Cystitis secondary prevention: Difference between revisions

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The secondary Prevention of Cystitis includes the prophylaxis to prevent recurrent cystitis.
The secondary Prevention of Cystitis includes the prophylaxis to prevent recurrent cystitis.
===Antimicrobial Prophylaxis===
===Antimicrobial Prophylaxis===
*Prophylactic therapy using antimicrobial agents may be considered among women with recurrent episodes of cystitis that are associated with sexual activity.
*Prophylaxis is require din individuals having two or more episodes in 6 months or three or more episodes in 12 months period.<ref name="pmid3333659">{{cite journal| author=Nicolle LE, Ronald AR| title=Recurrent urinary tract infection in adult women: diagnosis and treatment. | journal=Infect Dis Clin North Am | year= 1987 | volume= 1 | issue= 4 | pages= 793-806 | pmid=3333659 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3333659  }} </ref><ref name="pmid3077293">{{cite journal| author=Ronald AR, Conway B| title=An approach to urinary tract infections in ambulatory women. | journal=Curr Clin Top Infect Dis | year= 1988 | volume= 9 | issue=  | pages= 76-125 | pmid=3077293 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3077293  }} </ref>
*Prophylactic therapy using antimicrobial agents may be considered as either continuously or postcoital prophylaxis for 6 to 12 months.
*The following regimens may be used as single doses prior to sexual activity.<ref name="pmid21292654">{{cite journal| author=Gupta K, Hooton TM, Naber KG, Wullt B, Colgan R, Miller LG et al.| title=International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. | journal=Clin Infect Dis | year= 2011 | volume= 52 | issue= 5 | pages= e103-20 | pmid=21292654 | doi=10.1093/cid/ciq257 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21292654  }} </ref>
*The following regimens may be used as single doses prior to sexual activity.<ref name="pmid21292654">{{cite journal| author=Gupta K, Hooton TM, Naber KG, Wullt B, Colgan R, Miller LG et al.| title=International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. | journal=Clin Infect Dis | year= 2011 | volume= 52 | issue= 5 | pages= e103-20 | pmid=21292654 | doi=10.1093/cid/ciq257 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21292654  }} </ref>
*'''Prophylactic Therapy''':
*'''Prophylactic Therapy''':
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:*Alternative regimen (3): [[Norfloxacin]] 400 mg PO bid in a single dose
:*Alternative regimen (3): [[Norfloxacin]] 400 mg PO bid in a single dose
:*Alternative regimen (4): [[Gatifloxacin]] 200 mg PO qd in a single dose
:*Alternative regimen (4): [[Gatifloxacin]] 200 mg PO qd in a single dose
*[[Nitrofurantoin]] and [[Fosfomycin]] effective for use as long term prophylaxis.<ref name="pmid9786476">{{cite journal| author=Brumfitt W, Hamilton-Miller JM| title=Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years' experience. | journal=J Antimicrob Chemother | year= 1998 | volume= 42 | issue= 3 | pages= 363-71 | pmid=9786476 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9786476  }} </ref><ref name="pmid16080282">{{cite journal| author=Rudenko N, Dorofeyev A| title=Prevention of recurrent lower urinary tract infections by long-term administration of fosfomycin trometamol. Double blind, randomized, parallel group, placebo controlled study. | journal=Arzneimittelforschung | year= 2005 | volume= 55 | issue= 7 | pages= 420-7 | pmid=16080282 | doi=10.1055/s-0031-1296881 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16080282  }} </ref>


==References==
==References==

Revision as of 21:34, 13 January 2017

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Overview

Secondary prophylaxis of Cystitis is useful to prevent recurrent cystitis. It is more beneficial in patients in which Cystitis is associated with sexual intercourse, a structural defect or a disease like Diabetes that can lead to recurrent infections.

Secondary Prevention

The secondary Prevention of Cystitis includes the prophylaxis to prevent recurrent cystitis.

Antimicrobial Prophylaxis

  • Prophylaxis is require din individuals having two or more episodes in 6 months or three or more episodes in 12 months period.[1][2]
  • Prophylactic therapy using antimicrobial agents may be considered as either continuously or postcoital prophylaxis for 6 to 12 months.
  • The following regimens may be used as single doses prior to sexual activity.[3]
  • Prophylactic Therapy:
  • Preferred regimen (1): Fosfomycin tromethamine 3 g PO in a single dose
  • Preferred regimen (2): Nitrofurantoin monohydrate/macrocrystals 100 mg PO in a single dose
  • Preferred regimen (3): Trimethoprim-Sulfamethoxazole 160/800 mg PO double-strength tablet bid in a single dose
  • Preferred regimen (4): Trimethoprim 100 mg PO bid in a single dose
  • Alternative regimen (1): Ciprofloxacin 250 mg PO bid in a single dose
  • Alternative regimen (2): Levofloxacin 250 mg PO qd in a single dose
  • Alternative regimen (3): Norfloxacin 400 mg PO bid in a single dose
  • Alternative regimen (4): Gatifloxacin 200 mg PO qd in a single dose

References

  1. Nicolle LE, Ronald AR (1987). "Recurrent urinary tract infection in adult women: diagnosis and treatment". Infect Dis Clin North Am. 1 (4): 793–806. PMID 3333659.
  2. Ronald AR, Conway B (1988). "An approach to urinary tract infections in ambulatory women". Curr Clin Top Infect Dis. 9: 76–125. PMID 3077293.
  3. Gupta K, Hooton TM, Naber KG, Wullt B, Colgan R, Miller LG; et al. (2011). "International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases". Clin Infect Dis. 52 (5): e103–20. doi:10.1093/cid/ciq257. PMID 21292654.
  4. Brumfitt W, Hamilton-Miller JM (1998). "Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years' experience". J Antimicrob Chemother. 42 (3): 363–71. PMID 9786476.
  5. Rudenko N, Dorofeyev A (2005). "Prevention of recurrent lower urinary tract infections by long-term administration of fosfomycin trometamol. Double blind, randomized, parallel group, placebo controlled study". Arzneimittelforschung. 55 (7): 420–7. doi:10.1055/s-0031-1296881. PMID 16080282.

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