Fungal meningitis epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
While cryptococccus and candida infections occur worldwide, other [[fungal infections]] tend to cluster in specific geographical regions. The most common cause of [[fungal meningitis]] is ''[[Cryptococcus neoformans]]''. | While cryptococccus and candida infections occur worldwide, other [[fungal infections]] tend to cluster in specific geographical regions.<ref name="pmid17921648">{{cite journal| author=Shankar SK, Mahadevan A, Sundaram C, Sarkar C, Chacko G, Lanjewar DN et al.| title=Pathobiology of fungal infections of the central nervous system with special reference to the Indian scenario. | journal=Neurol India | year= 2007 | volume= 55 | issue= 3 | pages= 198-215 | pmid=17921648 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17921648 }} </ref><ref name="pmid11051295">{{cite journal| author=Gottfredsson M, Perfect JR| title=Fungal meningitis. | journal=Semin Neurol | year= 2000 | volume= 20 | issue= 3 | pages= 307-22 | pmid=11051295 | doi=10.1055/s-2000-9394 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11051295 }} </ref> | ||
The most common cause of [[fungal meningitis]] is ''[[Cryptococcus neoformans]]''. | |||
==Epidemiology== | ==Epidemiology== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby; Prince Tano Djan, BSc, MBChB [2]
Overview
While cryptococccus and candida infections occur worldwide, other fungal infections tend to cluster in specific geographical regions.[1][2]
The most common cause of fungal meningitis is Cryptococcus neoformans.
Epidemiology
Cryptococcus Meningitis
- It is the most common cause of fungal meningitis.
- Cryptococcus meningitis occurs worldwide but it is highly prevalent in southeast Asia and southern and east Africa where the prevalence of HIV is elevated.[3]
- It is a common opportunistic infection in patients with HIV and it is considered as an AIDS defining lesion. [4]
- The mortality is high (10-30%).[5]
Geographic Distribution of Endemic Fungi in The United States
- Blastomyces dermatiditis: Midwest and southeast of USA
- Coccidiodes immitis: Southwest of USA
- Histoplasma Capsulatum: Ohio, central Mississippi River Valley[6]
References
- ↑ Shankar SK, Mahadevan A, Sundaram C, Sarkar C, Chacko G, Lanjewar DN; et al. (2007). "Pathobiology of fungal infections of the central nervous system with special reference to the Indian scenario". Neurol India. 55 (3): 198–215. PMID 17921648.
- ↑ Gottfredsson M, Perfect JR (2000). "Fungal meningitis". Semin Neurol. 20 (3): 307–22. doi:10.1055/s-2000-9394. PMID 11051295.
- ↑ Holmes CB, Losina E, Walensky RP, Yazdanpanah Y, Freedberg K (2003) Review of human immunodeficiency virus type 1-related opportunistic infections in Sub-Saharan Africa. Clin Infect Dis, 36, 652–662.
- ↑ Chariyalertsak S, Sirisanthana T, Saengwonloey O, Nelson K (2001) Clinical presentation and risk behaviors of patients with acquired immunodeficiency syndrome in Thailand, 1994–1998: Regional variation and temporal trends. Clin Infect Dis, 32, 955–962.
- ↑ Van der Horst CM, Saag MS, Cloud GA et al. (1997) Treatment of cryptococcal meningitis associated with the acquired immunodeficiency syndrome. N Engl J Med, 337, 15–21.
- ↑ Koroshetz WJ. Chapter 382. Chronic and Recurrent Meningitis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison's Principles of Internal Medicine. 18th ed. New York: McGraw-Hill; 2012.