Septic arthritis causes: Difference between revisions

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===Common Causes===
===Common Causes===
Gram-negative bacilli account for 10 to 20% of septic arthritis causes.<ref name="pmid2283490">Deesomchok U, Tumrasvin T (1990) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=2283490 Clinical study of culture-proven cases of non-gonococcal arthritis.] ''J Med Assoc Thai'' 73 (11):615-23. PMID: [https://pubmed.gov/2283490 2283490]</ref> ~10% of patients with nongonococcal septic arthritis are due to polymicrobial cause of infections. Anaerobes are also can cause septic arthritis in few cases. Most common cause of septic arthritis in children age < 2 years are Haemophilus influenzae (in immunized children), Staph. aureus, group A Streptococcal infections and Kingella kingae.<ref name="pmid7735407">Yagupsky P, Bar-Ziv Y, Howard CB, Dagan R (1995) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=7735407 Epidemiology, etiology, and clinical features of septic arthritis in children younger than 24 months.] ''Arch Pediatr Adolesc Med'' 149 (5):537-40. PMID: [https://pubmed.gov/7735407 7735407]</ref> The source of infection in most of the cases (~50%) often from the skin, lungs or bladder.
*[[Brucella]] <ref name=Axford>{{cite book |author=O'Callaghan C, Axford JS |title=Medicine |publisher=Blackwell Science |location=Oxford |year=2004 |pages= |isbn=0-632-05162-0 |edition=2nd ed.}}</ref>
*[[Brucella]] <ref name=Axford>{{cite book |author=O'Callaghan C, Axford JS |title=Medicine |publisher=Blackwell Science |location=Oxford |year=2004 |pages= |isbn=0-632-05162-0 |edition=2nd ed.}}</ref>
*[[Escherichia coli]]
*[[Escherichia coli]]
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Septic arthritis is due to intra articular seeding of living microorganisms.<ref name="pmid8412643">Dubost JJ, Fis I, Denis P, Lopitaux R, Soubrier M, Ristori JM et al. (1993) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=8412643 Polyarticular septic arthritis.] ''Medicine (Baltimore)'' 72 (5):296-310. PMID: [https://pubmed.gov/8412643 8412643]</ref> The most common etiological agent of all nongonococcal causes of septic arthritis in the United States is Staphylococcus aureus.<ref name="pmid2283490">Deesomchok U, Tumrasvin T (1990) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=2283490 Clinical study of culture-proven cases of non-gonococcal arthritis.] ''J Med Assoc Thai'' 73 (11):615-23. PMID: [https://pubmed.gov/2283490 2283490]</ref>
Septic arthritis is due to intra articular seeding of living microorganisms.<ref name="pmid8412643">Dubost JJ, Fis I, Denis P, Lopitaux R, Soubrier M, Ristori JM et al. (1993) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=8412643 Polyarticular septic arthritis.] ''Medicine (Baltimore)'' 72 (5):296-310. PMID: [https://pubmed.gov/8412643 8412643]</ref> The most common etiological agent of all nongonococcal causes of septic arthritis in the United States is Staphylococcus aureus.<ref name="pmid2283490">Deesomchok U, Tumrasvin T (1990) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=2283490 Clinical study of culture-proven cases of non-gonococcal arthritis.] ''J Med Assoc Thai'' 73 (11):615-23. PMID: [https://pubmed.gov/2283490 2283490]</ref>
Gram-negative bacilli account for 10 to 20% of septic arthritis causes.<ref name="pmid2283490">Deesomchok U, Tumrasvin T (1990) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=2283490 Clinical study of culture-proven cases of non-gonococcal arthritis.] ''J Med Assoc Thai'' 73 (11):615-23. PMID: [https://pubmed.gov/2283490 2283490]</ref> ~10% of patients with nongonococcal septic arthritis are due to polymicrobial cause of infections. Anaerobes are also can cause septic arthritis in few cases.
Most common cause of septic arthritis in children age < 2 years are Haemophilus influenzae (in immunized children), Staph. aureus, group A Streptococcal infections and Kingella kingae.<ref name="pmid7735407">Yagupsky P, Bar-Ziv Y, Howard CB, Dagan R (1995) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=7735407 Epidemiology, etiology, and clinical features of septic arthritis in children younger than 24 months.] ''Arch Pediatr Adolesc Med'' 149 (5):537-40. PMID: [https://pubmed.gov/7735407 7735407]</ref>
The source of infection in most of the cases (~50%) often from the skin, lungs or bladder.


