Von Willebrand disease screening: Difference between revisions
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==Screening== | ==Screening== | ||
{| class="wikitable" | |||
!Symptom/score | |||
!-1 | |||
!0 | |||
!1 | |||
!2 | |||
!3 | |||
!4 | |||
|- | |||
!'''Epistaxis''' | |||
|'''-''' | |||
|No or trivial (≤5 per | |||
year) | |||
|>5 per year OR >10 | |||
minutes duration | |||
|Consultation only | |||
|Packing, cauterization or | |||
antifibrinolytics | |||
|Blood transfusion, replacement | |||
therapy or desmopressin | |||
|- | |||
!'''Cutaneous''' | |||
|'''-''' | |||
|No or trivial (≤1cm) | |||
|>1cm AND no trauma | |||
|Consultation only | |||
| - | |||
| - | |||
|- | |||
!'''Minor wounds''' | |||
|'''-''' | |||
|No or trivial (≤5 per | |||
year) | |||
|>5 per year OR >5 | |||
minutes duration | |||
|Consultation only or Steristrips | |||
|Surgical hemostasis or | |||
antifibrinolytics | |||
|Blood transfusion, replacement | |||
therapy or desmopressin | |||
|- | |||
!'''Oral cavity''' | |||
|'''-''' | |||
|No | |||
|Reported at least once | |||
|Consultation only | |||
|Surgical hemostasis or | |||
antifibrinolytics | |||
|Blood transfusion, replacement | |||
therapy or desmopressin | |||
|- | |||
!'''Gastrointestinal''' | |||
'''tract''' | |||
|'''-''' | |||
|No | |||
|Identified cause | |||
|Consultation or spontaneous | |||
|Surgical hemostasis, | |||
antifibrinolytics, blood | |||
transfusion, replacement therapy | |||
or desmopressin | |||
| - | |||
|- | |||
!'''Tooth extraction''' | |||
|No bleeding in at least | |||
2 extractions | |||
|None done or no | |||
bleeding in 1 | |||
extraction | |||
|Reported, no | |||
consultation | |||
|Consultation only | |||
|Resuturing, repacking or | |||
antifibrinolytic | |||
|Blood transfusion, replacement | |||
therapy or desmopressin | |||
|- | |||
!'''Surgery''' | |||
|No bleeding in at least | |||
2 surgeries | |||
|None done or no | |||
bleeding in 1 | |||
|Reported, no | |||
consultation | |||
|Consultation only | |||
|Surgical hemostasis or | |||
antifibrinolytics | |||
|Blood transfusion, replacement | |||
therapy or desmopressin | |||
|- | |||
!'''Menorrhagia''' | |||
| - | |||
|No | |||
|Reported or consultation | |||
only | |||
|Antifibrinolytics or | |||
contraceptive pill use | |||
|D&C or iron therapy | |||
|Blood transfusion, replacement | |||
therapy or desmopressin | |||
|- | |||
!'''Post-partum''' | |||
|No bleeding in at least | |||
2 deliveries | |||
|No deliveries or no | |||
bleeding in 1 delivery | |||
|Reported or consultation | |||
only | |||
|D&C, iron therapy or | |||
antifibrinolytics | |||
|Blood transfusion, replacement | |||
therapy or desmopressin | |||
| - | |||
|- | |||
!'''Muscle hematoma''' | |||
| - | |||
|Never | |||
|Post-trauma, no therapy | |||
|Spontaneous, no therapy | |||
|Spontaneous or traumatic, | |||
requiring replacement therapy or | |||
desmopressin | |||
|Spontaneous or traumatic, | |||
requiring surgical intervention | |||
or blood transfusion | |||
|- | |||
|'''Hemarthrosis''' | |||
| '''-''' | |||
|'''Never''' | |||
|Post-trauma, no therapy | |||
|Spontaneous, no therapy | |||
|Spontaneous or traumatic, | |||
requiring replacement therapy or | |||
desmopressin | |||
|Spontaneous or traumatic, | |||
requiring surgical intervention | |||
or blood transfusion | |||
|- | |||
|'''Central nervous''' | |||
'''system''' | |||
| '''-''' | |||
|'''Never''' | |||
| - | |||
| - | |||
|Subdural, any intervention | |||
|Intracerebral, any intervention | |||
|- | |||
|'''Other *''' | |||
| '''-''' | |||
|'''No''' | |||
|Reported | |||
|Consultation only | |||
|Surgical hemostasis, | |||
antifibrinolytics or iron therapy | |||
|Blood transfusion, replacement | |||
therapy or desmopressin | |||
|} | |||
