Pyogenic liver abscess pathophysiology: Difference between revisions

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:*Retroperitoneal extension from appendix (suppurative appendicitis most frequent source of infection)
:*Retroperitoneal extension from appendix (suppurative appendicitis most frequent source of infection)
*Ascending biliary infection is the most common source of pyogenic liver abscess
*Ascending biliary infection is the most common source of pyogenic liver abscess
*Bacteria involved in pyogenic liver abscess include:
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{{familytree | | | C01 | | | | C02 | | | | C03 | | | | C04 |C01=[[Gram-positive]] [[aerobes]]|C02=[[Gram-negative]] enterics|C03=[[Anaerobic]] organisms|C04=[[Acid fast|Acid fast bacilli]]}}
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{{familytree | | | D01 | | | | D02 | | | | D03 | | | | D04 | D01=[[Streptococcus|Streptococcus sp]] <br> ''[[Staphylococcus aureus]]'' / ''[[Staphylococcus epidermidis]]'' <br> ''[[Actinomyces|Actinomyces sp]] <br>[[Enterococcus|Enterococcus sp]] <br> ''[[Streptococcus milleri]]''|D02=''[[Escherichia coli]]'' <br> ''[[Salmonella typhi]]'' <br> ''[[Yersinia enterocolitica]]'' <br> ''[[Klebsiella|K.pneumonia]]'' <br> [[Pseudomonas|Pseudomonas sp]] <br> [[Proteus|Proteus sp]] <br> ''[[Eikenella corrodens]]'' <br> Others|D03=[[Bacteroides|Bacteroids sp]] <br> [[Fusobacterium]] <br> [[Anaerobic]]/ [[Microaerophilic]] [[streptococci]] <br> Other [[anaerobes]]|D04=''[[Mycobacterium tuberculosis]]''}}
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==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 19:47, 21 February 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Pathophysiology

  • Development of pyogenic liver abscess is the result of extension of infection through the following:[1]
  • Portal vein
  • Hepatic arteries as metastatic abscessess
  • Direct spread from nearby infection
  • Trauma
  • Retroperitoneal extension from appendix (suppurative appendicitis most frequent source of infection)
  • Ascending biliary infection is the most common source of pyogenic liver abscess
  • Bacteria involved in pyogenic liver abscess include:
 
 
 
 
 
 
 
 
 
 
 
Pyogenic liver abscess
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Bacteria
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Gram-positive aerobes
 
 
 
Gram-negative enterics
 
 
 
Anaerobic organisms
 
 
 
Acid fast bacilli
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Streptococcus sp
Staphylococcus aureus / Staphylococcus epidermidis
Actinomyces sp
Enterococcus sp
Streptococcus milleri
 
 
 
Escherichia coli
Salmonella typhi
Yersinia enterocolitica
K.pneumonia
Pseudomonas sp
Proteus sp
Eikenella corrodens
Others
 
 
 
Bacteroids sp
Fusobacterium
Anaerobic/ Microaerophilic streptococci
Other anaerobes
 
 
 
Mycobacterium tuberculosis

References

  1. Munro JC (1905). "VII. Lymphatic and Hepatic Infections Secondary to Appendicitis". Ann Surg. 42 (5): 692–734. PMC 1425980. PMID 17861705.