Pleural effusion medical therapy: Difference between revisions

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{{CMG}} {{AE}} {{PTD}}
{{CMG}} {{AE}} {{PTD}}
==Overview==
==Overview==
Treatment aims to remove the fluid(therapeutic [[thoracentesis]]), prevent fluid re-accumulation by way of [[Pleurodesis]]<ref name="pmid26484756">{{cite journal| author=Koegelenberg CF, Vorster MJ| title=Chemical Pleurodesis for Malignant Pleural Effusion: How Far Have We Come in 80 Years? | journal=Respiration | year= 2015 | volume= 90 | issue= 5 | pages= 355-6 | pmid=26484756 | doi=10.1159/000441308 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26484756  }} </ref><ref name="pmid27277376">{{cite journal| author=Hasan R, Khan OS, Aftabuddin M, Razzaque AM, Chowdhury GA| title=A Case of Massive Pleural Effusion: Pleurodesis by Bleomycin. | journal=Mymensingh Med J | year= 2016 | volume= 25 | issue= 2 | pages= 374-8 | pmid=27277376 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27277376  }} </ref>, and treat the underlying cause example antibiotic therapy in infectious causes.<ref name="pmid26449328">{{cite journal| author=Porcel JM, Azzopardi M, Koegelenberg CF, Maldonado F, Rahman NM, Lee YC| title=The diagnosis of pleural effusions. | journal=Expert Rev Respir Med | year= 2015 | volume= 9 | issue= 6 | pages= 801-15 | pmid=26449328 | doi=10.1586/17476348.2015.1098535 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26449328  }} </ref>
Treatment aims to remove the fluid(therapeutic [[thoracentesis]]), prevent fluid re-accumulation by way of [[pleurodesis]]<ref name="pmid26484756">{{cite journal| author=Koegelenberg CF, Vorster MJ| title=Chemical Pleurodesis for Malignant Pleural Effusion: How Far Have We Come in 80 Years? | journal=Respiration | year= 2015 | volume= 90 | issue= 5 | pages= 355-6 | pmid=26484756 | doi=10.1159/000441308 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26484756  }} </ref><ref name="pmid27277376">{{cite journal| author=Hasan R, Khan OS, Aftabuddin M, Razzaque AM, Chowdhury GA| title=A Case of Massive Pleural Effusion: Pleurodesis by Bleomycin. | journal=Mymensingh Med J | year= 2016 | volume= 25 | issue= 2 | pages= 374-8 | pmid=27277376 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27277376  }} </ref>, and treat the underlying cause (e.g. antibiotic therapy in infectious causes).<ref name="pmid26449328">{{cite journal| author=Porcel JM, Azzopardi M, Koegelenberg CF, Maldonado F, Rahman NM, Lee YC| title=The diagnosis of pleural effusions. | journal=Expert Rev Respir Med | year= 2015 | volume= 9 | issue= 6 | pages= 801-15 | pmid=26449328 | doi=10.1586/17476348.2015.1098535 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26449328  }} </ref> In some malignant causes, [[chemotherapy]] may be needed.
In some malignant causes, [[chemotherapy]] may be needed.


