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#[[Weight loss]] ≥4 kg.
#[[Weight loss]] ≥4 kg.
#[[Livedo reticularis]] (a mottled purplish skin discoloration over the extremities or torso).
#[[Livedo reticularis]] (a mottled purplish [[skin]] discoloration over the [[extremities]] or torso).
#[[Testicular pain]] or tenderness. (occasionally, a site biopsied for diagnosis).
#[[Testicular pain]] or [[tenderness]]. (occasionally, a site biopsied for diagnosis).
#[[Muscle pain]], [[weakness]], or [[leg tenderness]].
#[[Muscle pain]], [[weakness]], or [[leg tenderness]].
#Nerve disease (either single or multiple).
#[[Nerve]] [[disease]] (either single or multiple).
#[[Diastolic blood pressure]] greater than 90mmHg (high blood pressure).
#[[Diastolic blood pressure]] greater than 90mmHg (high [[blood pressure]]).
#Elevated kidney blood tests ([[BUN]] greater than 40 mg/dl or [[creatinine]] greater than 1.5 mg/dl).
#Elevated [[kidney]] [[blood]] tests ([[BUN]] greater than 40 mg/dl or [[creatinine]] greater than 1.5 mg/dl).
#[[Hepatitis B]] virus tests positive (for surface antigen or antibody).
#[[Hepatitis B]] virus tests positive (for surface [[antigen]] or [[antibody]]).
#[[Arteriogram]] (angiogram) showing the arteries that are dilated (aneurysms) or constricted by the blood vessel [[inflammation]].
#[[Arteriogram]] (angiogram) showing the arteries that are dilated ([[aneurysms]]) or constricted by the [[blood vessel]] [[inflammation]].
#Biopsy of tissue showing the [[arteritis]] (typically inflamed arteries).
#[[Biopsy]] of [[tissue]] showing the [[arteritis]] (typically inflamed arteries).


==References==
==References==

Latest revision as of 16:03, 7 April 2017

Polyarteritis nodosa Microchapters

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Overview

Historical Perspective

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Differentiating Polyarteritis nodosa from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Haritha Machavarapu, M.B.B.S.

Overview

Diagnostic Criteria

A patient is said to have polyarteritis nodosa if he or she has 3 of the 10 following signs:

  1. Weight loss ≥4 kg.
  2. Livedo reticularis (a mottled purplish skin discoloration over the extremities or torso).
  3. Testicular pain or tenderness. (occasionally, a site biopsied for diagnosis).
  4. Muscle pain, weakness, or leg tenderness.
  5. Nerve disease (either single or multiple).
  6. Diastolic blood pressure greater than 90mmHg (high blood pressure).
  7. Elevated kidney blood tests (BUN greater than 40 mg/dl or creatinine greater than 1.5 mg/dl).
  8. Hepatitis B virus tests positive (for surface antigen or antibody).
  9. Arteriogram (angiogram) showing the arteries that are dilated (aneurysms) or constricted by the blood vessel inflammation.
  10. Biopsy of tissue showing the arteritis (typically inflamed arteries).

References

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