Scoring key for the Pediatric Bleeding Questionnaire. In the last row, the symptoms included in the "Other" category are umbilical stump bleeding, cephalhematoma, post-circumcision bleeding, post-venipuncture bleeding, and macroscopic hematuria | Scoring key for the Pediatric Bleeding Questionnaire. In the last row, the symptoms included in the "Other" category are umbilical stump bleeding, cephalhematoma, post-circumcision bleeding, post-venipuncture bleeding, and macroscopic hematuria | ||
Revision as of 14:40, 15 December 2016
Von Willebrand disease Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Von Willebrand disease screening On the Web |
American Roentgen Ray Society Images of Von Willebrand disease screening |
Risk calculators and risk factors for Von Willebrand disease screening |
Von Willebrand disease Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Von Willebrand disease screening On the Web |
American Roentgen Ray Society Images of Von Willebrand disease screening |
Risk calculators and risk factors for Von Willebrand disease screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Screening
Symptom/score | -1 | 0 | 1 | 2 | 3 | 4 |
---|---|---|---|---|---|---|
Epistaxis | - | No or trivial (≤5 per
year) |
>5 per year OR >10
minutes duration |
Consultation only | Packing, cauterization or
antifibrinolytics |
Blood transfusion, replacement
therapy or desmopressin |
Cutaneous | - | No or trivial (≤1cm) | >1cm AND no trauma | Consultation only | - | - |
Minor wounds | - | No or trivial (≤5 per
year) |
>5 per year OR >5
minutes duration |
Consultation only or Steristrips | Surgical hemostasis or
antifibrinolytics |
Blood transfusion, replacement
therapy or desmopressin |
Oral cavity | - | No | Reported at least once | Consultation only | Surgical hemostasis or
antifibrinolytics |
Blood transfusion, replacement
therapy or desmopressin |
Gastrointestinal
tract |
- | No | Identified cause | Consultation or spontaneous | Surgical hemostasis,
antifibrinolytics, blood transfusion, replacement therapy or desmopressin |
- |
Tooth extraction | No bleeding in at least
2 extractions |
None done or no
bleeding in 1 extraction |
Reported, no
consultation |
Consultation only | Resuturing, repacking or
antifibrinolytic |
Blood transfusion, replacement
therapy or desmopressin |
Surgery | No bleeding in at least
2 surgeries |
None done or no
bleeding in 1 |
Reported, no
consultation |
Consultation only | Surgical hemostasis or
antifibrinolytics |
Blood transfusion, replacement
therapy or desmopressin |
Menorrhagia | - | No | Reported or consultation
only |
Antifibrinolytics or
contraceptive pill use |
D&C or iron therapy | Blood transfusion, replacement
therapy or desmopressin |
Post-partum | No bleeding in at least
2 deliveries |
No deliveries or no
bleeding in 1 delivery |
Reported or consultation
only |
D&C, iron therapy or
antifibrinolytics |
Blood transfusion, replacement
therapy or desmopressin |
- |
Muscle hematoma | - | Never | Post-trauma, no therapy | Spontaneous, no therapy | Spontaneous or traumatic,
requiring replacement therapy or desmopressin |
Spontaneous or traumatic,
requiring surgical intervention or blood transfusion |
Hemarthrosis | - | Never | Post-trauma, no therapy | Spontaneous, no therapy | Spontaneous or traumatic,
requiring replacement therapy or desmopressin |
Spontaneous or traumatic,
requiring surgical intervention or blood transfusion |
Central nervous
system |
- | Never | - | - | Subdural, any intervention | Intracerebral, any intervention |
Other * | - | No | Reported | Consultation only | Surgical hemostasis,
antifibrinolytics or iron therapy |
Blood transfusion, replacement
therapy or desmopressin |
Scoring key for the Pediatric Bleeding Questionnaire. In the last row, the symptoms included in the "Other" category are umbilical stump bleeding, cephalhematoma, post-circumcision bleeding, post-venipuncture bleeding, and macroscopic hematuria