Tropical sprue differential diagnosis: Difference between revisions
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'''Differentiating Tropical sprue from other causes of Tropical malabsorption''' | '''Differentiating Tropical sprue from other causes of Tropical malabsorption''' | ||
! colspan="2" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Causes}} | ! colspan="2" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Causes}} | ||
!colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Pathophysiology and Histology}} | !colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Pathophysiology and Histology}} | ||
!colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Acute diarrhea}} | !colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Acute diarrhea}} | ||
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! colspan="2" |Tropical sprue | ! colspan="2" |Tropical sprue | ||
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! | ! | ||
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! colspan="2" |Tropical Enteropathy | |||
!Increased mucosal permeability, shorter villi, elongated crypts and increased lymphocytes in the lamina propria | |||
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!Subclinical | |||
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! rowspan="4" | '''Infectious''' | ! rowspan="4" | '''Infectious''' | ||
!Protozoal | !Protozoal | ||
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* | * | ||
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!Helminths | !Helminths | ||
! | ! | ||
! | ! | ||
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!Bacterial | !Bacterial | ||
! | ! | ||
! | ! | ||
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!Viral | !Viral | ||
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! rowspan="3" |Inflammatory and Immune mediated | ! rowspan="3" |Inflammatory and Immune mediated | ||
!Crohn's disease | !Crohn's disease | ||
! | !Decreased small intestinal absorptive surface area | ||
! | ! | ||
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!Ulcerative colitis | !Ulcerative colitis | ||
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!Coeliac sprue | !Coeliac sprue | ||
! | !Complete villous atrophy of the jejunal mucosa | ||
! | ! | ||
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| | |Antiendomysial and tissue transglutaminase antibodies | ||
| | |Clinical and histological response to gluten withdrawal. | ||
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!Malignant | !Malignant | ||
!Intestinal Lymphoma | !Intestinal Lymphoma | ||
! | ! | ||
! | ! | ||
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! colspan="2" |Pancreatic disease | ! colspan="2" |Pancreatic disease | ||
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! colspan="2" |Irritable bowel syndrome | ! colspan="2" |Irritable bowel syndrome | ||
! | ! | ||
! | ! |
Revision as of 16:29, 21 February 2017
Tropical sprue Microchapters |
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Risk calculators and risk factors for Tropical sprue differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Tropical sprue must be differentiated from celiac disease, chronic diarrhea, Clonorchiasis, traveler's diarrhea, and whipworm.
Differentiating Tropical sprue from other Diseases
Causes | Pathophysiology and Histology | Acute diarrhea | Traveller's diarrhea | Chronic diarrhea | Malabsorption | Steatorrhoea | Diagnosis | Confirmatory tests | Associations | |
---|---|---|---|---|---|---|---|---|---|---|
Tropical sprue | ||||||||||
Tropical Enteropathy | Increased mucosal permeability, shorter villi, elongated crypts and increased lymphocytes in the lamina propria | Subclinical | ||||||||
Infectious | Protozoal |
|
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Helminths | ||||||||||
Bacterial | ||||||||||
Viral | ||||||||||
Inflammatory and Immune mediated | Crohn's disease | Decreased small intestinal absorptive surface area | ||||||||
Ulcerative colitis | ||||||||||
Coeliac sprue | Complete villous atrophy of the jejunal mucosa | Antiendomysial and tissue transglutaminase antibodies | Clinical and histological response to gluten withdrawal. | |||||||
Malignant | Intestinal Lymphoma | |||||||||
Pancreatic disease | ||||||||||
Irritable bowel syndrome |
Chronic diarrhea
- Tropical sprue
- Ulcerative Colitis,
- Crohn's disease
- Diarrhea, chronic responsive to antiparasitic drugs
- Diarrhea, chronic unknown
- Inflammatory bowel disease, new onset post-travel (Crohn or ulcerative colitis)
- Irritable bowel syndrome
- Irritable bowel syndrome, post infectious
- Lactose intolerance, post infectious
- Malabsorption
Acute diarrhea
- E. coli
- Clostridium difficile-associated disease
- Campylobacter
- Cholera (toxigenic Vibrio cholerae)
- Cryptosporidium
- Cyclospora
- Diarrhea, acute bacterial
- Diarrhea, acute parasitic
- Diarrhea, acute unspecified
- Diarrhea, acute viral
- Dysentery, acute unspecified
- Entamoeba histolytica, ameba
- E. histolytica, diarrhea
- E. histolytica, dysentery
- Food poisoning
- Gastroenteritis
- Giardia
- Isospora
- Noncholera Vibrio
- Salmonella, other
- Shiga toxin-producing Escherichia coli
- Shigella, S. boydii
- Shigella, S. dysenteriae
- Shigella, S. flexneri
The following diseases have a similar presentation to tropical sprue.
- Celiac Disease
- Chronic diarrhea
- Clonorchiasis
- Traveler's diarrhea
- Whipworm