Actinomycosis differential diagnosis: Difference between revisions
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
Actinomycosis should be differentiated from:<ref name="pmid17560191">{{cite journal| author=Yiğiter M, Kiyici H, Arda IS, Hiçsönmez A| title=Actinomycosis: a differential diagnosis for appendicitis. A case report and review of the literature. | journal=J Pediatr Surg | year= 2007 | volume= 42 | issue= 6 | pages= E23-6 | pmid=17560191 | doi=10.1016/j.jpedsurg.2007.03.057 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17560191 }} </ref> | |||
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!Disease | !Disease | ||
Revision as of 21:28, 9 March 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The differential diagnosis of actinomycosis consists of blastomycosis, brain abscess, colon cancer, crohn disease, diverticulitis, liver abscess, lung abscess, lymphoma, nocardiosis, pelvic inflammatory disease, pneumonia, tuberculosis and uterine cancer.
Differential Diagnosis
Actinomycosis should be differentiated from:[1]
| Disease | Differentiating signs/symptoms | Differentiating tests |
|---|---|---|
| Abdominal Abscess | ||
| Nocardiosis | ||
| Ovarian/Oviductal tumor | ||
| Appendicitis | ||
| Blastomycosis | ||
| Brain abscess | ||
| Colon cancer | ||
| Gastric adenocarcinoma | ||
| Crohn disease | ||
| Ulcerative colitis | ||
| Diverticulitis | ||
| Liver abscess | ||
| Lung abscess | ||
| Lung cancer | ||
| Pelvic inflammatory disease | ||
| Pneumonia (fungal, bacterial, or aspiration) | ||
| Pulmonary tuberculosis | ||
| Intestinal tuberculosis | ||
| Uterine cancer | ||
| Whipple disease |
The clinical manifestations of actinomycosis and nocardiosis are similar. The following table helps in differentiating actinomycosis from nocardiosis.[2][3]
| Actinomycosis | Nocardiosis |
|---|---|
| Gram positive anaerobic species | Gram positive aerobe |
| Decreasing incidence | Increasing incidence |
| Occurs primarily in immunocompetent host | Occurs primarily in immunocompromised host |
| Predominant cervicofacial | Predominant pulmonary |
| Chest wall involvement and bony erosions are common | Chest wall involvement is uncommon |
| Granuloma formation and intense fibrosis are common. Form characteristic sulphur granules | Granuloma formation and fibrosis are uncommon |
| Spread by direct invasion | Metastatic spread is common (especially to brain) |
| Diagnosis is made through cytologic or histologic examination | Diagnosis is made through BAL (bronchoalveolar lavage),
sputum, or pleural fluid culture |
| Treatment: Penicillin
Treatment with antibiotics alone |
Treatment: Sulfonamides
Often need surgical drainage |
References
- ↑ Yiğiter M, Kiyici H, Arda IS, Hiçsönmez A (2007). "Actinomycosis: a differential diagnosis for appendicitis. A case report and review of the literature". J Pediatr Surg. 42 (6): E23–6. doi:10.1016/j.jpedsurg.2007.03.057. PMID 17560191.
- ↑ Sullivan DC, Chapman SW (2010). "Bacteria that masquerade as fungi: actinomycosis/nocardia". Proc Am Thorac Soc. 7 (3): 216–21. doi:10.1513/pats.200907-077AL. PMID 20463251.
- ↑ Warren NG (1996). "Actinomycosis, nocardiosis, and actinomycetoma". Dermatol Clin. 14 (1): 85–95. PMID 8821161.
de:Aktinomykose gl:Actinomicose hr:Aktinomikoza nl:Actinomycose sr:Актиномикоза fi:Aktinomykoosi uk:Актиномікоз