Primary sclerosing cholangitis pathophysiology: Difference between revisions
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===Genetics=== | ===Genetics=== | ||
===Associated Conditions=== | ===Associated Conditions=== | ||
*[[Inflammatory bowel disease]] ([[IBD]]): approximately 70-80% of patients with primary sclerosing cholangitis have [[IBD]] ([[Crohn's disease]] and [[ulcerative colitis]]).<ref name="pmid21351115">{{cite journal |vauthors=Molodecky NA, Kareemi H, Parab R, Barkema HW, Quan H, Myers RP, Kaplan GG |title=Incidence of primary sclerosing cholangitis: a systematic review and meta-analysis |journal=Hepatology |volume=53 |issue=5 |pages=1590–9 |year=2011 |pmid=21351115 |doi=10.1002/hep.24247 |url=}}</ref> | |||
*[[Autoimmune hepatitis]]: approximately 35% of children with primary sclerosing cholangitis have associated [[autoimmune hepatitis]], while only 5% of adults have combined primary sclerosing cholangitis with associated [[autoimmune hepatitis]]. | |||
*[[Gallbladder]] disease: this includes [[gallbladder stones]], [[polyps]] and cancer. | |||
==References== | ==References== | ||
Revision as of 23:28, 8 December 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Pathophysiology
Gross Pathology
Microscopic Pathology
Genetics
Associated Conditions
- Inflammatory bowel disease (IBD): approximately 70-80% of patients with primary sclerosing cholangitis have IBD (Crohn's disease and ulcerative colitis).[1]
- Autoimmune hepatitis: approximately 35% of children with primary sclerosing cholangitis have associated autoimmune hepatitis, while only 5% of adults have combined primary sclerosing cholangitis with associated autoimmune hepatitis.
- Gallbladder disease: this includes gallbladder stones, polyps and cancer.
References
- ↑ Molodecky NA, Kareemi H, Parab R, Barkema HW, Quan H, Myers RP, Kaplan GG (2011). "Incidence of primary sclerosing cholangitis: a systematic review and meta-analysis". Hepatology. 53 (5): 1590–9. doi:10.1002/hep.24247. PMID 21351115.