Von Willebrand disease epidemiology and demographics: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Prevalence=== | |||
The prevalence of von Willebrand’s disease is 0.6 to 1.3%.<ref name="pmid18315614">{{cite journal| author=Nichols WL, Hultin MB, James AH, Manco-Johnson MJ, Montgomery RR, Ortel TL et al.| title=von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA). | journal=Haemophilia | year= 2008 | volume= 14 | issue= 2 | pages= 171-232 | pmid=18315614 | doi=10.1111/j.1365-2516.2007.01643.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18315614 }} </ref><ref name="pmid3492222">{{cite journal| author=Rodeghiero F, Castaman G, Dini E| title=Epidemiological investigation of the prevalence of von Willebrand's disease. | journal=Blood | year= 1987 | volume= 69 | issue= 2 | pages= 454-9 | pmid=3492222 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3492222 }} </ref> | |||
It is estimated that the referral prevalence of von Willebrand’s disease is approximately 1 case per 10,000 persons. | |||
The actual abnormality (which does not necessarily lead to disease) occurs in 0.9-3% of the population. | |||
===Age=== | |||
===Gender=== | |||
Although autosomal inheritance pattern of disease lead to an equal distribution of male patients and female patients, the disease has female predominance whose bleeding tendency shows during [[menstruation]]. | |||
===Race=== | |||
There is no racial predilection to [[vWD]] however, it may be more severe or apparent in people with [[blood type]] O. | |||
==References== | ==References== | ||
Revision as of 16:56, 28 November 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Epidemiology and Demographics
Prevalence
The prevalence of von Willebrand’s disease is 0.6 to 1.3%.[1][2] It is estimated that the referral prevalence of von Willebrand’s disease is approximately 1 case per 10,000 persons.
The actual abnormality (which does not necessarily lead to disease) occurs in 0.9-3% of the population.
Age
Gender
Although autosomal inheritance pattern of disease lead to an equal distribution of male patients and female patients, the disease has female predominance whose bleeding tendency shows during menstruation.
Race
There is no racial predilection to vWD however, it may be more severe or apparent in people with blood type O.
References
- ↑ Nichols WL, Hultin MB, James AH, Manco-Johnson MJ, Montgomery RR, Ortel TL; et al. (2008). "von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA)". Haemophilia. 14 (2): 171–232. doi:10.1111/j.1365-2516.2007.01643.x. PMID 18315614.
- ↑ Rodeghiero F, Castaman G, Dini E (1987). "Epidemiological investigation of the prevalence of von Willebrand's disease". Blood. 69 (2): 454–9. PMID 3492222.