Churg-Strauss syndrome classification: Difference between revisions
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==Classification== | ==Classification== | ||
According to the 2012 Revised International Chapel Hill Consensus Conference on Nomenclature of Vasculitides | According to the 2012 Revised International Chapel Hill Consensus Conference on Nomenclature of Vasculitides<ref name="pmid23045170">{{cite journal| author=Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F et al.| title=2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. | journal=Arthritis Rheum | year= 2013 | volume= 65 | issue= 1 | pages= 1-11 | pmid=23045170 | doi=10.1002/art.37715 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23045170 }} </ref>, Eosinophilic Granulomatosis with Polyangitis (formerly known as Churg-Strauss' syndrome) can be considered a variant of the ANCA associated vasculitides of the small vessels. The Chapel Hill Consensus Conference however does not propose any diagnostic or classification criteria. Therefore, the diagnostic criteria proposed by the American College of Rheumatology (ACR) in 1990 on Eosinophilic granulomatosis with polyangiitis is still being use. | ||
The presence of 4 out of the 6 diagnostic criteria has a reported sensitivity of 85% and a specificity of 99.7% for the diagnosis of Eosinophilic granulomatosis with polyangiitis<ref name="pmid2202307">{{cite journal| author=Masi AT, Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP et al.| title=The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). | journal=Arthritis Rheum | year= 1990 | volume= 33 | issue= 8 | pages= 1094-100 | pmid=2202307 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2202307 }}</ref> | The presence of 4 out of the 6 diagnostic criteria has a reported sensitivity of 85% and a specificity of 99.7% for the diagnosis of Eosinophilic granulomatosis with polyangiitis<ref name="pmid2202307">{{cite journal| author=Masi AT, Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP et al.| title=The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). | journal=Arthritis Rheum | year= 1990 | volume= 33 | issue= 8 | pages= 1094-100 | pmid=2202307 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2202307 }}</ref><ref name="pmid25404930">{{cite journal| author=Gioffredi A, Maritati F, Oliva E, Buzio C| title=Eosinophilic granulomatosis with polyangiitis: an overview. | journal=Front Immunol | year= 2014 | volume= 5 | issue= | pages= 549 | pmid=25404930 | doi=10.3389/fimmu.2014.00549 | pmc=4217511 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25404930 }} </ref>. They are: | ||
{| class="wikitable" | {| class="wikitable" | ||
!American College of Rheumatology (ACR) Classification of Eosinophilic granulomatosis with polyangiitis | !American College of Rheumatology (ACR) Classification of Eosinophilic granulomatosis with polyangiitis | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
According to the American College of Rheumatology (ACR), Eosinophilic granulomatosis with polyangiitis is classified using 6 criteria.
Classification
According to the 2012 Revised International Chapel Hill Consensus Conference on Nomenclature of Vasculitides[1], Eosinophilic Granulomatosis with Polyangitis (formerly known as Churg-Strauss' syndrome) can be considered a variant of the ANCA associated vasculitides of the small vessels. The Chapel Hill Consensus Conference however does not propose any diagnostic or classification criteria. Therefore, the diagnostic criteria proposed by the American College of Rheumatology (ACR) in 1990 on Eosinophilic granulomatosis with polyangiitis is still being use.
The presence of 4 out of the 6 diagnostic criteria has a reported sensitivity of 85% and a specificity of 99.7% for the diagnosis of Eosinophilic granulomatosis with polyangiitis[2][3]. They are:
| American College of Rheumatology (ACR) Classification of Eosinophilic granulomatosis with polyangiitis |
|---|
| Asthma |
| Eosinophilia > 10% |
| Neuropathy (mononeuropathy or polyneuropathy) |
| Pulmonary infiltrate, non fixed |
| Paranasal sinus abnormality |
| Biopsy that shows extravascular eosinophil infiltration |
4 out of the 6 criteria are needed to distinguish Eosinophilic granulomatosis with polyangiitis from other vasculitides.
References
- ↑ Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F; et al. (2013). "2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides". Arthritis Rheum. 65 (1): 1–11. doi:10.1002/art.37715. PMID 23045170.
- ↑ Masi AT, Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP; et al. (1990). "The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis)". Arthritis Rheum. 33 (8): 1094–100. PMID 2202307.
- ↑ Gioffredi A, Maritati F, Oliva E, Buzio C (2014). "Eosinophilic granulomatosis with polyangiitis: an overview". Front Immunol. 5: 549. doi:10.3389/fimmu.2014.00549. PMC 4217511. PMID 25404930.