Causes of infection include
Causes of infection include

Revision as of 21:02, 24 January 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Jumana Nagarwala, M.D., Senior Staff Physician, Department of Emergency Medicine, Henry Ford Hospital; Cafer Zorkun, M.D., Ph.D. [2]

Overview

Septic arthritis develops when bacteria or other tiny disease-causing organisms (microorganisms) spread through the bloodstream to a joint. It may also occur when the joint is directly infected with a microorganism from an injury or during surgery. The most common sites for this type of infection are the knee and hip. Most cases of acute septic arthritis are caused by bacteria such as staphylococcus or streptococcus. Chronic septic arthritis (which is less common) is caused by organisms such as Mycobacterium tuberculosis and Candida albicans.Gram-negative bacilli account for 10 to 20% of septic arthritis causes.[1] ~10% of patients with nongonococcal septic arthritis are due to polymicrobial cause of infections. Anaerobes are also can cause septic arthritis in few cases.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Gram-negative bacilli account for 10 to 20% of septic arthritis causes.[1] ~10% of patients with nongonococcal septic arthritis are due to polymicrobial cause of infections. Anaerobes are also can cause septic arthritis in few cases. Most common cause of septic arthritis in children age < 2 years are Haemophilus influenzae (in immunized children), Staph. aureus, group A Streptococcal infections and Kingella kingae.[2] The source of infection in most of the cases (~50%) often from the skin, lungs or bladder.

Septic arthritis is due to intra articular seeding of living microorganisms.[7] The most common etiological agent of all nongonococcal causes of septic arthritis in the United States is Staphylococcus aureus.[1]

Causes of infection include

  1. Hematogenous dissemination
  2. Post operative wound infection such as after arthroscopic procedures
  3. Intra articular steriod injections
  4. Diagnostic punctures
  5. Open traumatc injury to the joint

Common organisms

  • Staphylococcus aureus
  • Streptococcal pyogenous
  • Streptococcal pneumonia
  • Escherichia coli
  • Staphylococcus epidermidis
  • Borrelia burgdorferi

Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease No underlying causes
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes


Causes in Alphabetical Order

References

  1. ↑ 1.0 1.1 1.2 Deesomchok U, Tumrasvin T (1990) Clinical study of culture-proven cases of non-gonococcal arthritis. J Med Assoc Thai 73 (11):615-23. PMID: 2283490
  2. ↑ Yagupsky P, Bar-Ziv Y, Howard CB, Dagan R (1995) Epidemiology, etiology, and clinical features of septic arthritis in children younger than 24 months. Arch Pediatr Adolesc Med 149 (5):537-40. PMID: 7735407
  3. ↑ 3.0 3.1 3.2 O'Callaghan C, Axford JS (2004). Medicine (2nd ed. ed.). Oxford: Blackwell Science. ISBN 0-632-05162-0.
  4. ↑ Bowerman SG, Green NE, Mencio GA (1997). "Decline of bone and joint infections attributable to haemophilus influenzae type b". Clin Orthop Relat Res. (341): 128–33. PMID 9269165. Unknown parameter |month= ignored (help)
    Peltola H, Kallio MJ, Unkila-Kallio L (1998). "Reduced incidence of septic arthritis in children by Haemophilus influenzae type-b vaccination. Implications for treatment". J Bone Joint Surg Br. 80 (3): 471–3. PMID 9619939. Unknown parameter |month= ignored (help)
  5. ↑ 5.0 5.1 Kaandorp CJ, Dinant HJ, van de Laar MA, Moens HJ, Prins AP, Dijkmans BA (1997). "Incidence and sources of native and prosthetic joint infection: a community based prospective survey". Ann Rheum Dis. 56 (8): 470–5. PMC 1752430. PMID 9306869. Unknown parameter |month= ignored (help)
    Weston VC, Jones AC, Bradbury N, Fawthrop F, Doherty M (1999). "Clinical features and outcome of septic arthritis in a single UK Health District 1982-1991". Ann Rheum Dis. 58 (4): 214–9. PMC 1752863. PMID 10364899. Unknown parameter |month= ignored (help)
  6. ↑ Topics in Infectious Diseases Newsletter, August 2001, Pseudomonas aeruginosa.
  7. ↑ Dubost JJ, Fis I, Denis P, Lopitaux R, Soubrier M, Ristori JM et al. (1993) Polyarticular septic arthritis. Medicine (Baltimore) 72 (5):296-310. PMID: 8412643


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