Celiac disease screening: Difference between revisions

Jump to navigation Jump to search
← Older editNewer edit →
VisualWikitext
Luke Rusowicz-Orazem (talk | contribs)
Bureaucrats, bureaucrats, editnews, interwiki, nocaptcha, nukepages, smwadministrator, Administrators, Widget editors
4,319 edits
No edit summary
Mehdi Pahlavani (talk | contribs)
Bureaucrats, bureaucrats, nocaptcha, Administrators
5,087 edits
No edit summary
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Celiac disease}}
{{Celiac disease}}
{{CMG}}
{{CMG}};{{AE}}{{MehdiP}}


==Overview==
==Overview==
Screening with tissue transglutaminase (tTG) IgA test is recommended for symptomatic high risk patients.
==Screening==
==Screening==
There is significant debate as to the benefits of [[Screening (medicine)|screening]]. Some studies suggest that early detection would decrease the risk of osteoporosis and anaemia. In contrast, a [[cohort study|cohort studied]] in Cambridge suggested that people with undetected coeliac disease had a beneficial risk profile for [[cardiovascular disease]] (less [[overweight]], lower [[cholesterol]] levels).
*Screening in asymptomatic persons is not recommended.<ref name="pmid28350935">{{cite journal |vauthors=Chou R, Bougatsos C, Blazina I, Mackey K, Grusing S, Selph S |title=Screening for Celiac Disease: Evidence Report and Systematic Review for the US Preventive Services Task Force |journal=JAMA |volume=317 |issue=12 |pages=1258–1268 |year=2017 |pmid=28350935 |doi=10.1001/jama.2016.10395 |url=}}</ref>
 
*Screening is recommended for symptomatic and high risk patients with positive family history in first and second degree relatives also in patients with other autoimmune diseases such as, type 1 diabetes mellitus, inflammatory luminal gastrointestinal disorders, Down syndrome, Turner syndrome, IgA deficiency, and IgA nephropathy.<ref name="pmid28350935">{{cite journal |vauthors=Chou R, Bougatsos C, Blazina I, Mackey K, Grusing S, Selph S |title=Screening for Celiac Disease: Evidence Report and Systematic Review for the US Preventive Services Task Force |journal=JAMA |volume=317 |issue=12 |pages=1258–1268 |year=2017 |pmid=28350935 |doi=10.1001/jama.2016.10395 |url=}}</ref>
Due to its high sensitivity, [[serology]] has been proposed as a screening measure, because the presence of antibodies would detect previously undiagnosed cases of coeliac disease and prevent its complications in those patients. Serology may also be used to monitor adherence to diet: in those who still ingest gluten, antibody levels remain elevated.
*Screening method for celiac disease is tissue transglutaminase (tTG) IgA test.
 
Clinical scenarios in which screening may be justified include type 1 diabetes unexplained iron-deficiency anemia,<ref>{{cite journal |author=Corazza G, Valentini R, Andreani M, D'Anchino M, Leva M, Ginaldi L, De Feudis L, Quaglino D, Gasbarrini G |title=Subclinical coeliac disease is a frequent cause of iron-deficiency anaemia |journal=Scand J Gastroenterol |volume=30 |issue=2 |pages=153–6 |year=1995 |pmid=7732338}}</ref><ref>{{cite journal |author=Ransford R, Hayes M, Palmer M, Hall M |title=A controlled, prospective screening study of celiac disease presenting as iron deficiency anemia |journal=J Clin Gastroenterol |volume=35 |issue=3 |pages=228&ndash;33 |year=2002 |pmid=12192198}}</ref> [[Down's syndrome]], [[Turner's syndrome]], [[irritable bowel syndrome]], [[Lupus erythematosus|lupus]], and autoimmune thyroid disease.<ref>{{cite journal |author=Sjöberg K, Carlsson A |title=Screening for celiac disease can be justified in high-risk groups |journal=Lakartidningen |volume=101 |issue=48 |pages=3912, 3915–6, 3918&ndash;9 |year=2004 |pmid=15631226}}</ref>
 
==References==
==References==


Line 17: Line 15:
{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category:Rheumatology]]
[[Category:Gastroentrology]]
[[Category:Needs content]]
[[Category:Needs overview]]]

Revision as of 16:14, 31 March 2017

Celiac disease Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Celiac disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Life Style Modifications
Pharmacotherapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Celiac disease screening On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Celiac disease screening

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

National Guidelines Clearinghouse

NICE Guidance

FDA on Celiac disease screening

CDC on Celiac disease screening

Celiac disease screening in the news

Blogs onCeliac disease screening

Directions to Hospitals Treating Celiac disease

Risk calculators and risk factors for Celiac disease screening

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

Screening with tissue transglutaminase (tTG) IgA test is recommended for symptomatic high risk patients.

Screening

  • Screening in asymptomatic persons is not recommended.[1]
  • Screening is recommended for symptomatic and high risk patients with positive family history in first and second degree relatives also in patients with other autoimmune diseases such as, type 1 diabetes mellitus, inflammatory luminal gastrointestinal disorders, Down syndrome, Turner syndrome, IgA deficiency, and IgA nephropathy.[1]
  • Screening method for celiac disease is tissue transglutaminase (tTG) IgA test.

References

  1. ↑ 1.0 1.1 Chou R, Bougatsos C, Blazina I, Mackey K, Grusing S, Selph S (2017). "Screening for Celiac Disease: Evidence Report and Systematic Review for the US Preventive Services Task Force". JAMA. 317 (12): 1258–1268. doi:10.1001/jama.2016.10395. PMID 28350935.

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Celiac_disease_screening&oldid=1304022"