==Medical Therapy==
==Medical Therapy==
Treatment aims to<ref name="pmid26449328">{{cite journal| author=Porcel JM, Azzopardi M, Koegelenberg CF, Maldonado F, Rahman NM, Lee YC| title=The diagnosis of pleural effusions. | journal=Expert Rev Respir Med | year= 2015 | volume= 9 | issue= 6 | pages= 801-15 | pmid=26449328 | doi=10.1586/17476348.2015.1098535 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26449328  }} </ref>:
Treatment aims to:<ref name="pmid26449328">{{cite journal| author=Porcel JM, Azzopardi M, Koegelenberg CF, Maldonado F, Rahman NM, Lee YC| title=The diagnosis of pleural effusions. | journal=Expert Rev Respir Med | year= 2015 | volume= 9 | issue= 6 | pages= 801-15 | pmid=26449328 | doi=10.1586/17476348.2015.1098535 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26449328  }} </ref>
*Remove the fluid.
*Remove the fluid
*Prevent fluid from building up again especially in recurring pleural effusion by way of [[Pleurodesis]]<ref name="pmid26484756">{{cite journal| author=Koegelenberg CF, Vorster MJ| title=Chemical Pleurodesis for Malignant Pleural Effusion: How Far Have We Come in 80 Years? | journal=Respiration | year= 2015 | volume= 90 | issue= 5 | pages= 355-6 | pmid=26484756 | doi=10.1159/000441308 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26484756  }} </ref><ref name="pmid27277376">{{cite journal| author=Hasan R, Khan OS, Aftabuddin M, Razzaque AM, Chowdhury GA| title=A Case of Massive Pleural Effusion: Pleurodesis by Bleomycin. | journal=Mymensingh Med J | year= 2016 | volume= 25 | issue= 2 | pages= 374-8 | pmid=27277376 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27277376  }} </ref>
*Prevent fluid from building up again especially in recurring pleural effusion by way of [[pleurodesis]]<ref name="pmid26484756">{{cite journal| author=Koegelenberg CF, Vorster MJ| title=Chemical Pleurodesis for Malignant Pleural Effusion: How Far Have We Come in 80 Years? | journal=Respiration | year= 2015 | volume= 90 | issue= 5 | pages= 355-6 | pmid=26484756 | doi=10.1159/000441308 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26484756  }} </ref><ref name="pmid27277376">{{cite journal| author=Hasan R, Khan OS, Aftabuddin M, Razzaque AM, Chowdhury GA| title=A Case of Massive Pleural Effusion: Pleurodesis by Bleomycin. | journal=Mymensingh Med J | year= 2016 | volume= 25 | issue= 2 | pages= 374-8 | pmid=27277376 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27277376  }} </ref>
*Treating the underlying cause of the fluid buildup.
*Treat the underlying cause of the fluid buildup
For example, pleural effusions caused by congestive heart failure are treated with diuretics and other medications needed in [[congestive heart failure]] treatment. Pleural effusions caused by infection are treated with appropriate antibiotics. In people with cancer or infections, the effusion is often treated by using a chest tube for several days to drain the fluid.
For example, pleural effusions caused by congestive heart failure are treated with diuretics and other medications needed in [[congestive heart failure]] treatment. Pleural effusions caused by infection are treated with appropriate antibiotics. In people with [[cancer]] or infections, the effusion is often treated by using a chest tube for several days to drain the fluid.
 
*Therapeutic [[thoracentesis]].
In some malignant causes, the following may be done:
*[[Chemotherapy]].


*Therapeutic [[thoracentesis]]
In some malignant causes, [[Chemotherapy]] may be prescribed.
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 18:59, 10 April 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2]

Overview

Treatment aims to remove the fluid(therapeutic thoracentesis), prevent fluid re-accumulation by way of pleurodesis[1][2], and treat the underlying cause (e.g. antibiotic therapy in infectious causes).[3] In some malignant causes, chemotherapy may be needed.

Medical Therapy

Treatment aims to:[3]

  • Remove the fluid
  • Prevent fluid from building up again especially in recurring pleural effusion by way of pleurodesis[1][2]
  • Treat the underlying cause of the fluid buildup

For example, pleural effusions caused by congestive heart failure are treated with diuretics and other medications needed in congestive heart failure treatment. Pleural effusions caused by infection are treated with appropriate antibiotics. In people with cancer or infections, the effusion is often treated by using a chest tube for several days to drain the fluid.

In some malignant causes, Chemotherapy may be prescribed.

References

  1. 1.0 1.1 Koegelenberg CF, Vorster MJ (2015). "Chemical Pleurodesis for Malignant Pleural Effusion: How Far Have We Come in 80 Years?". Respiration. 90 (5): 355–6. doi:10.1159/000441308. PMID 26484756.
  2. 2.0 2.1 Hasan R, Khan OS, Aftabuddin M, Razzaque AM, Chowdhury GA (2016). "A Case of Massive Pleural Effusion: Pleurodesis by Bleomycin". Mymensingh Med J. 25 (2): 374–8. PMID 27277376.
  3. 3.0 3.1 Porcel JM, Azzopardi M, Koegelenberg CF, Maldonado F, Rahman NM, Lee YC (2015). "The diagnosis of pleural effusions". Expert Rev Respir Med. 9 (6): 801–15. doi:10.1586/17476348.2015.1098535. PMID 26449328.

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