Primary sclerosing cholangitis overview: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
Primary sclerosing cholangitis is a relatively rare disease, with the incidence ranging from 0 to 1.3 per 100,000 cases and prevalence of 0 to 16.2 per 100,000 cases. The disease primarily affects young adult males and the mean age at diagnosis is 41 years. | |||
==Risk Factors== | ==Risk Factors== | ||
Revision as of 15:03, 15 December 2016
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Primary sclerosing cholangitis Microchapters |
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Differentiating Primary sclerosing cholangitis from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Primary sclerosing cholangitis overview On the Web |
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American Roentgen Ray Society Images of Primary sclerosing cholangitis overview |
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Directions to Hospitals Treating Primary sclerosing cholangitis |
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Risk calculators and risk factors for Primary sclerosing cholangitis overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Historical Perspective
Due to the rarity of the disease, primary sclerosing cholangitis has not been well studied in the past and cases were reported as individual cases. The first case of primary sclerosing cholangitis was documented in 1924.
Classification
Primary sclerosing cholangitis may be classified according to the size of bile ducts involved, as well as its association with autoimmune hepatitis. The 3 main subtypes are the classic subtype, small ducts subtype and primary sclerosing cholangitis associated with autoimmune hepatitis.
Pathophysiology
Causes
The cause of primary sclerosing cholangitis is unclear and not fully understood. However, genetic and environmental factors are thought to contribute to the development of the disease.
Differentiating primary sclerosing cholangitis from Other Diseases
Primary sclerosing cholangitis must be differentiated from causes of secondary sclerosing cholangitis.
Epidemiology and Demographics
Primary sclerosing cholangitis is a relatively rare disease, with the incidence ranging from 0 to 1.3 per 100,000 cases and prevalence of 0 to 16.2 per 100,000 cases. The disease primarily affects young adult males and the mean age at diagnosis is 41 years.