Hyperthermia causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Life threatning causes of hyperthermia include diabetic ketoacidosis, heat stroke, malignant hyperthermia, and septic shock. Other common causes of hyperthermia are amphetamine, cocaine, monoamine oxidase inhibitors and selective serotonin reuptake inhibitors.

Causes

Life Threatening Causes

• Diabetic ketoacidosis
• Heat stroke
• Malignant hyperthermia
• Neonatal sepsis
• Septic shock

Common Causes

• Amphetamine
• Cocaine
• Monoamine oxidase inhibitors
• Selective serotonin reuptake inhibitors
• Tricyclic antidepressants

Causes by Organ System

Cardiovascular	Dressler syndrome,Kawasaki disease
Chemical/Poisoning	Methyl bromide, saponin, acetylsalicylic acid, amphetamine poisoning, anticholinergic poisoning, antipsychotic poisoning, benzphetamine hydrochloride, boric acid, cathinone poisoning, cobra poisoning, cocaine poisoning, cyclic antidepressant poisoning, dinitrocresol, dinitrophenol, funnel web spider poisoning, hexachlorobenzene, lysergic acid diethylamide, MAO inhibitor poisoning, metaldehyde, mustard tree poisoning, nitrogen dioxide, phencyclidine poisoning, salicylate poisoning, strychnine, toxaphene, toxic mushrooms
Dental	No underlying causes
Dermatologic	Cellulitis, hidradenitis suppurativa, hydroa vacciniforme, impetigo herpetiformis, scarlet fever, thrombotic thrombocytopenic purpura,
Drug Side Effect	5-azacytidine, abacavir, amphetamines, anticholinergics, asparaginase, benztropine mesylate, bleomycin, bretylium tosylate, cocaine, cyclic antidepressant poisoning, dabrafenib, didrex, dimercaprol, dinoprostone, diphtheria-pertussis-tetanus vaccine, elotuzumab, elspar, eribulin mesylate, ganciclovir, glycopyrrolate, imatinib mesylate, ioxilan, Leunase,LSD, MDMA, methscopolamine bromide, mepenzolate, micafungin, MMR vaccine, monoamine oxidase inhibitors, muscarinic antagonists, oxaliplatin, para-amino salicylic acid, PCP, penicillaminepropantheline bromide, psychostimulant drugs, psychotropic medications, pyrazinamide, selective serotonin reuptake inhibitors, Serotonin syndrome, succimer, Talimogene laherparepvec, tricyclic antidepressants, valganciclovir
Ear Nose Throat	Vincent angina
Endocrine	De Quervain's thyroiditis ,diabetic ketoacidosis,pheochromocytoma,thyroid storm
Environmental	Humidity
Gastroenterologic	Cholecystitis,gallbladder empyema,yellow fever
Genetic	Crisponi syndrome,pseudodiastrophic dysplasia,Stuve-Wiedemann dysplasia
Hematologic	Acute infantile hemorrhagic oedema, blood transfusion and complications, Burkitt lymphoma, lymphangitis, lymphoma, thrombotic thrombocytopenic purpura, tropical pulmonary eosinophilia
Iatrogenic	No underlying causes
Infectious Disease	Acute disseminated encephalomyelitis, anthrax, babesiosis, bartonellosis, Bornholm disease, brain abscess, Brazilian purpuric fever, campylobacter jejuni, caspofungin, cellulitis, Chagas disease, Colorado tick fever, common cold, cystitis, infective, dengue, ehrlichia ewingii, encephalitis, epiglottitis, erysipelas,erysipeloid of rosenbach, gallbladder empyema, hand-foot-mouth syndrome, heartland virus, herpes virus 6, human monocytotropic ehrlichiosis, influenza, Kunjin virus, lassa fever, lymphangitis, malaria, measles, mediastinitis, meningitis, Murray Valley encephalitis virus, Nanukayami, Oklahoma tick fever, neonatal sepsis, orbital cellulitis, PCP, pelvic inflammatory disease, pericoronitis, rabies, rickettsia prowazekii, scarlet fever, schistosoma haematobium, secondary syphilis, Sennetsu fever, sepsis, septic shock, smallpox, staphylococcal toxic shock syndrome, subacute sclerosing leukoencephalitis, tanapox virus disease, tetanus, toxic shock syndrome, trench fever, trichinella spiralis, tropical pulmonary eosinophilia, typhoid fever, vincent angina, viral haemorrhagic fever, yellow fever, yersinia pestisZika virus disease,
Musculoskeletal/Orthopedic	Malignant hyperpyrexia
Neurologic	Acute disseminated encephalomyelitis, Aicardi-Goutieres syndrome, autonomic neuropathy, brain abscess, cerebral hemorrhage, familial hemiplegic migraine, meningitis, status epilepticus, subacute sclerosing leukoencephalitis
Nutritional/Metabolic	Calcitriol, dehydration, Gtp cyclohydrolase deficiency, heat cramps, hypernatremia, hyponatremia, Ornithine transcarbamylase deficiency, streptokinase
Obstetric/Gynecologic	Pelvic inflammatory disease, puerperal pyrexia
Oncologic	Burkitt lymphoma, leukemia, lymphoma, mastocytosis, nephroblastoma
Ophthalmologic	Orbital cellulitis
Overdose/Toxicity	Autumn crocus, Cocaine overdose, Ecstasy abuse, MDMA
Psychiatric	Neuroleptic malignant syndrome
Pulmonary	Bronchiolitis obliterans organizing pneumonia, common cold, extrinsic allergic alveolitis, Idiopathic pulmonary haemosiderosis, lymphocytic interstitial pneumonia, mediastinitis, PCP, severe acute respiratory syndrome,
Renal/Electrolyte	Nephroblastoma, renal infarction
Rheumatology/Immunology/Allergy	Acute disseminated encephalomyelitis, Aicardi-Goutieres syndrome, Interferon beta, Interferon gamma, Interleukin 2, Kawasaki disease, macrophage activation syndrome, thrombotic thrombocytopenic purpura, urate crystal arthropathy
Sexual	No underlying causes
Trauma	Crush injury
Urologic	Cystitis infective, malakoplakia
Miscellaneous	Pyrexia of unknown origin

Causes in Alphabetical Order

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