],  [[Pegylated interferon alfa-2b]],  [[Penicillin ]],  [[Phenindione]],  [[Phenobarbital]],  [[Phenteramine]],  [[Phenylpropanolamine]],  [[Phenytoin]],  [[Piperacillin/tazobactam]],  [[Piroxicam]],  [[Polymyxin]],  [[Pranlukast]],  [[Propylthioruacil]],  [[Pro-trin]],  [[Rabeprazole]],  [[Ranitidine]],  [[Rifampin]],  [[Roubac]],  [[Streptomycin]],  [[Sulfatrim ds]],  [[Sulfinpyrazone]],  [[Sulfonamide]],  [[Sulfoxaprim]],  [[Sulindac]],  [[Syraprim]],  [[Tenofovir disoproxil fumarate]],  [[Tetracycline]],  [[Thiazide diuretics]],  [[Tolmetin]],  [[Treponema]],  [[Triamterene]],  [[Trimesuxol]],  [[Trimethoprim-sulfamethoxazole]],  [[Trimetoger]],  [[Trimetox]],  [[Trimzol]],  [[Trisulfa]],  [[Trisulfam]],  [[Uroplus ds]],  [[Uroplus ss]],  [[Vancomycin]]
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| [[Sjogren syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| [[Escherichia coli]],  [[Inflammatory bowel disease]]
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| [[Alport syndrome]],  [[Bardet-biedl syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| [[Hypercalcemia]],  [[Hyperkalaemic distal renal tubular acidosis]],  [[Hyperuricemia]],  [[Hypokalemia]],  [[Sickle cell disease]]
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| [[Adenovirus]],  [[Brucella]],  [[Candida]],  [[Chlamydia]],  [[Coccidioidomycosis]],  [[Corynebacterium diphtheriae]],  [[Cytomegalovirus]],  [[Diphtheria]],  [[Enterococcus]],  [[Epstein-barr virus ]],  [[Escherichia coli]],  [[Francisella]],  [[Hantaan virus]],  [[Histoplasmosis]],  [[Hiv infection]],  [[Legionellosis]],  [[Leishmaniasis]],  [[Leptospirosis]],  [[Mycobacterium tuberculosis]],  [[Mycoplasma infection]],  [[Polyomavirus]],  [[Rickettsia infection]],  [[Rubeola infection]],  [[Streptococcal infection]],  [[Syphilis]],  [[Toxoplasmosis]],  [[Uveitis]],  [[Yersinia]]
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| [[Creatine]],  [[Hyperuricemia]],  [[Hypokalemia]]
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| [[Myeloma]]
|-
|-bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
|bgcolor="Beige"| [[Uveitis]]
|-
|-bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
|bgcolor="Beige"| [[Cocaine]]
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| [[Hantaan virus]],  [[Histoplasmosis]],  [[Sarcoidosis]]
|-
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
|bgcolor="Beige"| [[Alport syndrome]],  [[Granulomatosis with polyangiitis]],  [[Hyperkalaemic distal renal tubular acidosis]],  [[Reflux nephropathy]],  [[Renal failure]],  [[Sensenbrenner syndrome]],  [[Tubulointerstitial nephritis]],  [[Wegener's granulomatosis]]
|-
|-bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| [[Igg4-related disease]],  [[Kawasaki's disease]],  [[Sarcoidosis]],  [[Sicca syndrome]],  [[Systemic lupus erythematosus]]
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| [[Hiv infection]],  [[Syphilis]]
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|-
|}
===Causes in Alphabetical Order===
===Causes in Alphabetical Order===
{{columns-list|3|
{{columns-list|3|

Revision as of 21:59, 23 November 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

Common causes include infection, or reaction to medication (such as an analgesic or antibiotics). 71%[1] to 92%[2] of cases are reported to be caused by drugs. This disease is also caused by other diseases and toxins that do damage to the kidney. Both acute and chronic tubulointerstitial nephritis can be caused by a bacterial infection in the kidneys, known as pyelonephritis. The most common cause is by an allergic reaction to a drug. The drugs that are known to cause this sort of reaction are antibiotics such as penicillin, and nonsteroidal anti-inflammatory drugs, such as aspirin. The time between exposure to the drug and the development of acute tubulointerstitial nephritis can be anywhere from 5 days to 5 weeks.

