Tropical sprue pathophysiology: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 10: | Line 10: | ||
==Histology== | ==Histology== | ||
The histological changes of TS include: Flattening of the villi and small intestinal inflammation which are similar to an [[autoimmune disorder]] Coeliac disease (also known as ''[[coeliac sprue]]''). A complete flattening of the villi on small bowel biopsy is an uncommon finding in TS unlike Celiac disease. | The histological changes of TS include: Flattening of the villi and small intestinal inflammation which are similar to an [[autoimmune disorder]] Coeliac disease (also known as ''[[coeliac sprue]]''). A complete flattening of the villi on small bowel biopsy is an uncommon finding in TS unlike Celiac disease. | ||
{| class="wikitable" | |||
!Diagnosis | |||
!Villous morphology | |||
!Findings in Lamina propria | |||
!Involved portion of the GI tract | |||
|- | |||
|Tropical sprue | |||
|Mild to moderate blunting of the villi with an increased number of Intraepithelial lymphocytes. | |||
|Increased number of plasma cells and eosinophils. | |||
|Ileum > Duodenum > Colon | |||
|- | |||
|Celiac sprue | |||
|Variable, often there is a complete flattening of the villi. Always there is an increased number of Intraepithelial lymphocytes | |||
|Plasma cells > Eosinophils > Neutrophils. | |||
|Duodenum > Ileum. | |||
|} | |||
==References== | ==References== | ||
Revision as of 19:24, 15 February 2017
|
Tropical sprue Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Tropical sprue pathophysiology On the Web |
|
American Roentgen Ray Society Images of Tropical sprue pathophysiology |
|
Risk calculators and risk factors for Tropical sprue pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Overview
Pathophysiology
Histology
The histological changes of TS include: Flattening of the villi and small intestinal inflammation which are similar to an autoimmune disorder Coeliac disease (also known as coeliac sprue). A complete flattening of the villi on small bowel biopsy is an uncommon finding in TS unlike Celiac disease.
| Diagnosis | Villous morphology | Findings in Lamina propria | Involved portion of the GI tract |
|---|---|---|---|
| Tropical sprue | Mild to moderate blunting of the villi with an increased number of Intraepithelial lymphocytes. | Increased number of plasma cells and eosinophils. | Ileum > Duodenum > Colon |
| Celiac sprue | Variable, often there is a complete flattening of the villi. Always there is an increased number of Intraepithelial lymphocytes | Plasma cells > Eosinophils > Neutrophils. | Duodenum > Ileum. |