Polyarteritis nodosa causes: Difference between revisions

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Revision as of 15:56, 7 April 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Ali Poyan Mehr, M.D. [2] Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3] Cafer Zorkun, M.D., Ph.D. [4]; Haritha Machavarapu, M.B.B.S.

Overview

Causes

The primary cause of PAN is idiopathic, but secondary causes include hepatitis B virus infection ^[1], hepatitis C virus infection, ^[2] and hairy cell leukemia ^[3]. Polyarteritis nodosa is a disease of unknown cause that affects arteries, the blood vessels that carry oxygenated blood to organs and tissues. It occurs when certain immune cells attack the affected arteries. More adults than children get this disease. It damages the tissues supplied by the affected arteries because the tissues are not receiving the oxygen and nourishment they need. People with active Hepatitis B and Hepatitis C may develop this disease.

Drug Side Effect

Sulfasalazine

References

↑ Guillevin L, Mahr A, Callard P, Godmer P, Pagnoux C, Leray E; et al. (2005). "Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients". Medicine (Baltimore). 84 (5): 313–22. PMID 16148731.
↑ Ramos-Casals M, Muñoz S, Medina F, Jara LJ, Rosas J, Calvo-Alen J; et al. (2009). "Systemic autoimmune diseases in patients with hepatitis C virus infection: characterization of 1020 cases (The HISPAMEC Registry)". J Rheumatol. 36 (7): 1442–8. doi:10.3899/jrheum.080874. PMID 19369460.
↑ Hasler P, Kistler H, Gerber H (1995). "Vasculitides in hairy cell leukemia". Semin Arthritis Rheum. 25 (2): 134–42. PMID 8578313.

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[pmid16148731-1] Guillevin L, Mahr A, Callard P, Godmer P, Pagnoux C, Leray E; et al. (2005). "Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients". Medicine (Baltimore). 84 (5): 313–22. PMID 16148731.

[pmid19369460-2] Ramos-Casals M, Muñoz S, Medina F, Jara LJ, Rosas J, Calvo-Alen J; et al. (2009). "Systemic autoimmune diseases in patients with hepatitis C virus infection: characterization of 1020 cases (The HISPAMEC Registry)". J Rheumatol. 36 (7): 1442–8. doi:10.3899/jrheum.080874. PMID 19369460.

[pmid8578313-3] Hasler P, Kistler H, Gerber H (1995). "Vasculitides in hairy cell leukemia". Semin Arthritis Rheum. 25 (2): 134–42. PMID 8578313.

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[2]

[3]

@@ Line 5: / Line 5: @@
 ==Overview==
 ==Causes==
-The primary cause of PAN is idiopathic, but secondary causes include Hepatitis B virus infection <ref name="pmid16148731">{{cite journal| author=Guillevin L, Mahr A, Callard P, Godmer P, Pagnoux C, Leray E et al.| title=Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients. | journal=Medicine (Baltimore) | year= 2005 | volume= 84 | issue= 5 | pages= 313-22 | pmid=16148731 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16148731  }} </ref>, Hepatitis C infection, <ref name="pmid19369460">{{cite journal| author=Ramos-Casals M, Muñoz S, Medina F, Jara LJ, Rosas J, Calvo-Alen J et al.| title=Systemic autoimmune diseases in patients with hepatitis C virus infection: characterization of 1020 cases (The HISPAMEC Registry). | journal=J Rheumatol | year= 2009 | volume= 36 | issue= 7 | pages= 1442-8 | pmid=19369460 | doi=10.3899/jrheum.080874 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19369460  }} </ref>  and Hairy Cell Leukemia <ref name="pmid8578313">{{cite journal| author=Hasler P, Kistler H, Gerber H| title=Vasculitides in hairy cell leukemia. | journal=Semin Arthritis Rheum | year= 1995 | volume= 25 | issue= 2 | pages= 134-42 | pmid=8578313 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8578313  }} </ref>. Polyarteritis nodosa is a disease of unknown cause that affects arteries, the [[blood vessels]] that carry [[oxygenated blood]] to [[organs]] and [[tissues]]. It occurs when certain [[immune cells]] attack the affected arteries.More adults than children get this disease. It damages the tissues supplied by the affected arteries because the tissues are not receiving the oxygen and nourishment they need. People with active [[Hepatitis B]] and [[Hepatitis C]] may develop this disease.
+The primary cause of PAN is idiopathic, but secondary causes include [[hepatitis B virus]] [[infection]] <ref name="pmid16148731">{{cite journal| author=Guillevin L, Mahr A, Callard P, Godmer P, Pagnoux C, Leray E et al.| title=Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients. | journal=Medicine (Baltimore) | year= 2005 | volume= 84 | issue= 5 | pages= 313-22 | pmid=16148731 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16148731  }} </ref>, [[hepatitis C virus]] infection, <ref name="pmid19369460">{{cite journal| author=Ramos-Casals M, Muñoz S, Medina F, Jara LJ, Rosas J, Calvo-Alen J et al.| title=Systemic autoimmune diseases in patients with hepatitis C virus infection: characterization of 1020 cases (The HISPAMEC Registry). | journal=J Rheumatol | year= 2009 | volume= 36 | issue= 7 | pages= 1442-8 | pmid=19369460 | doi=10.3899/jrheum.080874 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19369460  }} </ref> and [[hairy cell leukemia]] <ref name="pmid8578313">{{cite journal| author=Hasler P, Kistler H, Gerber H| title=Vasculitides in hairy cell leukemia. | journal=Semin Arthritis Rheum | year= 1995 | volume= 25 | issue= 2 | pages= 134-42 | pmid=8578313 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8578313  }} </ref>. Polyarteritis nodosa is a disease of unknown cause that affects [[arteries]], the [[blood vessels]] that carry [[oxygenated blood]] to [[organs]] and [[tissues]]. It occurs when certain [[immune cells]] attack the affected arteries. More adults than children get this disease. It damages the [[tissues]] supplied by the affected arteries because the tissues are not receiving the [[oxygen]] and nourishment they need. People with active [[Hepatitis B]] and [[Hepatitis C]] may develop this disease.
 ===Drug Side Effect===