Causes by Organ System

Cardiovascular Granulomatosis with polyangiitis, Kawasaki's disease
Chemical/Poisoning Aristolochia, Quinine, Thiazide diuretics
Dental No underlying causes
Dermatologic Rubeola infection,
Drug Side Effect Acetaminophen , Acyclovir, Aldomet, Allopurinol, Alpha-interferon, Amlodipine, Ampicillin, Anitrim, Anti-tubular basement membrane antibodies , Apo-sulfatrim, Aspirin, Azathioprine, Bactelan, Batrizol, Bumetanide, Captopril, Carbamazepine, Cefaclor, Cefotaxime sodium, Cefoxitin sodium, Cephalosporin, Chlorthalidone, Cimetidine , Ciprofloxacin, Clofibrate, Cox-2 inhibitors, Creatine, Dabrafenib mesylate, Diazepam, Diclofenac, Diflunisal, Diltiazem, Diphenylhydantoin, Diuretics, Doxycycline, Ectaprim, Enterobacticel, Erythromycin, Esteprim, Ethambutol, Famotidine, Fenoprofen, Flurbiprofen, Furosemide, Griseofulvin, Hydralazine, Hydrochlorothiazide, Ibuprofen, Indinavir, Indomethacin, Isobac, Isoniazid, Kelfiprim, Ketoprofen, Lansoprazole, Macrolides, Mesalamine, Mesalazine, Methicillin, Metoxiprim, Minocycline hydrochloride, Naproxen, Novo-trimel, Nu-cotrimox, Olsalazine, Omeprazole, Oxacillin, Oxaprozin, Oxytetracycline, Pegylated interferon alfa-2b, Penicillin , Phenindione, Phenobarbital, Phenteramine, Phenylpropanolamine, Phenytoin, Piperacillin/tazobactam, Piroxicam, Polymyxin, Pranlukast, Propylthioruacil, Pro-trin, Rabeprazole, Ranitidine, Rifampin, Roubac, Streptomycin, Sulfatrim ds, Sulfinpyrazone, Sulfonamide, Sulfoxaprim, Sulindac, Syraprim, Tenofovir disoproxil fumarate, Tetracycline, Thiazide diuretics, Tolmetin, Treponema, Triamterene, Trimesuxol, Trimethoprim-sulfamethoxazole, Trimetoger, Trimetox, Trimzol, Trisulfa, Trisulfam, Uroplus ds, Uroplus ss, Vancomycin
Ear Nose Throat Sjogren syndrome
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic Escherichia coli, Inflammatory bowel disease
Genetic Alport syndrome, Bardet-biedl syndrome
Hematologic Hypercalcemia, Hyperkalaemic distal renal tubular acidosis, Hyperuricemia, Hypokalemia, Sickle cell disease
Iatrogenic No underlying causes
Infectious Disease Adenovirus, Brucella, Candida, Chlamydia, Coccidioidomycosis, Corynebacterium diphtheriae, Cytomegalovirus, Diphtheria, Enterococcus, Epstein-barr virus , Escherichia coli, Francisella, Hantaan virus, Histoplasmosis, Hiv infection, Legionellosis, Leishmaniasis, Leptospirosis, Mycobacterium tuberculosis, Mycoplasma infection, Polyomavirus, Rickettsia infection, Rubeola infection, Streptococcal infection, Syphilis, Toxoplasmosis, Uveitis, Yersinia
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic Creatine, Hyperuricemia, Hypokalemia
Obstetric/Gynecologic No underlying causes
Oncologic Myeloma
Ophthalmologic Uveitis
Overdose/Toxicity Cocaine
Psychiatric No underlying causes
Pulmonary Hantaan virus, Histoplasmosis, Sarcoidosis
Renal/Electrolyte Alport syndrome, Granulomatosis with polyangiitis, Hyperkalaemic distal renal tubular acidosis, Reflux nephropathy, Renal failure, Sensenbrenner syndrome, Tubulointerstitial nephritis, Wegener's granulomatosis
Rheumatology/Immunology/Allergy Igg4-related disease, Kawasaki's disease, Sarcoidosis, Sicca syndrome, Systemic lupus erythematosus
Sexual Hiv infection, Syphilis
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3

References

  1. ↑ Baker R, Pusey C (2004). "The changing profile of acute tubulointerstitial nephritis". Nephrol Dial Transplant. 19 (1): 8–11. PMID 14671029.
  2. ↑ Clarkson M, Giblin L, O'Connell F, O'Kelly P, Walshe J, Conlon P, O'Meara Y, Dormon A, Campbell E, Donohoe J (2004). "Acute interstitial nephritis: clinical features and response to corticosteroid therapy". Nephrol Dial Transplant. 19 (11): 2778–83. PMID 15340098.

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